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3.11.5 - Magnesium

from Section 3.11 - Metabolic Disorders

Published online by Cambridge University Press:  27 July 2023

By
Clare Morkane
Edited by
Ned Gilbert-Kawai ,
Debashish Dutta  and
Carl Waldmann
Ned Gilbert-Kawai
Affiliation:
The Royal Liverpool Hospital
Debashish Dutta
Affiliation:
Princess Alexandra Hospital NHS Trust, Harlow
Carl Waldmann
Affiliation:
Royal Berkshire Hospital, Reading
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Summary

Key Learning Points

  1. 1. Magnesium is the second most important intracellular cation after potassium.

  2. 2. Magnesium antagonises the entry of calcium into cells, preventing excitation.

  3. 3. Treatment of hypomagnesaemia is important in critically ill patients for prevention of cardiac arrhythmias.

  4. 4. When treating hypomagnesaemia, coexisting hypokalaemia should also be corrected.

  5. 5. Magnesium has a role in the treatment of acute severe asthma, pre-eclampsia and eclampsia.

Keywords

magnesiumhypomagnesaemiahypermagnesaemiacationelectrolyte
Type
Chapter
Information
Intensive Care Medicine
The Essential Guide
 , pp. 373 - 374
Publisher: Cambridge University Press
Print publication year: 2021

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References

References and Further Reading

British Thoracic Society. 2021. BTS/SIGN British guideline on the management of asthma. www.brit-thoracic.org.uk/quality-improvement/guidelines/asthma/Google Scholar
Parikh, M, Webb, ST. Cations: potassium, calcium and magnesium. Contin Educ Anaesth Crit Care Pain 2012;12:195–8.CrossRefGoogle Scholar
The Magpie Trial Collaborative Group. Do women with pre-eclampsia, and their babies, benefit from magnesium sulphate? The Magpie Trial: a randomised, placebo-controlled trial. Lancet 2002;359:1877–90.Google Scholar
Weisinger, JR, Bellorín-Font, E. Magnesium and phosphorus. Lancet 1998;352:391–6.CrossRefGoogle ScholarPubMed

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