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Chapter 13 - Sleep

from Section 3 - The Lifestyle Medicine Pillars

Published online by Cambridge University Press:  01 May 2025

Richard Pinder
Affiliation:
Imperial College of Science, Technology and Medicine, London
Christopher-James Harvey
Affiliation:
Imperial College of Science, Technology and Medicine, London
Ellen Fallows
Affiliation:
British Society of Lifestyle Medicine
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Summary

Sleep is a dynamic process that is influenced by our daily behaviours and in turn impacts our waking choices. It’s important to understand that healthy sleep involves not just the duration but also the timing and architecture of sleep, which can affect disease risks and outcomes. The regulation of sleep is driven by the sleep homeostat, also known as Process S, and the circadian system, known as Process C. Sleep itself consists of Non-Rapid Eye Movement (NREM) and Rapid Eye Movement (REM) stages, each with distinct brain wave patterns and physiological functions. The circadian system, which is governed by sunlight and melatonin, synchronises our body’s clocks and regulates physiological rhythms.

There is variability in individual sleep needs, which are influenced by genetics, and these needs change across the lifespan. Poor-quality sleep is linked to mental health issues, cardiovascular disease, diabetes, and other pathologies. Common sleep disorders include insomnia and obstructive sleep apnoea, with lifestyle interventions being key treatments.

Good sleep health can be promoted through regular schedules, optimal bedroom environments, and managing lifestyle factors. Education and policy changes are needed to address sleep issues.

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Publisher: Cambridge University Press
Print publication year: 2025

