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Section 4 - Fetal Stromal-Vascular Pathology

Published online by Cambridge University Press:  03 September 2018

Raymond W. Redline
Affiliation:
Case Western Reserve University, Ohio
Theonia K. Boyd
Affiliation:
Harvard Medical School, Boston
Drucilla J. Roberts
Affiliation:
Harvard Medical School, Boston
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Publisher: Cambridge University Press
Print publication year: 2017

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References

References

Altshuler, G. Chorangiosis: An important placental sign of neonatal morbidity and mortality. Arch Pathol Lab Med. 1984;108.Google Scholar
Huynh, J, Yamada, J, Beauharnais, C, et al. Type 1, type 2 and gestational diabetes mellitus differentially impact placental pathologic characteristics of uteroplacental malperfusion. Placenta. 2015;36:1161–6.Google Scholar
Akbulut, M, Sorkun, HC, Bir, F, et al. Chorangiosis: the potential role of smoking and air pollution. Pathol Res Pract. 2009;205:7581.CrossRefGoogle ScholarPubMed
Mutema, G, Stanek, J. Increased prevalence of chorangiosis in placentas from multiple gestation. Am J Clin Pathol. 1997;108:341.Google Scholar
Soma, H, Watanabe, Y, Hata, T. Chorangiosis and chorangioma in three cohorts of placentas from Nepal, Tibet and Japan. Reprod Fertil Devel. 1996;7:1533–8.Google Scholar
van Oppenraaij, RH, Koning, AH, van den Hoff, MJ, et al. The effect of smoking on early chorionic villous vascularisation. Placenta. 2012;33:645–51.Google Scholar
Kadyrov, M, Kosanke, G, Kingdom, J, et al. Increased fetoplacental angiogenesis during first trimester in anaemic women. Lancet. 1998;352:1747–9.Google Scholar
Ogino, S, Redline, RW. Villous capillary lesions of the placenta: Distinctions between chorangioma, chorangiomatosis, and chorangiosis. Hum Pathol. 2000;31:945–54.Google Scholar
Jirkovska, M, Kucera, T, Kalab, J, et al. The branching pattern of villous capillaries and structural changes of placental terminal villi in type 1 diabetes mellitus. Placenta. 2012;33:343–51.Google Scholar
Jirkovska, M, Kucera, T, Dvorakova, V, et al. Impact of maternal diabetes type 1 on proliferative potential, differentiation and apoptotic activity in villous capillaries of term placenta. Placenta. 2016;40:17.Google Scholar
Pfarrer, C, Macara, L, Leiser, R, et al. Adaptive angiogenesis in placentas of heavy smokers. Lancet. 1999;354:303.CrossRefGoogle ScholarPubMed
Tissot van Patot, MC, Bendrick-Peart, J, Beckey, VE, et al. Greater vascularity, lowered HIF-1/DNA binding, and elevated GSH as markers of adaptation to in vivo chronic hypoxia. Am J Physiol Lung Cell Mol Physiol. 2004;287:L525–32.Google Scholar
Hiden, U, Glitzner, E, Hartmann, M, et al. Insulin and the IGF system in the human placenta of normal and diabetic pregnancies. J Anat. 2009;215:60–8.Google Scholar
McCowan, LM, Becroft, DM. Beckwith-Wiedemann syndrome, placental abnormalities, and gestational proteinuric hypertension. Obstet Gynecol. 1994;83:813–7.Google Scholar
Schwartz, DA. Chorangiosis and its precursors: underdiagnosed placental indicators of chronic fetal hypoxia. Obstet Gynecol Surv. 2001;56:523–5.Google Scholar
Benirschke, K. Recent trends in chorangiomas, especially those of multiple and recurrent chorangiomas. Pediat Devel Pathol. 1999;2:264–9.Google Scholar
Visentin, S, Selmin, A, Grumolato, F, et al. Infantile hemangioma (IH) in newborn from placenta with hemangioma (chorangioma CH): Report of 18 cases of IH in 38 cases of CH. Placenta. 2013;34:A19.Google Scholar
