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The menopausal transition: endocrinological and epidemiological considerations

Published online by Cambridge University Press:  27 September 2011

Barry M. Sherman
Affiliation:
Departments of Internal Medicine and Preventive Medicine, University of Iowa College of Medicine, Iowa City, Iowa
Robert B. Wallace
Affiliation:
Departments of Internal Medicine and Preventive Medicine, University of Iowa College of Medicine, Iowa City, Iowa
Alan E. Treloar
Affiliation:
Departments of Internal Medicine and Preventive Medicine, University of North Carolina, Chapel Hill, North Carolina, USA

Extract

The human menstrual cycle is characterized by a series of dynamic hormonal relationships that result in the regular maturation of ovarian follicles, ovulation and corpus luteum formation. As methodology has changed and improved, it has become possible to examine these events in greater detail. The simple analysis of menstrual cycle length, when done with care in a large number of women over long time spans, has revealed much about the fundamental biological rhythm of the menstrual cycle. Of particular interest are the predictable changes in cycle length and variability that occur at different stages of reproductive life (Treloar et al., 1967; Vollman, 1977). Basal body temperature records add another dimension to the analyses of menstrual cycle length because they permit estimation of the length of the pre- and post-ovulatory phases of the menstrual cycle and provide some index of the integrity of corpus luteum function.

Type
I. Biomedical background
Copyright
Copyright © Cambridge University Press 1979

