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Chapter 19 - The epidemiology of preeclampsia with focus on family data

from Section 7: - Risk factors, predictors, and future management

Published online by Cambridge University Press:  06 July 2010

By
Rolv Skjaerven ,
Kari K. Melve  and
Lars J. Vatten
Edited by
Robert Pijnenborg ,
Ivo Brosens  and
Roberto Romero
Robert Pijnenborg
Affiliation:
University Hospital Gasthuisberg, Leuven
Ivo Brosens
Affiliation:
Leuven Institute for Fertility and Embryology
Roberto Romero
Affiliation:
National Institute of Child Health and Human Development, Detroit
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Summary

This review of epidemiological aspects of preeclampsia focuses on family data, with particular emphasis on the recurrence of preeclampsia within sibships and between generations. Preeclampsia has been a major cause of stillbirth and infant mortality. The great improvement related to stillbirth is clearly the result of induced early delivery of the most severe cases of preeclampsia. Usually, recurrence of preeclampsia is studied using data from two successive pregnancies, preferably the first and second pregnancy. Preeclampsia is related to increased risk of a perinatal death, and it is well documented that fertility subsequent to a perinatal death is increased. First birth and high maternal age are well known risk factors for preeclampsia. The relation between preeclampsia and fetal growth restriction is well established. In recent years the proportion of preeclampsia with preterm delivery has increased due to early induction of pregnancy.

Keywords

assisted conception cyclesdeeper zonal anatomyIVF cyclesuterusultrasoundjunctional zone myometriumjunctional zone contractions
Type
Chapter
Information
Placental Bed Disorders
Basic Science and its Translation to Obstetrics
 , pp. 195 - 206
Publisher: Cambridge University Press
Print publication year: 2010

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