Hostname: page-component-cd9895bd7-jkksz Total loading time: 0 Render date: 2024-12-23T16:22:44.297Z Has data issue: false hasContentIssue false

Prospects of fortification of salt with iron and iodine

Published online by Cambridge University Press:  09 March 2007

Bhattiprolu Sivakumar*
Affiliation:
National Institute of Nutrition, Jamai Osmania Post, Hyderabad – 500 007, India
G. N. V. Brahmam
Affiliation:
National Institute of Nutrition, Jamai Osmania Post, Hyderabad – 500 007, India
K. Madhavan Nair
Affiliation:
National Institute of Nutrition, Jamai Osmania Post, Hyderabad – 500 007, India
S. Ranganathan
Affiliation:
National Institute of Nutrition, Jamai Osmania Post, Hyderabad – 500 007, India
M. Vishnuvardhan Rao
Affiliation:
National Institute of Nutrition, Jamai Osmania Post, Hyderabad – 500 007, India
K. Vijayaraghavan
Affiliation:
National Institute of Nutrition, Jamai Osmania Post, Hyderabad – 500 007, India
Kamala Krishnaswamy
Affiliation:
National Institute of Nutrition, Jamai Osmania Post, Hyderabad – 500 007, India
*
*Corresponding author: Dr B. Sivakumar, fax +91 40 7019074, email [email protected]
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Fortification of salt with iron has been developed by the National Institute of Nutrition (NIN) as a strategy for the control of iron deficiency anaemia (IDA) in India, similar to iodization of salt for control of iodine deficiency disorders (IDD). Stability of the iron fortified salt (IFS), its bioavailability and organoleptic evaluation of food items containing the IFS have been demonstrated. Acceptability and effectiveness of the IFS in school children and in multicentric community trials have been demonstrated. With the introduction of universal iodization of salt as a national policy in 1988, NIN has developed a formulation for double fortification (DFS) of salt with iodine and iron. The stability of the nutrients under laboratory conditions along with their bioavailability were found to be good but varying with the quality of salt used. The DFS has been evaluated in controlled trials in tribal communities and in residential school children. The findings of these studies are discussed. Overall, in these trials, DFS effectively controlled iodine deficiency but a clear impact on reducing anaemia was not demonstrated. In residential schoolchildren, increased urinary excretion of iodine as well as reduced anaemia were observed. The quality of salt has been found to be an important determinant of the stability of iodine in DFS. Further evaluation of this potentially important intervention is in progress.

