Based on considerable archival research in Switzerland and France, this article considers the creation of specialised institutions and centres for scientific research, discussion and information on international questions after the First World War. It analyses the origins and development of the International Studies Conference from 1928 until 1946, and it pays particular attention to the institutional setting provided by the ISC. With the help of an international questionnaire of the League of Nations from the early 1930s the article also discusses the university teaching of IR in the US, Great Britain and on the European continent in the interwar period, and it looks at some of the institutional settings, especially academic institutions (departments, chairs, schools and so on), that were available at the time.