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References

Keene, A. C. and Duboue, E. R., The origins and evolution of sleep. J Exp Biol. 2018;221(11):jeb159533.CrossRefGoogle ScholarPubMed
Basner, M., Fomberstein, K. M., Razavi, F. M., et al., American time use survey: Sleep time and its relationship to waking activities. Sleep. 2007;30(9):10851095.CrossRefGoogle ScholarPubMed
Borbély, A. A., Daan, S., Wirz‐Justice, A. and Deboer, T., The two‐process model of sleep regulation: A reappraisal. J Sleep Res. 2016;25(2):131143.CrossRefGoogle ScholarPubMed
Landolt, H.-P., Sleep homeostasis: A role for adenosine in humans? Biochem Pharmacol. 2008;75(11):20702079.CrossRefGoogle ScholarPubMed
Van Dongen, H. P., Vitellaro, K. M. and Dinges, D. F., Individual differences in adult human sleep and wakefulness: Leitmotif for a research agenda. Sleep. 2005;28(4):479498.CrossRefGoogle ScholarPubMed
Lane, J. M., Vlasac, I., Anderson, S. G., et al., Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank. Nat Commun. 2016;7(1):10889.CrossRefGoogle ScholarPubMed
Maukonen, M., Havulinna, A. S., Männistö, S., et al., Genetic associations of chronotype in the Finnish general population. J Biol Rhythms. 2020;35(5):501511.CrossRefGoogle ScholarPubMed
Kalmbach, D. A., Schneider, L. D., Cheung, J., et al., Genetic basis of chronotype in humans: Insights from three landmark GWAS. Sleep. 2017;40(2):zsw048.CrossRefGoogle ScholarPubMed
Vink, J. M., Vink, J. M, Groot, A. S., Kerkhof, G. A. and Boomsma, D. I., Genetic analysis of morningness and eveningness. Chronobiol Int. 2001;18(5):809822.CrossRefGoogle ScholarPubMed
Boatswain-Jacques, A.-F., Dusablon, C., Cimon-Paquet, C., et al., From early birds to night owls: A longitudinal study of actigraphy-assessed sleep trajectories during the transition from pre-to early adolescence. Sleep. 2023;46(11):zsad127.CrossRefGoogle ScholarPubMed
Roenneberg, T., Kuehnle, T., Juda, M., et al., Epidemiology of the human circadian clock. Sleep Med Rev. 2007;11(6):429438.Google ScholarPubMed
Baglioni, C., Battagliese, G., Feige, B., et al., Insomnia as a predictor of depression: A meta-analytic evaluation of longitudinal epidemiological studies. J Affect Disord. 2011;135(1–3):1019.CrossRefGoogle ScholarPubMed
Waite, F., Sheaves, B., Isham, L., Reeve, S. and Freeman, D., Sleep and schizophrenia: From epiphenomenon to treatable causal target. Schizophr Res. 2020;221:4456.CrossRefGoogle ScholarPubMed
Purple, R. J., Cosgrave, J., Alexander, I., et al., Phenotypic divergence in sleep and circadian cycles linked by affective state and environmental risk related to psychosis. Sleep. 2023;46(3):zsac311.CrossRefGoogle ScholarPubMed
Alvaro, P. K., Roberts, R. M. and Harris, J. K., A systematic review assessing bidirectionality between sleep disturbances, anxiety, and depression. Sleep. 2013;36(7):10591068.CrossRefGoogle ScholarPubMed
Lee, S., Mu, C. X., Wallace, M. L., et al., Sleep health composites are associated with the risk of heart disease across sex and race. Sci Rep. 2022;12(1):2023.CrossRefGoogle ScholarPubMed
Zuraikat, F. M., Makarem, N., Redline, S., et al., Sleep regularity and cardiometabolic health: Is variability in sleep patterns a risk factor for excess adiposity and glycemic dysregulation? Curr Diab Rep. 2020;20:19.Google Scholar
Zhou, L., Yu, K., Yang, L., et al., Sleep duration, midday napping, and sleep quality and incident stroke: The Dongfeng-Tongji cohort. Neurology. 2020;94(4):e345–e56.CrossRefGoogle ScholarPubMed
Mogavero, M. P., DelRosso, L. M., Fanfulla, F., Bruni, O. and Ferri, R., Sleep disorders and cancer: State of the art and future perspectives. Sleep Med Rev. 2021;56:101409.CrossRefGoogle ScholarPubMed
Zhang, Y. and Papantoniou, K., Night shift work and its carcinogenicity. Lancet Oncol. 2019;20(10):e550.CrossRefGoogle ScholarPubMed
Garbarino, S., Lanteri, P., Bragazzi, N. L., Magnavita, N. and Scoditti, E., Role of sleep deprivation in immune-related disease risk and outcomes. Commun Biol. 2021;4(1):1304.CrossRefGoogle ScholarPubMed
Nedergaard, M. and Goldman, S. A., Glymphatic failure as a final common pathway to dementia. Science. 2020;370(6512):5056.CrossRefGoogle ScholarPubMed
Fadayomi, A. B., Ibala, R., Bilotta, F., Westover, M. B. and Akeju, O., A systematic review and meta-analysis examining the impact of sleep disturbance on post-operative delirium. Crit Care Med. 2018;46(12):e1204.Google Scholar
He, E., Dong, Y., Jia, H. and Yu, L., Relationship of sleep disturbance and postoperative delirium: A systematic review and meta-analysis. Gland Surg. 2022;11(7):1192.CrossRefGoogle ScholarPubMed
Koffel, E., Thuras, P., Chakravorty, S., Germain, A. and Khawaja, I. S., Poor sleep quality at discharge as a predictor of readmission to a psychiatry partial hospitalization program. Prim Care Companion for CNS Disord. 2015;17(6):27109.Google ScholarPubMed
Labrosciano, C., Tavella, R., Reynolds, A., et al., The association between sleep duration and quality with readmissions: An exploratory pilot-study among cardiology inpatients. Clocks & Sleep. 2020;2(2):120142.CrossRefGoogle ScholarPubMed
