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2 - Renal Handling of Lithium

Proximal and Distal Handling of Lithium; The Staging of Chronic Kidney Disease; Lithium Related Effects on Renal Function

Published online by Cambridge University Press:  09 February 2024

Jonathan M. Meyer  and
Stephen M. Stahl
Jonathan M. Meyer
Affiliation:
University of California, San Diego
Stephen M. Stahl
Affiliation:
University of California, San Diego
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Summary

In a 1989 review entitled “Long-term treatment with lithium and renal function: A review and reappraisal,” the pioneering Danish psychopharmacologist Mogens Schou concluded: “The fear of eventual kidney insufficiency as a result of long-term lithium treatment can be set at rest” [1]. Despite the certainty advanced by the preeminent authority on lithium at that time – the man responsible for all of the early data on lithium’s efficacy and the first double-blind placebo-controlled trials – fear of lithium’s long-term renal adverse effects remains a significant concern to clinicians, a concern that is often disproportionate to the emerging data in this area.

Type
Chapter
Information
The Lithium Handbook
Stahl's Handbooks
 , pp. 95 - 150
Publisher: Cambridge University Press
Print publication year: 2023

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