Mulliken, JB, Bischoff, J, Kozakewich, HP. Multifocal rapidly involuting congenital hemangioma: a link to chorangioma. Am J Med Genet A. 2007;143A:3038–46.Google Scholar
Gallot, D, Marceau, G, Laurichesse-Delmas, H, et al. The changes in angiogenic gene expression in recurrent multiple chorioangiomas. Fetal Diagn Ther. 2007;22:161–8.Google Scholar
Chan, KW, Leung, CY. Recurrent multiple chorioangiomas and intrauterine death. Pathology. 1988;20:77–8.Google Scholar
Reshetnikova, OS, Burton, GJ, Milovanoc, AP, et al. Increased incidence of placental chorioangioma in high-altitude pregnancies:hypobaric hypoxia as a possible etiologic factor. Am J Obstet Gynecol. 1996;174:557–61.Google Scholar
North, PE, Waner, M, Mizeracki, A, et al. A unique microvascular phenotype shared by juvenile hemangiomas and human placenta. Arch Dermatol. 2001;137:559–70.Google Scholar
Khong, TY. Chorangioma with trophoblastic proliferation. Virchows Arch. 2000;436:167–71.Google Scholar
Faes, T, Pecceu, A, Van Calenbergh, S, et al. Chorangiocarcinoma of the placenta: a case report and clinical review. Placenta. 2012;33:658–61.Google Scholar
Sirotkina, M, Douroudis, K, Westgren, M, et al. Association of chorangiomas to hypoxia-related placental changes in singleton and multiple pregnancy placentas. Placenta. 2016;39:154–9.Google Scholar
Mucitelli, DR, Charles, EZ, Kraus, FT. Chorioangiomas of intermediate size and intrauterine growth retardation. Pathol Res Pract. 1990;186:455–8.Google Scholar
Burrows, S, Gaines, JL, Hughes, FJ. Giant chorangioma. Am J Obstet Gynecol. 1973;115:579–80.Google Scholar
Jones, EEM, Rivers, RPA, Taghizadeh, A. Disseminated intravascular coagulation and fetal hydrops in a newborn infant in association with a chorangioma of placenta. Pediatrics. 1972;50:901–5.Google Scholar
Takayama, M, Soma, H, Yaguchi, S, et al. Abnormally large placenta associated with Beckwith-Wiedemann syndrome. Gynecol Obstet Invest. 1986;22:165–8.Google Scholar
Bagby, C, Redline, RW. Multifocal chorangiomatosis. Pediatr Dev Pathol. 2010;14:3844.Google Scholar
Tai, M, Piskorski, A, Kao, J, et al. Placental pathology in fetal alcohol spectrum disorders. Alcohol and Alcoholism. 2017;52:138–44.Google Scholar
Momeni Boroujeni, A, Yousefi, E, Vincent, MT, et al. Chorangiomatosis: Evaluation of a placental vascular lesion and related clinical effects. Fetal Pediatr Pathol. 2014;33:331–8.Google Scholar
Redline, R. Distal villous immaturity. Diagn Histopathol. 2012;18 (5):189–94.Google Scholar
Driscoll, SG. The pathology of pregnancy complicated by diabetes mellitus. Med Clin N Amer. 1965;49:1053–67.CrossRefGoogle Scholar
Higgins, M, McAuliffe, FM, Mooney, EE. Clinical associations with a placental diagnosis of delayed villous maturation: a retrospective study. Pediatr Dev Pathol. 2011;14:273–9.Google Scholar
Mando, C, Calabrese, S, Mazzocco, MI, et al. Sex specific adaptations in placental biometry of overweight and obese women. Placenta. 2016;38:17.Google Scholar
de Laat, MW, van der Meij, JJ, Visser, GH, et al. Hypercoiling of the umbilical cord and placental maturation defect: associated pathology? Pediatr Dev Pathol. 2007;10:293–9.CrossRefGoogle ScholarPubMed
Dicke, JM, Huettner, P, Yan, S, et al. Umbilical artery Doppler indices in small for gestational age fetuses: correlation with adverse outcomes and placental abnormalities. J Ultrasound Med. 2009;28:1603–10.Google Scholar
