The present study investigated whether dietary n-3 very-long-chain PUFAs (n-3 VLC-PUFAs) could increase skin and bone mineralization in Atlantic salmon (Salmo salar) in vivo and examined their potential effects on human osteoblast proliferation and differentiation in vitro. Atlantic salmon were fed different dietary levels of n-3 VLC-PUFA, and changes in tissue n-3 VLC-PUFA composition, skeletal morphology, skin and bone mineral content, bone mineral density (BMD), and gene expression patterns were examined. Additionally, in vitro experiments using human foetal osteoblast cells were conducted to investigate the potential influence of n-3 VLC-PUFA supplementation on cell proliferation, osteogenic differentiation, and cytokine expression. The results demonstrated that increasing the dietary levels of n-3 VLC-PUFAs increased the mineral content of vertebrae and BMD in salmon, with subtle yet significant impacts on the expression of genes involved in bone-related processes. Furthermore, in vitro experiments showed a potential contextual influence of n-3 VLC-PUFA supplementation on gene expression of osteogenic markers and cytokine expression. Our findings indicate for the first time that n-3 VLC-PUFAs may influence processes related to bone mineralization.

The current scholarship on Ku Hung-Ming (1857–1928) as a translator and a historical figure has been constrained by identity politics and has viewed his translations and writings as a passive response to the challenge of the Western powers from a Chinese nationalist, or as a process of Ku's identity-building. This article goes beyond these constraints and recognises Ku as an active critic of Western modernity. By drawing on narrative theory, it investigates Ku's three broad choices regarding his translated Confucian classics—translation directionality, the invocation of Goethe, and the use of language mixing on the title pages and/or in the front matter—to demonstrate that Ku's translation agenda was to critique Western modernity. This article constitutes a paradigm shift in the research on Ku's translation of Confucian classics, and challenges what I call the ‘eccentricity thesis’ in Ku Hung-Ming studies to raise awareness of Ku as a critic of modernity.

Following the work of Mazzeo–Swoboda–Weiß–Witt [Duke Math. J. 165 (2016), 2227–2271] and Mochizuki [J. Topol. 9 (2016), 1021–1073], there is a map $\overline{\Xi }$ between the algebraic compactification of the Dolbeault moduli space of ${\rm SL}(2,\mathbb{C})$ Higgs bundles on a smooth projective curve coming from the $\mathbb{C}^\ast$ action and the analytic compactification of Hitchin’s moduli space of solutions to the $\mathsf{SU}(2)$ self-duality equations on a Riemann surface obtained by adding solutions to the decoupled equations, known as ‘limiting configurations’. This map extends the classical Kobayashi–Hitchin correspondence. The main result that this article will show is that $\overline{\Xi }$ fails to be continuous at the boundary over a certain subset of the discriminant locus of the Hitchin fibration.

We use a combination of primary and secondary data to investigate and quantify the impacts of the COVID-19 pandemic on the California specialty crop sector. We demonstrate that the specialty crop sector was highly resilient during the pandemic and aftermath in terms of output. For many crops, production fell somewhat between 2019 and 2021, but not to an extent that is outside of normal annual variation for fruits and vegetables. However, prices increased dramatically for many commodities. Contrary to conventional wisdom, most input costs did not surge during the pandemic, and some fell. But both the primary and secondary data identify labor and truck transportation as the major issues facing producers and driving up prices. Trade associations played a vital role in disseminating solutions to growers throughout the pandemic.

