Book contents
- Pediatric Pathology of Hematopoietic and Histiocytic Disorders
- Pediatric Pathology of Hematopoietic and Histiocytic Disorders
- Copyright page
- Epigraph
- Contents
- Contributors
- Section I General Hematology and Hematopathology
- Section II Non-Neoplastic Hematologic Disorders of Blood and Bone Marrow
- Section III Non-Neoplastic Disorders of Extramedullary Lymphoid Tissues
- Chapter 7 Non-Infectious Lymphadenopathy
- Chapter 8 Infectious Lymphadenopathy
- Section IV Neoplastic Disorders of Bone Marrow
- Section V Mature Lymphoid Neoplasms
- Section VI Histiocytic Disorders and Neoplasms
- Index
- References
Chapter 7 - Non-Infectious Lymphadenopathy
from Section III - Non-Neoplastic Disorders of Extramedullary Lymphoid Tissues
Published online by Cambridge University Press: 25 January 2024
Book contents
- Pediatric Pathology of Hematopoietic and Histiocytic Disorders
- Pediatric Pathology of Hematopoietic and Histiocytic Disorders
- Copyright page
- Epigraph
- Contents
- Contributors
- Section I General Hematology and Hematopathology
- Section II Non-Neoplastic Hematologic Disorders of Blood and Bone Marrow
- Section III Non-Neoplastic Disorders of Extramedullary Lymphoid Tissues
- Chapter 7 Non-Infectious Lymphadenopathy
- Chapter 8 Infectious Lymphadenopathy
- Section IV Neoplastic Disorders of Bone Marrow
- Section V Mature Lymphoid Neoplasms
- Section VI Histiocytic Disorders and Neoplasms
- Index
- References
Summary
Benign enlargement of the lymph nodes or other lymphoid organs (e.g., tonsil, spleen, thymus) is a consequence of hyperplasia of some or all of the cellular components, reflecting stimulation of the lymphoid cells or other cells by a variety of pathogens. The common causes include autoimmune disorders, drug or allergen exposures, foreign body reaction, infection with microorganisms, or undetermined etiologies. Its incidence and etiology vary with age. In the majority of children, lymph node enlargement is transient and reversible. When a biopsy is needed for clinical management purposes, the primary goal of histologic evaluation is to determine the nature of the process: whether it is a benign or malignant, hematopoietic or non-hematopoietic cell proliferation.
- Type
- Chapter
- Information
- Publisher: Cambridge University PressPrint publication year: 2024
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