Stallmach, T, Hebisch, G, Meier, K, et al. Rescue by birth: Defective placental maturation and late fetal mortality. Obstet Gynecol. 2001;97:505–9.Google Scholar
Rodriguez-Moran, M, Levario-Carrillo, M, Gonzalez, JL, et al. Placental immaturity and hyperinsulinaemia in full-term newborns. Eur J Clin Invest. 2007;37:529–34.Google Scholar
NMcCarthy, WA, Popek, EJ. Persistence of villous immaturity in term deliveries following intrauterine transfusion for parvovirus B19 infection and RhD-associated hemolytic disease of the fetus and newborn. Pediatr Dev Pathol. 2017;20: 469–74.Google Scholar
Khong, TY, Mooney, EE, Ariel, I, et al. Sampling and Definitions of Placental Lesions: Amsterdam Placental Workshop Group Consensus Statement. Arch Pathol Lab Med. 2016;140:698713.Google Scholar
Al-Adnani, M, Marnerides, A, George, S, et al. “Delayed Villous Maturation” in Placental Reporting: Concordance among Consultant Pediatric Pathologists at a Single Specialist Center. Pediatr Dev Pathol. 2015;18:375–9.Google Scholar
Seidmann, L, Suhan, T, Kamyshanskiy, Y, et al. CD15 – a new marker of pathological villous immaturity of the term placenta. Placenta. 2014;35:925–31.Google Scholar
Treacy, A, Higgins, M, Kearney, JM, et al. Delayed villous maturation of the placenta: quantitative assessment in different cohorts. Pediatr Dev Pathol. 2013;16:63–6.Google Scholar
Harteman, JC, Nikkels, PG, Benders, MJ, et al. Placental pathology in full-term infants with hypoxic-ischemic neonatal encephalopathy and association with magnetic resonance imaging pattern of brain injury. J Pediatr. 2013;163:968.CrossRefGoogle ScholarPubMed
Paciencia, M, Dolley, P, Jeanne-Pasquier, C, et al. [Acute-placental dysfunction by villous-maturation defect and late-fetal mortality]. J Gynecol Obstet Biol Reprod (Paris). 2008;37:602–7.Google Scholar
Redline, RW, Hassold, T, Zaragoza, MV. Prevalence of the partial molar phenotype in triploidy of maternal and paternal origin. Hum Pathol. 1998;28:505–11.Google Scholar
Redline, RW, Hassold, T, Zaragoza, MV. Determinants of trophoblast hyperplasia in spontaneous abortions. Mod Pathol. 1998;11:762–8.Google Scholar
Redline, RW, Zaragoza, MV, Hassold, T. Prevalence of developmental and inflammatory lesions in non-molar first trimester spontaneous abortions. Hum Pathol. 1999;30:93100.Google Scholar
Novak, R, Agamanolis, D, Dasu, S, et al. Histologic analysis of placental tissue in first trimester abortions. Pediatr Pathol. 1988;8:477–82.Google Scholar
Genest, DR, Roberts, D, Boyd, T, et al. Fetoplacental histology as a predictor of karyotype: a controlled study of spontaneous first trimester abortions. Hum Pathol. 1995;26:201–9.CrossRefGoogle ScholarPubMed
Dillon, J, Gonzalez, JL, Parks, WT, et al. Frequent aneuploidy detection in non-molar conceptuses by molecular analysis of products of conception with atypical villus morphology. Mod Pathol. 2017;30 Suppl 2:282A.Google Scholar
Walker, CK, Anderson, KW, Milano, KM, et al. Trophoblast inclusions are significantly increased in the placentas of children in families at risk for autism. Biol Psychiatry. 2013;74:204–11.Google Scholar
Adler, E, Madankumar, R, Rosner, M, et al. Increased placental trophoblast inclusions in placenta accreta. Placenta. 2014;35:1075–8.Google Scholar
Odom, LN, Segars, J. Imprinting disorders and assisted reproductive technology. Curr Opin Endocrinol Diabetes Obes. 2010;17:517–22.CrossRefGoogle ScholarPubMed
