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Patterns of practice in palliative radiotherapy for bone metastases in UK centres

Published online by Cambridge University Press:  08 November 2018

Nida Khan Open the ORCID record for Nida Khan [Opens in a new window]  and
David Green
Nida Khan*
Affiliation:
Sheffield Hallam University, Collegiate Crescent, Sheffield S10 2BP, UK
David Green
Affiliation:
Sheffield Hallam University, Collegiate Crescent, Sheffield S10 2BP, UK
*
Author for correspondence: Nida Khan, E-mail: [email protected]
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Abstract

Background

There is abundant evidence of the comparative efficacy of single-fraction (SF) radiotherapy and multi-fraction (MF) radiotherapy when treating patients with bone metastases. Despite this, previous surveys have shown SF schedules to be underutilised.

Aim

To determine current patterns of practice in patients with bone metastasis and to investigate the factors that influence practice.

Method

An electronic audit was performed amongst 46 physicians, within 7 hospital trusts in the UK. The audit comprised of four hypothetical cases in which consultants and registrars chose which dose and fractionation they would recommend and their reasons for this recommendation.

Results

SF radiotherapy was the most common radiotherapy schedule in hypothetical cases 1, 3 and 4. SF radiotherapy was recommended by 65% of respondents in case 1, 47% in case 2, 89% in case 3 and 46% in case 4. For case 2, 50% proposed MF radiotherapy. For case 4, 22% of respondents recommended Stereotactic Body Radiotherapy (SABR). The following deciding factors were cited as influencing choice of an SF schedule: prognosis, published evidence, performance status and spinal cord compression.

Conclusion

The most common radiotherapy schedule selected was SF. However, there were inter-institution differences regarding the use of SF radiotherapy. Furthermore, the survey had shown that a third of respondents recommended an MF regime, despite evidence supporting the efficacy of an SF schedule.

Keywords

bone metastasesdose fractionationpalliative radiotherapypatterns of practice
Type
Original Article
Information
Journal of Radiotherapy in Practice , Volume 18 , Issue 2 , June 2019 , pp. 116 - 122
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Copyright
© Cambridge University Press 2018 

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Footnotes

Cite this article: Khan N, Green D. (2019) Patterns of practice in palliative radiotherapy for bone metastases in UK centres. Journal of Radiotherapy in Practice18: 116–122. doi: 10.1017/S1460396918000584

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