Data irregularities, namely small disjuncts, class skew, imbalance, and outliers significantly affect the performance of classifiers. Another challenge posed to classifiers is when new unlabelled data have different characteristics than the training data; this change is termed as a data shift. In this paper, we focus on identifying small disjuncts and dataset shift using the supervised classifier, sequential ellipsoidal partitioning classifier (SEP-C). This method iteratively partitions the dataset into minimum-volume ellipsoids that contain points of the same label, based on the idea of Reduced Convex Hulls. By allowing an ellipsoid that contains points of one label to contain a few points of the other, such small disjuncts may be identified. Similarly, if new points are accommodated only by expanding one or more of the ellipsoids, then shifts in data can be identified. Small disjuncts are distribution-based irregularities that may be considered as being rare but more error-prone than large disjuncts. Eliminating small disjuncts by removal or pruning is seen to affect the learning of the classifier adversely. Dataset shifts have been identified using Bayesian methods, use of confidence scores, and thresholds—these require prior knowledge of the distributions or heuristics. SEP-C is agnostic of the underlying data distributions, uses a single hyperparameter, and as ellipsoidal partitions are generated, well-known statistical tests can be performed to detect shifts in data; it is also applicable as a supervised classifier when the datasets are highly skewed and imbalanced. We demonstrate the performance of SEP-C with UCI, MNIST handwritten digit image, and synthetically generated datasets.

We enrich the class of power-constructible functions, introduced in [CCRS23], to a class $\mathcal {C}^{\mathcal {M,F}}$ of algebras of functions which contains all complex powers of subanalytic functions and their parametric Mellin and Fourier transforms, and which is stable under parametric integration. By describing a set of generators of a special prepared form, we deduce information on the asymptotics and on the loci of integrability of the functions of $\mathcal {C}^{\mathcal {M,F}}$. We furthermore identify a subclass $\mathcal {C}^{\mathbb {C},\mathcal {F}}$ of $\mathcal {C}^{\mathcal {M,F}}$, which is the smallest class containing all power-constructible functions and stable under parametric Fourier transforms and right-composition with subanalytic maps. This class is also stable under parametric integration, under taking pointwise and $\text {L}^p$-limits and under parametric Fourier-Plancherel transforms. Finally, we give a full asymptotic expansion in the power-logarithmic scale, uniformly in the parameters, for functions in $\mathcal {C}^{\mathbb {C},\mathcal {F}}$.

We provide an explicit formula for all primary genus-zero $r$-spin invariants. Our formula is piecewise polynomial in the monodromies at each marked point and in $r$. To deduce the structure of these invariants, we use a tropical realisation of the corresponding cohomological field theories. We observe that the collection of all Witten–Dijkgraaf–Verlinde–Verlinde (WDVV) relations is equivalent to the relations deduced from the fact that genus-zero tropical CohFT cycles are balanced.

A growing number of analysts use the term “judicial populism” to refer to judicial behavior that they find problematic, but they apply it to divergent phenomena and find it objectionable for different reasons. What, then, is judicial populism, and when and why should it be of concern? Taking a deductive approach, I argue that judicial populism is best understood as a performance/discursive style, analytically distinct from judicial activism. Like judicial activism, it is a gradational concept, and both populism and activism may present in judicial behavior to different degrees and in different combinations. To illustrate, I develop a grid matrix with an X-axis that runs from maximal restraint/deference to maximal creativity/dominance in the content of judicial rulings (the “what”) and a Y-axis that runs from maximally removed and technocratic to maximally proximate and publicly oriented in the performance or communication of the judicial role (the “how”). This two-dimensional framework enables nuanced comparison of judicial behavior in disparate times, places, and issue areas, illuminating relative variations and trends therein. It also helps to illustrate that, from a pluralist and deliberative democratic perspective, it is not judicial populism per se that should trouble democrats but, rather, populist behavior taken to extremes.

Broad cultural similarities are apparent between Neolithic sites across the Middle Nile Valley, yet local variation may also be witnessed. The dearth of well-preserved skeletal assemblages in this region means that biological connections between populations, and thus potential modes for the transmission of material culture, are not well understood. Here, the authors compare dental morphological traits in five Neolithic cemeteries (c. 5600–3800 BC) and 14 time-successive sites to explore biological relatedness along the Middle Nile Valley. Their findings parallel the artefactual evidence, suggesting that the spread of the Nubian Neolithic may have been as nuanced as the populations who practised it.