Wilkins-Haug, L, Greene, MF, Roberts, DJ, et al. Frequency of confined placental mosaicism in pregnancies with intrauterine growth retardation. 1992;166:350.Google Scholar
Yong, PJ, von Dadelszen, P, McFadden, DE, et al. Placental weight in pregnancies with trisomy confined to the placenta. J Obstet Gynaecol Can. 2009;31:605–10.Google Scholar
Wilkins-Haug, L, Quade, B, Morton, CC. Confined placental mosaicism as a risk factor among newborns with fetal growth restriction. Prenat Diagn. 2006;26:428–32.Google Scholar
Kliman, HJ, Segel, L. The placenta may predict the baby. J Theor Biol. 2003;225:143–5.Google Scholar
van Lijnschoten, G, Arends, JW, De La Fuente, AA, et al. Intra- and inter-observer variation in the interpretation of histological features suggesting chromosomal abnormality in early abortion specimens. Histopathology. 1993;22:25–9.Google Scholar
Faye-Petersen, OM, Kapur, RP. Placental Mesenchymal Dysplasia. Surg Pathol Clin. 2013;6:127–51.Google Scholar
Pham, T, Steele, J, Stayboldt, C, et al. Placental mesenchymal dysplasia is associated with high rates of intrauterine growth restriction and fetal demise: A report of 11 new cases and a review of the literature. Am J Clin Pathol. 2006;126:6778.Google Scholar
Kaiser-Rogers, KA, McFadden, DE, Livasy, CA, et al. Androgenetic/biparental mosaicism causes placental mesenchymal dysplasia. J Med Genet. 2006;43:187–92.Google ScholarPubMed
Armes, JE, McGown, I, Williams, M, et al. The placenta in Beckwith-Wiedemann syndrome: genotype-phenotype associations, excessive extravillous trophoblast and placental mesenchymal dysplasia. Pathology. 2012;44:519–27.CrossRefGoogle ScholarPubMed
Hoffner, L, Dunn, J, Esposito, N, et al. P57KIP2 immunostaining and molecular cytogenetics: combined approach aids in diagnosis of morphologically challenging cases with molar phenotype and in detecting androgenetic cell lines in mosaic/chimeric conceptions. Hum Pathol. 2008;39:6372.Google Scholar
Lewis, GH, DeScipio, C, Murphy, KM, et al. Characterization of androgenetic/biparental mosaic/chimeric conceptions, including those with a molar component: morphology, p57 immnohistochemistry, molecular genotyping, and risk of persistent gestational trophoblastic disease. Int J Gynecol Pathol. 2013;32:199214.Google Scholar
Umazume, T, Kataoka, S, Kamamuta, K, et al. Placental mesenchymal dysplasia, a case of intrauterine sudden death of fetus with rupture of cirsoid periumbilical chorionic vessels. Diagn Pathol. 2011;6:38.Google Scholar
Pawoo, N, Heller, DS. Placental mesenchymal dysplasia. Arch Pathol Lab Med. 2014;138:1247–9.Google Scholar
Jauniaux, E, Nicolaides, KH, Hustin, J. Perinatal features associated with placental mesenchymal dysplasia. Placenta. 1997;18:701–6.Google Scholar
Weksberg, R, Shuman, C, Beckwith, JB. Beckwith-Wiedemann syndrome. Eur J Hum Genet. 2010;18:814.CrossRefGoogle ScholarPubMed
Lin, J, Cole, BL, Qin, X, et al. Occult androgenetic-biparental mosaicism and sporadic hepatic mesenchymal hamartoma. Pediatr Dev Pathol. 2011;14:360–9.Google Scholar

References

Chan, JS, Baergen, RN. Gross umbilical cord complications are associated with placental lesions of circulatory stasis and fetal hypoxia. Pediatr Dev Pathol. 2012;15:487–94.Google Scholar
Ryan, WD, Trivedi, N, Benirschke, K, et al. Placental histologic criteria for diagnosis of cord accident: sensitivity and specificity. Pediatr Dev Pathol. 2012;15:275–80.Google Scholar
Tantbirojn, P, Saleemuddin, A, Sirois, K, et al. Gross abnormalities of the umbilical cord: related placental histology and clinical significance. Placenta. 2009;30:1083–88.Google Scholar
