Head-on collisions of spiral galaxies can bring large quantities of gas out of spiral disks and into the intergalactic medium. Only two clear cases (UGC 12914/5 and UGC 813/6) of such collisions are known (Condon et al. 1993, 2002) and in both cases several 109 M⊙ of neutral gas is found in the bridge between the two galaxies which are now separating. About half of the gas is molecular. The gas, atomic or molecular, is brought out by collisions between clouds, which then acquire an intermediate velocity and end up between the galaxies. The bridges contain no old stars and in each case only one HII region despite the large masses of molecular gas, such that the star formation efficiency is very low in the bridges. The collisions occurred 20 – 50 million years ago, much greater than the collapse time for dense cores. We (Braine et al. 2003, 2004) show that collisions between molecular clouds, and not only between atomic gas clouds, bring gas into the bridges. It is not currently known whether the galaxies and bridges are bound or whether they will continue to separate, releasing several 109 M⊙ of neutral gas into the intergalactic medium.