Research on the timing of herbicide application on no-till sorghum [Sorghum bicolor (L.) Moench.] planted into undisturbed winter wheat (Triticum aestivum L.) stubble was conducted at North Platte, NE, during 1980–1982. Applying some herbicides 41 and 25 days prior to planting sorghum maintained weed control, reduced sorghum injury, and increased sorghum yields when compared to application at planting. It was necessary to apply cyanazine {2-[[4-chloro-6-(ethylamino)-1,3,5-triazin-2-yl]amino]-2-methylpropanenitrile} at 2.7 kg ai/ha 41 days prior to planting to avoid sorghum injury. Metolachlor [2-chloro-N-(2-ethyl-6-methylphenyl)-N-(2-methoxy-1-methylethyl)acetamide] + 2,4-D [(2,4-dichlorophenoxy)acetic acid] at 2.2 + 0.3 kg/ha reduced grass yields 97, 98, and 99%, while reduction with alachlor [2-chloro-N-(2,6-diethylphenyl)-N-(methoxymethyl)acetamide] + 2,4-D at 2.8 + 0.3 kg/ha was 93, 41, and 63%, respectively, when herbicides were applied 0, 25, and 41 days prior to planting.