Parast, MM, Crum, CP, Boyd, TK. Placental histologic criteria for umbilical blood flow restriction in unexplained stillbirth. Hum Pathol. 2008;39:948–53.Google Scholar
Chisholm, KM, Heerema-McKenney, A. Fetal Thrombotic Vasculopathy: Significance in liveborn children using proposed Society for Pediatric Pathology diagnostic criteria. Am J Surg Pathol. 2015;39:274–80.Google Scholar
Saleemuddin, A, Tantbirojn, P, Sirois, K, et al. Obstetric and perinatal complications in placentas with fetal thrombotic vasculopathy. Pediatr Dev Pathol. 2010;13:459–64.CrossRefGoogle ScholarPubMed
Ernst, LM, Minturn, L, Huang, MH, et al. Gross patterns of umbilical cord coiling: correlations with placental histology and stillbirth. Placenta. 2013;34:583–8.Google Scholar
Khong, Y, Mooney, EE, Ariel, I, et al. Sampling and Definitions of Placental Lesions: Amsterdam Placental Workshop Group Consensus Statement. Arch Pathol Lab Med. 2016;140:698713.Google Scholar
Chisholm, KM, Heerema-McKenney, A. Fetal thrombotic vasculopathy: significance in live born children using proposed society for pediatric pathology diagnostic criteria. Am J Surg Pathol. 2015;39:274–80.Google Scholar
Redline, RW, Ariel, I, Baergen, RN, et al. Fetal vascular obstructive lesions: nosology and reproducibility of placental reaction patterns. Pediatr Dev Pathol. 2004;7:443–52.Google Scholar
Strong, TH Jr, Jarles, DL, Vega, JS, et al. The umbilical coiling index. Am J Obstet Gynecol. 1994;170:2932.Google Scholar
Mittal, A, Nanda, S, Sen, J. Antenatal umbilical coiling index as a predictor of perinatal outcome. Arch Gynecol Obstet. 2015;291:763–8.Google Scholar
Dutman, AC, Nikkels, PG. Umbilical hypercoiling in 2nd- and 3rd-trimester intrauterine fetal death. Pediatr Dev Pathol. 2015;18:10–6.Google Scholar
Georgiadis, L, Keski-Nisula, L, Harju, M, et al. Umbilical cord length in singleton gestations: a Finnish population-based retrospective register study. Placenta. 2014;35:275–80.Google Scholar
Baergen, RN, Malicki, D, Behling, C. Morbidity, mortality, and placental pathology in excessively long umbilical cords: retrospective study. Pediatr Dev Pathol. 2001;4:144–53.Google Scholar
Proctor, LK, Fitzgerald, B, Whittle, WL, et al. Umbilical cord diameter percentile curves and their correlation to birth weight and placental pathology. Placenta. 2013;34:62–6.CrossRefGoogle ScholarPubMed
Parast, MM, Crum, CP, Boyd, TK. Placental histologic criteria for umbilical blood flow restriction in unexplained stillbirth. Hum Pathol. 2008;39:948–53.Google Scholar
Desa, DJ. Intimal cushions in foetal placental veins. J Pathol. 1973;110:347–52.Google Scholar
Genest, DR. Estimating the time of death in stillborn fetuses: II. Histologic evaluation of the placenta; a study of 71 stillborns. Obstet Gynecol. 1992;80:585–92.Google Scholar
Treacy, A, Higgins, M, Kearney, JM, et al. Delayed villous maturation of the placenta: quantitative assessment in different cohorts. Pediatr Dev Pathol. 2013;16:63–6.Google Scholar
Stallmach, T, Hebisch, G, Meier, K, et al. Rescue by birth: defective placental maturation and late fetal mortality. Obstet Gynecol. 2001;97:505–9.Google ScholarPubMed
Pathak, S, Lees, CC, Hackett, G, et al. Frequency and clinical significance of placental histological lesions in an unselected population at or near term. Virchows Arch. 2011;459:565–72.Google Scholar