What is a populist judge, and when do judges embrace populism? Populist judges bypass legal and procedural constraints, seek an unmediated relationship with the public, and claim to represent the public better than political elites. Judicial populism can emerge in response to institutionalized dissonance in the political system. Dissonant institutionalization facilitates contestation between state institutions and can undermine the legitimacy of political institutions. This legitimacy crisis can imbue judges with a belief in their role as representatives of the public interest. In Pakistan, the dissonance caused by unresolved differences between the civil-military bureaucracy and the elected political leadership—differences that were embedded into the constitutional framework, facilitated the rise of judicial populism. I outline the key features of judicial populism and study the dynamics surrounding the rapid expansion of populist jurisprudence between 2005 and 2019 in Pakistan, with a focus on public interest litigation that became the cornerstone of the judiciary’s populist turn. Through case analysis, archival research, and semi-structured interviews, I discuss features of the populist approach to jurisprudence and trace how dissonance within Pakistan’s political system created new opportunities for the judiciary and changed judicial role conceptions within the legal and judicial community.

KSB stability holds at codimension $1$ points trivially, and it is quite well understood at codimension $2$ points because we have a complete classification of $2$-dimensional slc singularities. We show that it is automatic in codimension $3$.

In the Triassic Mercia Mudstone Group of the Bristol Channel area, SW Britain, yellow micritic-oolitic dolomites deposited in a near-shore location of an extensive shallow saline alkaline lake, pass landwards into conglomerates and sandstones of colluvial-fluvial origin (Dolomitic Conglomerate). Offshore facies are red marl (Branscombe Fm.) and grey-green marl (Blue Anchor Fm.) of shallow lake-playa origin. Conspicuous red silicified bands and nodules (cherts) occur within the shoreline dolomites cropping out at Clevedon, 30 km SW of Bristol. The originally aragonitic ooids and lime mud were dolomitized very early on the lake floor and just below, and the presence of pyrite indicates anoxic conditions therein. The silicification is attributed to the influx of meteoric water with near-neutral pH, provided by flash floods and rainstorms as hyperpycnal and hypopycnal flows, interacting with the silica-rich, saline, alkaline lake water and porewater within the lake sediment. Aragonitic ooids picked up in the flows underwent dissolution, then slight compaction of outer dolomitic lamellae, before silica precipitation. The red colour of the chert from detrital finely disseminated hematite also indicates very early precipitation, before suboxic-anoxic conditions developed in the enclosing lake carbonates. These Triassic sediments show features of soft-sediment deformation, attributed to the formation of chert via a silica gel and/or density contrasts of rapid deposition-dewatering, plus possible seismic activity connected to a nearby basin-margin fault.

This article analyses the (post)colonial politics of UK bordering through the lens of monstrosity. Historicising contemporary bordering within colonial-era monsterisations of racialised people and their mobility, we identify four mechanisms through which migrants are constructed and policed as monsters today: animalisation, zombification, criminalisation, and barbarisation. We then examine how the state embodies monstrosity itself through border policies of deterrence and creating ‘hostile environments’. In addition to the instrumentalisation of horror, this entails extending the border’s reach domestically throughout everyday life and internationally through deportation and externalisation measures. We argue these developments embody a new form of state power, depicted as a headless, tentacled Leviathan. Doing so provides insights into monstrosity as a form of liberal statecraft, the local/global diffusion of bordering, the transnationalisation of sovereign power, and the racialisation of citizenship. It also raises important questions about the construction of border violence as a necessary and legitimate monstrosity in (post)colonial liberal societies, the everyday complicity of citizens, and the limits of efforts to humanise monsterised migrants or reform monstrous state institutions. Revealing how within liberal regimes of citizenship and humanitarianism values ‘there be monsters’, we argue, opens space for thinking about abolitionist alternatives in international politics.