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References

Bean, J.A., Leeper, J.D., Wallace, R.B., Sherman, B.M. & Treloar, A.E. (1979) Accuracy of recalled menstrual and reproductive history. Am. J. Epidemiol. (in press).Google Scholar
Cargille, C.M. & Rayford, P.L. (1970) Characterization of antisera for human folliclestimulating hormone radioimmunoassay. J. lab. din. Med. 75, 1030.Google ScholarPubMed
Chiazze, L. Jr, Brayer, F.T., Macisco, J. Jr, Parker, M.P. & Duffy, B.J. (1968) The length and variability of the human menstrual cycle. J. Am. med. Ass. 203, 377.CrossRefGoogle ScholarPubMed
Collett, M.E., Wertenberger, G.E. & Fiske, V.M. (1954) The effect of age upon the pattern of the menstrual cycle. Fert. Steril. 5, 437.CrossRefGoogle ScholarPubMed
Costoff, A. & Mahesh, V. (1975) Primordial follicles with normal oocytes in the ovaries of postmenopausal women. J. Am. geriat. Soc. 23(5), 93.CrossRefGoogle ScholarPubMed
Daniell, H.W. (1976) Osteoporosis of the slender smoker. Arch, intern. Med. 136, 298.CrossRefGoogle ScholarPubMed
De Jong, F.H. & Sharpe, R.M. (1976) Evidence of inhibin-like activity in bovine follicular fluid. Nature, Lond. 263, 71.CrossRefGoogle ScholarPubMed
Franchimont, P., Chari, S., Hagelstein, M.T. & Duraiswami, S. (1975) Existence of a folliclestimulating hormone inhibiting factor ‘inhibin’ in bull seminal plasma. Nature, Lond. 257, 402.CrossRefGoogle Scholar
Goldenberg, R.L., Grodin, J.M., Rodbard, D. & Ross, G.T. (1973) Gonadotropins in women with amenorrhea: use of plasma follicle-stimulating hormone to differentiate women with and without ovarian follicles. Am. J. Obstet. Gynec. 116, 1003.CrossRefGoogle ScholarPubMed
Hemsell, D.L., Grodin, J.M., Brenner, P.F., Siiteri, P.K. & MacDonald, P.C. (1974) Plasma precursors of estrogen. II. Correlation of the extent of conversion of plasma androstenedione to estrone with age. J. din. endocr. Metab. 38, 476.CrossRefGoogle ScholarPubMed
Hodgen, G.D., Goodman, A.L., O'Connor, A. & Johnson, D.K. (1977) Menopause in rhesus monkeys: model for study of disorders in the human climacteric. Am. J. Obstet. Gynec. 129, 557.Google Scholar
Korenman, S.G., Stevens, R.H., Carpenter, L.A., Robb, M., Niswender, G.D. & Sherman, B.M. (1974) Estradiol radioimmunoassay without chromatography: procedure, validation and normal values. J. clin. endocr. Metab. 38, 718.CrossRefGoogle ScholarPubMed
Macdonald, P.C., Edman, C.D., Hemsell, D.L., Porter, J.C. & Siiteri, P.K. (1978) Effect of obesity on conversion of plasma androstenedione to estrone in postmenopausal women with and without endometrial cancer. Am. J. Obstet. Gynec. 130, 448.CrossRefGoogle ScholarPubMed
Matsumoto, S., Nogami, Y. & Ohkuri, S. (1962) Statistical studies on menstruation: a criticism on the definition of normal menstruation. Gunma J. med. Sci. 11, 294.Google Scholar
Odell, W.D., Ross, G. & Rayford, P.L. (1967) Radioimmunoassay for luteinizing hormone in human plasma or serum: physiological studies. J. clin. Invest. 46, 248.CrossRefGoogle ScholarPubMed
Reyes, F.I., Winter, J.S.D. & Faiman, C. (1977) Pituitary-ovarian relationships preceding the menopause. Am. J. Obstet. Gynec. 129, 557.CrossRefGoogle ScholarPubMed
Ross, G.T., Cargille, C.M., Lipsett, M.B., Rayford, P.L., Marshall, J.R., Strott, C.A. & Rodbard, D. (1970) Pituitary and gonadal hormones in women throughout reproductive life. J. din. Invest. 55, 699.Google Scholar
Sherman, B.M. & Korenman, S.G. (1974a) Measurement of plasma LH, FSH, estradiol and progesterone in disorders of the human menstrual cycle: the short luteal phase. J. din. endocr. Metab. 38, 89.CrossRefGoogle ScholarPubMed
Sherman, B.M. & Korenman, S.G. (1974b) Measurement of serum LH, FSH, estradiol and progesterone in disorders of the human menstrual cycle: the inadequate luteal phase. J. din. endocr. Metab. 39, 145.CrossRefGoogle ScholarPubMed
Sherman, B.M. & Korenman, S.G. (1975) Hormonal characteristics of the human menstrual cycle throughout reproductive life. J. din. Invest. 55, 699.Google ScholarPubMed
Treloar, A.E., Boynton, R.E., Benn, B.G. & Brown, B.W. (1967) Variation of the human menstrual cycle through reproductive life. Int. J. Fert. 12, 77.Google ScholarPubMed
Van de Wiele, R.L., Bogumil, J., Dyrenfurth, I., Ferin, M., Jewelewicz, R., Warren, M., Rizkallah, T. & Mikhail, G. (1970) Mechanisms regulating the menstrual cycle in women. Recent Prog. Horm. Res. 26, 63.Google Scholar
Van Look, P.F.A., Hunter, W.M., Corker, C.S. & Baird, D.T. (1977a) Failure of positive feedback in normal men and subjects with testicular feminization. Clin. Endocr. 7, 353.CrossRefGoogle ScholarPubMed
Van Look, P.F.A., Lothian, H., Hunter, W.M., Michie, E.A. & Baird, D. (1977b) Hypothalamic-pituitary-ovarian function in perimenopausal women. J. clin. Endocr. 7, 13.CrossRefGoogle ScholarPubMed
Vollman, R.F. (1977) The Menstrual Cycle. Saunders, Philadelphia.Google ScholarPubMed
Wallace, R.B., Sherman, B.M., Bean, J., Leeper, J. & Treloar, A.E. (1978) Breast cancer risk factors: correlation with menstrual cycle patterns. Cancer Res. 38, 4021.Google Scholar