Leistra-Leistra, MJ, Timmer, A, van Spronsen, FJ, et al. Fetal thrombotic vasculopathy in the placenta: a thrombophilic connection between pregnancy complications and neonatal thrombosis? Placenta. 2004;25 SupplA:S102–5.Google Scholar
Ernst, LM, Bit-Ivan, EN, Miller, ES, et al. Stillbirth: correlations between brain injury and placental pathology. Pediatr Dev Pathol. 2016;19:237243.Google Scholar
Chang, KT, Keating, S, Costa, S, et al. Third-trimester stillbirths: correlative neuropathology and placental pathology. Pediatr Dev Pathol. 2011;14:345–52.Google Scholar
Redline, RW, Pappin, A. Fetal thrombotic vasculopathy: the clinical significance of extensive avascular villi. Hum Pathol. 1995;26:8085.Google Scholar
Redline, RW. Cerebral palsy in term infants: a clinicopathologic analysis of 158 medicolegal case reviews. Pediatr Dev Pathol. 2008;11:456–64.Google Scholar
Redline, RW. Severe fetal placental vascular lesions in term infants with neurologic impairment. Am J Obstet Gynecol. 2005;192:452–57.Google Scholar
Wintermark, P, Boyd, T, Parast, MM, et al. Fetal placental thrombosis and neonatal implications. Am J Perinatol. 2010;27:251–56.Google Scholar
Bernson-Leung, ME, Boyd, TK, Meserve, EE, et al. Placental pathology in neonatal stroke: A retrospective case-control study. J Pediatr. 2018; 195:39–47.Google Scholar
Dahms, BB, Boyd, T, Redline, RW. Severe perinatal liver disease associated with fetal thrombotic vasculopathy. Pediatr Dev Pathol. 2002;5:80–5.Google Scholar

References

Kaplan, C, Blanc, WA, Elias, J. Identification of erythrocytes in intervillous thrombi: a study using immunoperoxidase identification of hemoglobins. Hum Pathol 1982;13:554–7.Google Scholar
Basnet, K, Bentley-Lewis, R, Wexler, DJ, Kilic, F, Roberts, DJ. The prevalence of intervillous thrombi is increased in placentas from pregnancies complicated by diabetes. Pediatr Dev Pathol. 2015.Google Scholar
He, M, Curran, P, Raker, C, Martin, S, Larson, L, Bourjeily, G. Placental findings associated with maternal obesity at early pregnancy. Pathol Res Pract 2016;212:282–7.Google Scholar
Chen, Y, Huang, L, Zhang, H, Klebanoff, M, Yang, Z, Zhang, J. Racial disparity in placental pathology in the collaborative perinatal project. International journal of clinical and experimental pathology 2015;8:15042–54.Google Scholar
Vedmedovska, N, Rezeberga, D, Teibe, U, Melderis, I, Donders, GG. Placental pathology in fetal growth restriction. Eur J Obstet Gynecol Reprod Biol 2011;155:3640.Google Scholar
Rolschau, J. Infarctions and intervillous thrombosis in placenta, and their association with intrauterine growth retardation. Acta obstetricia et gynecologica Scandinavica Supplement 1978;72:22–7.Google Scholar
Pathak, S, Sebire, NJ, Hook, L, et al. Relationship between placental morphology and histological findings in an unselected population near term. Virchows Arch 2011;459:1120.Google Scholar
Becroft, DM, Thompson, JM, Mitchell, EA. Placental infarcts, intervillous fibrin plaques, and intervillous thrombi: incidences, cooccurrences, and epidemiological associations. Pediatr Dev Pathol 2004;7:2634.Google Scholar
Stolla, M, Refaii, MA, Conley, G, Katzman, PJ. Placental chorionic cysts contain protrombotic fluid that may trigger thrombosis after cyst rupture. Pediatr Dev Pathol. 2016;19(6):502–05.Google Scholar
Devi, B, Jennison, RF, Langley, FA. Significance of placental pathology in transplacental haemorrhage. J Clin Pathol 1968;21:322–31.Google Scholar
