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Chapter 16 - Autism and autism spectrum disorders

Published online by Cambridge University Press:  05 October 2012

By
Daniel H. Geschwind  and
Maricela Alarcón
Edited by
John I. Nurnberger, Jr  and
Wade Berrettini
John I. Nurnberger, Jr
Affiliation:
Indiana University School of Medicine
Wade Berrettini
Affiliation:
University of Pennsylvania School of Medicine
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Summary

Abstract

Autism is a heterogeneous and broadly defined neurodevelopmental disorder. After a decade or so of intense genetic investigations, diverse approaches, from genetic linkage and whole genome association, to comparative genomic hybridization have begun to yield significant dividends. These genetic findings demonstrate more heterogeneity than initially anticipated, but have also begun to shed light on potential neurobiological mechanisms of this vexing spectrum of conditions.

Keywords

phobic disordersgeneticsgenome searchesgenetic variancegeneralized anxiety disordergenetic epidemiologyagoraphobia
Type
Chapter
Information
Principles of Psychiatric Genetics , pp. 183 - 195
Publisher: Cambridge University Press
Print publication year: 2012

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