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Bidirectional synaptic plasticity can explain bidirectional retrograde effects of emotion on memory

Published online by Cambridge University Press:  05 January 2017

Bryan A. Strange  and
Ana Galarza-Vallejo
Bryan A. Strange
Affiliation:
Laboratory for Clinical Neuroscience, Centro de Tecnología Biomédica, Universidad Politecnica de Madrid, Pozuelo de Alarcón, Madrid 28223, [email protected]@ctb.upm.eswww.thestrangelab.org Department of Neuroimaging, Reina Sofia Centre for Alzheimer's Research, Madrid 28031, Spain
Ana Galarza-Vallejo
Affiliation:
Laboratory for Clinical Neuroscience, Centro de Tecnología Biomédica, Universidad Politecnica de Madrid, Pozuelo de Alarcón, Madrid 28223, [email protected]@ctb.upm.eswww.thestrangelab.org
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Abstract

Emotional events can either impair or enhance memory for immediately preceding items. The GANE model explains this bidirectional effect as a glutamate “priority” signal that modulates noradrenaline release depending on arousal state. We argue for an alternative explanation: that priority itself evokes phasic noradrenaline release. Thus, contrasting E-1 memory effects are explained by a mechanism based on the Bienenstock–Cooper–Munro theory.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 39 , 2016 , e224
Copyright
Copyright © Cambridge University Press 2016 

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References

Abraham, W. C. & Tate, W. P. (1997) Metaplasticity: A new vista across the field of synaptic plasticity. Progress in Neurobiology 52(4):303–23.Google Scholar
Anderson, A. K., Wais, P. E. & Gabrieli, J. D. E. (2006) Emotion enhances remembrance of neutral events past. Proceedings of the National Academy of Sciences of the United States of America 103(5):1599–604. doi: 10.1073/pnas.0506308103.Google Scholar
Aston-Jones, G., Rajkowski, J., Kubiak, P. & Alexinsky, T. (1994) Locus coeruleus neurons in monkey are selectively activated by attended cues in a vigilance task. The Journal of Neuroscience 14(7):4467–80.Google Scholar
Bienenstock, E. L., Cooper, L. N. & Munro, P. W. (1982) Theory for the development of neuron selectivity: Orientation specificity and binocular interaction in visual cortex. The Journal of Neuroscience 2(1):32–48.Google Scholar
Diamond, D. M., Park, C. R. & Woodson, J. C. (2004) Stress generates emotional memories and retrograde amnesia by inducing an endogenous form of hippocampal LTP. Hippocampus 14(3):281–91.Google Scholar
Dudek, S. M. & Bear, M. F. (1992) Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade. Proceedings of the National Academy of Sciences of the United States of America 89(10):4363–67.Google Scholar
Hu, H., Real, E., Takamiya, K., Kang, M.-G., Ledoux, J., Huganir, R. L. & Malinow, R. (2007) Emotion enhances learning via norepinephrine regulation of AMPA-receptor trafficking. Cell 131(1):160–73.CrossRefGoogle ScholarPubMed
Kemp, A. & Manahan-Vaughan, D. (2008) β-adrenoreceptors comprise a critical element in learning-facilitated long-term plasticity. Cerebral Cortex 18(6):1326–34.Google Scholar
Kim, J. J. & Yoon, K. S. (1998) Stress: Metaplastic effects in the hippocampus. Trends in Neurosciences 21(12):505–509.Google Scholar
Knight, M. & Mather, M. (2009) Reconciling findings of emotion-induced memory enhancement and impairment of preceding items. Emotion 9(6):763–81. doi: 10.1037/a0017281.Google Scholar
Strange, B. A. & Dolan, R. J. (2004) Beta-adrenergic modulation of emotional memory-evoked human amygdala and hippocampal responses. Proceedings of the National Academy of Sciences of the United States of America 101(31):11454–58.Google Scholar
Strange, B. A., Hurlemann, R. & Dolan, R. J. (2003) An emotion-induced retrograde amnesia in humans is amygdala- and beta-adrenergic-dependent. Proceedings of the National Academy of Sciences of the United States of America 100(23):13626–31. Available at: http://www.ncbi.nlm.nih.gov/pubmed/14595032.Google Scholar