Batcup, G, Tovey, LA, Longster, G. Fetomaternal blood group incompatibility studies in placental intervillous thrombosis. Placenta 1983;4 Spec No:449–53.Google Scholar
Altshuler, G, Arizawa, M, Molnar-Nadasdy, G. Meconium-induced umbilical cord vascular necrosis and ulceration: a potential link between the placenta and poor pregnancy outcome. Obstet Gynecol 1992;79:760–6.Google Scholar
Mooney, EE, al Shunnar, A, O’Regan, M, Gillan, JE. Chorionic villous haemorrhage is associated with retroplacental haemorrhage. Br J Obstet Gynaecol 1994;101:965–9.Google Scholar
Aladjem, S, Sander, CH. Intravillous hemorrhage. Arch Pathol Lab Med 1981;105:499500.Google Scholar
Gilman Barber, AR, Rhone, SA, Fluker, MR. Curettage and Asherman’s syndrome-lessons to (re-) learn? J Obstet Gynaecol Can 2014;36:9971001.Google Scholar
Genest, D, Ringer, SA. Placental findings correlate with neonatal death in extremely premature infants. A study of 150 cases. Lab Invest 1993;68:126a.Google Scholar
Kovalovszki, L, Villanyi, E, Benko, G. Placental villous edema: a possible cause of antenatal hypoxia. Acta paediatrica Hungarica 1990;30:209–15.Google Scholar
Redline, RW, Wilson-Costello, D, Borawski, E, Fanaroff, AA, Hack, M. Placental lesions associated with neurologic impairment and cerebral palsy in very low-birth-weight infants. Arch Pathol Lab Med 1998;122:1091–8.Google Scholar
Machin, GA. Hydrops revisited: literature review of 1,414 cases published in the 1980s. Am J Med Genet 1989;34:366–90.Google Scholar
Urbaniak, SJ, Greiss, MA. RhD haemolytic disease of the fetus and the newborn. Blood reviews 2000;14:4461.Google Scholar
Ismail, KM, Martin, WL, Ghosh, S, Whittle, MJ, Kilby, MD. Etiology and outcome of hydrops fetalis. J Matern Fetal Med 2001;10:175–81.Google Scholar
Jackson, GM, Scott, JR. Alloimmune conditions and pregnancy. Bailliere’s clinical obstetrics and gynaecology 1992;6:541–63.Google Scholar
Tiker, F, Gurakan, B, Tarcan, A, Ozbek, N. Fatal course of ABO hemolytic disease associated with hydrops in a twin pregnancy. The Turkish journal of pediatrics 2006;48:73–5.Google Scholar
Ota, S, Sahara, J, Mabuchi, A, Yamamoto, R, Ishii, K, Mitsuda, N. Perinatal and one-year outcomes of non-immune hydrops fetalis by etiology and age at diagnosis. J Obstet Gynaecol Res 2016;42:385–91.Google Scholar
Sohan, K, Carroll, SG, De La Fuente, S, Soothill, P, Kyle, P. Analysis of outcome in hydrops fetalis in relation to gestational age at diagnosis, cause and treatment. Acta Obstet Gynecol Scand 2001;80:726–30.Google Scholar
Society for Maternal-Fetal M, Norton, ME, Chauhan, SP, Dashe, JS. Society for maternal-fetal medicine (SMFM) clinical guideline #7: nonimmune hydrops fetalis. Am J Obstet Gynecol 2015;212:127–39.Google Scholar
Gedikbasi, A, Oztarhan, K, Gunenc, Z, et al. Preeclampsia due to fetal non-immune hydrops: mirror syndrome and review of literature. Hypertens Pregnancy 2011;30:322–30.Google Scholar
Braun, T, Brauer, M, Fuchs, I, et al. Mirror syndrome: a systematic review of fetal associated conditions, maternal presentation and perinatal outcome. Fetal Diagn Ther 2010;27:191203.Google Scholar
McCoy, MC, Katz, VL, Gould, N, Kuller, JA. Non-immune hydrops after 20 weeks’ gestation: review of 10 years’ experience with suggestions for management. Obstet Gynecol 1995;85:578–82.Google Scholar
Redline, R, Minich, N, Taylor, H, Hack, M. Placental lesions as predictors of cerebral palsy and abnormal neurocognitive function at school age in extremely low birth weight infants (< Kg). Pediatr Dev Pathol. 2007;10(4):282–92.Google Scholar