Type
Research Article
Copyright
Copyright © The Nutrition Society 2001

References

Brahmam, GNV, Madhavan Nair, K, Ranganathan, S, Gal Reddy, Ch, Vishnuvardhan Rao, M, Nadamuni Naidu, A, Pralhad, Rao & Vinodini, Reddy (1994) Use of common salt fortified with iron and iodine (double fortified salt) — a community study in Andhra Pradesh National Institute of Nutrition, ICMR, Hyderabad.Google Scholar
Brahmam, GNV, Nair, , MK, , Laxmaiah, A, Gal Reddy, Ch, Ranganathan, S, Vishnuvardhana Rao, M, Nadamuni Naidu, A, Vijayaraghavan, K, Sivakumar, B, Krishnaswamy, K, Gowrinath Sastry, J, Mohanram, M, Pralhad Rao, N & Reddy, V (2000) Community trials with iron and iodine fortified salt (double fortified salt). Proceedings of the 8th World Salt Symposium6–8 May 2000The Hague, The Netherlands, pp. 955960.Google Scholar
Central Bureau of Health Intelligence (1993) Directorate-General of Health Services, Ministry of Health and Family Welfare, Government of India, Nirman Bhavan, New Delhi. Health Information in India.Google Scholar
Department of Women & Child Welfare (1993) Ministry of Human Resource Development, Government of India, New Delhi. A National Nutrition Policy.Google Scholar
ICMR Task Force study (1989) Epidemiological survey of endemic goitre and endemic cretinism 1039 ICMR,New Delhi.Google Scholar
ICMR (1994) Annual Report of Director-General 19939426,pp. 26. Indian Council of Medical Research, New Delhi.Google Scholar
INACG Consensus Statement (1999) Safety of iron supplementation programs in malaria — endemic regions.Washington, DC:INACG Secretariat, ILSI.Google Scholar
Lotfi, M, Venkatesh Mannar, MG, Merx, RJHM & den, Hauvel (1996 b) Review of research and current practices in micronutrient fortification. In Micronutrient Fortification of Foods — Current Practices, Research and Opportunities 3979. Ottawa, Canada: Micronutrient Initiative (IDRC).Google Scholar
Lotfi, M, Venkatesh, Mannar MG, Merx, RJHM and den, Hauvel PN (1996) Food vehicles and fortificants Micronutrient Fortification of Foods — Current Practices, Research and Opportunities 1124.Google Scholar
Nadiger, HA, Krishnamachari, KAVR, Nadamuni Naidu, A, Narasinga Rao, BS & Srikantia, SG (1980) The use of common salt (sodium chloride) fortified with iron to control anaemia — results of a preliminary study. British Journal of Nutrition 43, 4551.Google Scholar
Nair, KM, Brahmam, GNV, Ranganathan, S, Vijayaraghavan, K, Sivakumar, B & Kamala, Krishnaswamy (1998) Impact evaluation of iron and iodine fortified salt. Indian Journal of Medical Research 108, 203211.Google Scholar
Nair, KM, Sesikaran, B, Ranganathan, S & Sivakumar, B (1998) Bioeffect and safety of long term feeding of common salt fortified with iron and iodine (double fortified salt) in rat. Nutrition Research 18, 121129.CrossRefGoogle Scholar
Nair, KM, Brahmam, GNV, Lakshmaiah, A, Gal Reddy, Ch, Vishnuvardhan Rao, M, Ranganathan, S, Vijayaraghavan, K, Sivakumar, B, Kamala, Krishnaswamy (2000) Sodium hexametaphosphate (SHMP) as a stabilizer of double fortified (iron and iodine) salt does not alter the calcium and phosphorus homeostasis. Proceedings of the 8th World Salt Symposium. 6–11 May 2000, pp. 12531254. The Hague, The Netherlands.Google Scholar
Narasinga Rao, BS (1994) Fortification of salt with iron and iodine to control anaemia and goitre. Development of a new formula with good stability and bioavailability of iron and iodine. Food and Nutrition Bulletin 15, 3239.Google Scholar
Narasinga Rao, BS & Prabhavathi, T (1982) Tannin content of foods commonly consumed in India and its influence on ionisable iron. Journal of Science Food and Agriculture 33, 8996.Google ScholarPubMed
Narasinga Rao, BS & Vijayasarathy, C (1975) Fortification of common salt with iron: effect of chemical additives on stability and bioavailability. American Journal of Clinical Nutrition 28, 13951401.Google Scholar
Narasinga Rao, BS & Vijayasarathy, C (1978) An alternate formula for the fortification of common salt with iron. American Journal of Clinical Nutrition 31, 11121114.Google Scholar
Pandav, C (1997) Sustaining elimination of iodine deficiency disorders in South Asia. In Malnutrition in South Asia — A Regional Profile [Gillespie, S, editor]. Khatmandu, Nepal: UNICEF Regional Office for South Asia, Rosa Publication No. 5.Google Scholar
Ranganathan, S, Reddy, V & Ramamoorthy, P (1996) Large scale production of salt fortified with iodine and iron. Food and Nutrition Bulletin 17, 7378.Google Scholar
Report of the Working Group on Fortification of Salt with Iron(1982) Use of common salt fortified with iron in the control and prevention of anaemia — a collaborative study. American Journal of Clinical Nutrition 35, 14421451.CrossRefGoogle Scholar
Sattarzadeh, M & Zlotkin, SH (1999) Iron is well absorbed by healthy adults after ingestion of double fortified (iron and dextran-coated iodine) table salt and urinary iodine excretion is unaffected. Journal of Nutrition 129, 117121.Google Scholar
Seshadri, S (1997) Nutritional anaemia in South Asia. In Malnutrition in South Asia. A Regional Profile, pp. 145159 [Gillespie, S, editor]. Khatmandu, Nepal: UNICEF Regional Office for South Asia, Rosa Publication No. 5.Google Scholar
Sooch, SS, Deo, MG, Karmarkar, MG, Kochupillai, N, Ramachandran, K & Ramalingaswamy, V (1973) Prevention of endemic goitre with iodised salt. Bulletin of World Health Organization 49, 307312.Google Scholar
Suwanik, R and the Study Group; Bangkok (1978) Iron and iodine fortification in Thailand. Bangkok: Faculty of Medicine, Siriraj Hospital, Mahidol University.Google Scholar
VenkateshMannar, MG & Dunn, JT (1995) In Salt Iodization for the Elimination of Iodine Deficiency. The Netherlands: ICCIDD.Google Scholar
World Health Organization (1997) Elimination of iodine deficiency disorders in South-East Asia. A report of the Regional Consultation, SEA/NUT/ 138. New Delhi.Google Scholar
World Health Organization (1998) Nutritional status of adolescent girls and women of reproductive age. A report of the Regional conference. New Delhi: WHO, SEARO.Google Scholar