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Case 17 - Multifocal Motor Neuropathy (MMN)

from Peripheral Neuropathies

Published online by Cambridge University Press:  29 November 2024

Jessica E. Hoogendijk
Affiliation:
University Medical Center Utrecht
Marianne de Visser
Affiliation:
Amsterdam University Medical Center
Pieter A. van Doorn
Affiliation:
Erasmus MC, University Medical Center, Rotterdam
Erik H. Niks
Affiliation:
Leiden University Medical Center
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Summary

A 50-year-old man was initially seen by a rheumatologist because he had crooked fingers on the left hand and painful cramps. No rheumatological abnormalities were found. In the next three years, he developed severe atrophy and weakness of the left hand, and could not hold a glass of water. There were no sensory complaints. His GP considered motor neuron disease.

Type
Chapter
Information
Neuromuscular Disease
A Case-Based Approach
, pp. 118 - 121
Publisher: Cambridge University Press
Print publication year: 2024

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References

Suggested Reading

Joint Task Force of the EFNS and the PNS. European Federation of Neurological Societies/Peripheral Nerve Society guideline on management of multifocal motor neuropathy. Report of a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society – first revision. J Peripher Nerv Syst 2010;15(4):295301. doi: 10.1111/j.1529-8027.2010.00290.x. PMID: 21199100.CrossRefGoogle Scholar
Keddie, S, Eftimov, F, van den Berg, LH, et al. Immunoglobulin for multifocal motor neuropathy. Cochrane Database Syst Rev 2022;1(1):CD004429. doi: 10.1002/14651858.CD004429.pub3. PMID: 35015296; PMCID: PMC8751207.Google ScholarPubMed
Oudeman, J, Eftimov, F, Strijkers, GJ, et al. Diagnostic accuracy of MRI and ultrasound in chronic immune-mediated neuropathies. Neurology 2020;94(1):e62e74. doi: 10.1212/WNL.0000000000008697. Epub 2019 Dec 11. PMID: 31827006.CrossRefGoogle ScholarPubMed
Telleman, JA, Herraets, IJ, Goedee, HS, van Asseldonk, JT, Visser, LH. Ultrasound scanning in the diagnosis of peripheral neuropathies. Pract Neurol 2021;21(3):186195. doi: 10.1136/practneurol-2020-002645. Epub 2021 Feb 4. PMID: 33541914.CrossRefGoogle ScholarPubMed
Vlam, L, van der Pol, WL, Cats, EA, et al. Multifocal motor neuropathy: diagnosis, pathogenesis and treatment strategies. Nat Rev Neurol 2011;8(1):4858. doi: 10.1038/nrneurol.2011.175. PMID: 22105211.CrossRefGoogle ScholarPubMed
Yeh, WZ, Dyck, PJ, van den Berg, LH, Kiernan, MC, Taylor, BV. Multifocal motor neuropathy: controversies and priorities. J Neurol Neurosurg Psychiatry 2020;91(2):140148. doi: 10.1136/jnnp-2019-321532. Epub 2019 Sep 11. PMID: 31511307.CrossRefGoogle ScholarPubMed

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