Naeye, RL, Maisels, MJ, Lorenz, RP, Botti, JJ. The clinical significance of placental villous edema. Pediatrics 1983;71:588–94.Google Scholar
Castro, E, Tony Parks, W, Galambos, C. Neither normal nor diseased placentas contain lymphatic vessels. Placenta 2011;32:310–6.Google Scholar
Redline, RW. Cerebral palsy in term infants: a clinicopathologic analysis of 158 medicolegal case reviews. Pediatr Dev Pathol 2008;11:456–64.Google Scholar
Avagliano, L, Locatelli, A, Danti, L, Felis, S, Mecacci, F, Bulfamante, GP. Placental histology in clinically unexpected severe fetal acidemia at term. Early Hum Dev 2015;91:339–43.Google Scholar
Salafia, CM, Minior, VK, Lopez-Zeno, JA, Whittington, SS, Pezzullo, JC, Vintzileos, AM. Relationship between placental histologic features and umbilical cord blood gases in preterm gestations. Am J Obstet Gynecol 1995;173:1058–64.Google Scholar
Malin, GL, Morris, RK, Khan, KS. Strength of association between umbilical cord pH and perinatal and long term outcomes: systematic review and meta-analysis. BMJ 2010;340:c1471.Google Scholar
Creasy, RK, Resnik, R, Iams, JD. Creasy and Resnik’s Maternal-Fetal Medicine Principles and Practice. 7 ed: Elsevier; 2014.Google Scholar
Roberts, DJ, Nadel, A, Lage, J, Rutherford, CJ. An unusual variant of congenital dyserythropoietic anaemia with mild maternal and lethal fetal disease. British journal of haematology 1993;84:549–51.Google Scholar
Sato, Y, Izumi, Y, Minegishi, K, et al. Prenatal findings in congenital leukemia: a case report. Fetal Diagn Ther 2011;29:325–30.Google Scholar
Lentz, SE, Coulson, CC, Gocke, CD, Fantaskey, AP. Placental pathology in maternal and neonatal myeloproliferative disorders. Obstet Gynecol 1998;91:863.Google Scholar
de Tar, MW, Dittman, W, Gilbert, J. Transient myeloproliferative disease of the newborn: case report with placental, cytogenetic, and flow cytometric findings. Hum Pathol 2000;31:396–8.Google Scholar
Ravishankar, S, Hoffman, L, Lertsburapa, T, Welch, J, Treaba, D, De Paepe, ME. Extensive placental choriovascular infiltration by maturing myeloid cells in down syndrome-associated transient abnormal myelopoiesis. Pediatr Dev Pathol 2015;18:231–6.Google Scholar
Al-Buhtori, M, Moore, L, Benbow, EW, Cooper, RJ. Viral detection in hydrops fetalis, spontaneous abortion, and unexplained fetal death in utero. J Med Virol 2011;83:679–84.Google Scholar
Syridou, G, Spanakis, N, Konstantinidou, A, et al. Detection of cytomegalovirus, parvovirus B19 and herpes simplex viruses in cases of intrauterine fetal death: association with pathological findings. J Med Virol 2008;80:1776–82.Google Scholar
Levine, Z, Sherer, DM, Jacobs, A, Rotenberg, O. Nonimmune hydrops fetalis due to congenital syphilis associated with negative intrapartum maternal serology screening. Am J Perinatol 1998;15:233–6.Google Scholar
Young, SA, Crocker, DW. Occult congenital syphilis in macerated stillborn fetuses. Arch Pathol Lab Med 1994;118:44–7.Google Scholar
Bulova, SI, Schwartz, E, Harrer, WV. Hydrops fetalis and congenital syphilis. Pediatrics 1972;49:285–7.Google Scholar
Khodr, G, Matossian, R. Hydrops fetales and congenital toxoplasmosis. Value of direct immunofluorescence test. Obstet Gynecol 1978;51:74s–7s.Google ScholarPubMed
Chen, AL, Goldfarb, IT, Scourtas, AO, Roberts, DJ. The histologic evolution of revealed, acute abruptions. Hum Pathol. 2017;67:187–97.Google Scholar

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