Romero, E. K., Abdalla, M., Thanataveerat, A., et al., Short sleep duration following hospital evaluation for acute coronary syndrome is associated with increased risk of 6-month readmission. Psychosom Med. 2020;82(1):57.CrossRefGoogle ScholarPubMed
Morin, C. M. and Jarrin, D. C., Epidemiology of insomnia: Prevalence, course, risk factors, and public health burden. Sleep Med Clin. 2022;17(2):173191.CrossRefGoogle ScholarPubMed
Cunningham, J., Hunter, M., Budgeon, C, et al., The prevalence and comorbidities of obstructive sleep apnea in middle-aged men and women: The Busselton Healthy Ageing Study. J Clin Sleep Med. 2021;17(10):20292039.CrossRefGoogle ScholarPubMed
Weaver, T. E., Mancini, C., Maislin, G., et al., Continuous positive airway pressure treatment of sleepy patients with milder obstructive sleep apnea: Results of the CPAP Apnea Trial North American Program (CATNAP) randomized clinical trial. Am J Respir Crit Care Med. 2012;186(7):677683.CrossRefGoogle ScholarPubMed
Olsen, S., Smith, S. S., Oei, T. P. and Douglas, J., Motivational interviewing (MINT) improves continuous positive airway pressure (CPAP) acceptance and adherence: A randomized controlled trial. J Consult Clin Psychol. 2012;80(1):151.CrossRefGoogle ScholarPubMed
Iftikhar, I. H., Kline, C. E. and Youngstedt, S. D., Effects of exercise training on sleep apnea: A meta-analysis. Lung. 2014;192:175184.Google ScholarPubMed
Carneiro‐Barrera, A., Díaz‐Román, A., Guillén‐Riquelme, A. and Buela‐Casal, G., Weight loss and lifestyle interventions for obstructive sleep apnoea in adults: Systematic review and meta‐analysis. Obes Rev. 2019;20(5):750762.CrossRefGoogle ScholarPubMed
Araghi, M. H., Chen, Y.-F., Jagielski, A., et al., Effectiveness of lifestyle interventions on obstructive sleep apnea (OSA): Systematic review and meta-analysis. Sleep. 2013;36(10):15531562.CrossRefGoogle ScholarPubMed
Dauvilliers, Y., Billiard, M. and Montplaisir, J., Clinical aspects and pathophysiology of narcolepsy. Clin Neurophysiol. 2003;114(11):20002017.Google ScholarPubMed
Postuma, R. and Montplaisir, J., Predicting Parkinson’s disease – why, when, and how? Parkinsonism & Relat Disord. 2009;15:S105S109.CrossRefGoogle Scholar
Matricciani, L., Bin, Y. S., Lallukka, T., et al., Past, present, and future: Trends in sleep duration and implications for public health. Sleep Health. 2017;3(5):223228.CrossRefGoogle ScholarPubMed
Fenton, S., Burrows, T., Skinner, J. and Duncan, M., The influence of sleep health on dietary intake: A systematic review and meta‐analysis of intervention studies. J Hum Nutr Diet. 2021;34(2):273285.CrossRefGoogle ScholarPubMed
Lin, J., Jiang, Y., Wang, G., et al., Associations of short sleep duration with appetite-regulating hormones and adipokines: A systematic review and meta-analysis. Obes Rev. 2020;21(11):e13051.CrossRefGoogle ScholarPubMed
Hagger, M. S., Where does sleep fit in models of self-control and health behaviour? Stress and Health. 2014;30(5):425430.CrossRefGoogle Scholar
Axelsson, J., Ingre, M., Kecklund, G., et al., Sleepiness as motivation: A potential mechanism for how sleep deprivation affects behavior. Sleep. 2020;43(6) zsz291.CrossRefGoogle ScholarPubMed
Cullen, T., Thomas, G. and Wadley, A., Sleep deprivation: Cytokine and neuroendocrine effects on perception of effort. Med Sci Sports Exerc. 2020;52(4):909918.CrossRefGoogle ScholarPubMed
Seol, J., Lee, J., Park, I., et al., Bidirectional associations between physical activity and sleep in older adults: A multilevel analysis using polysomnography. Sci Rep. 2022;12(1):15399.Google ScholarPubMed
Driver, H. S. and Taylor, S. R., Exercise and sleep. Sleep Med Rev. 2000;4(4):387402.Google ScholarPubMed
Ebrahim, I. O., Shapiro, C. M., Williams, A. J. and Fenwick, P. B., Alcohol and sleep I: Effects on normal sleep. Alcohol: Clin Exp Res. 2013;37(4):539549.Google ScholarPubMed
Stein, M. D. and Friedmann, P. D., Disturbed sleep and its relationship to alcohol use. Subst Abuse. 2006;26(1):113.Google Scholar
Arnedt, J. T., Conroy, D. A. and Brower, K. J., Treatment options for sleep disturbances during alcohol recovery. J Addict Dis. 2007;26(4):4154.CrossRefGoogle ScholarPubMed
Hertenstein, E., Trinca, E., Wunderlin, M., et al., Cognitive behavioral therapy for insomnia in patients with mental disorders and comorbid insomnia: A systematic review and meta-analysis. Sleep Med Rev. 2022;62:101597.CrossRefGoogle ScholarPubMed
Brower, K. J., Assessment and treatment of insomnia in adult patients with alcohol use disorders. Alcohol. 2015;49(4):417427.CrossRefGoogle ScholarPubMed
Babson, K. A., Sottile, J. and Morabito, D., Cannabis, cannabinoids, and sleep: A review of the literature. Curr Psychiatry Rep. 2017;19:112.CrossRefGoogle ScholarPubMed
Espie, C. A., Kyle, S. D, Hames, P., et al., The sleep condition indicator: A clinical screening tool to evaluate insomnia disorder. BMJ Open. 2014;4(3):e004183.CrossRefGoogle ScholarPubMed
Luik, A. I., Machado, P. F., Siriwardena, N. and Espie, C. A., Screening for insomnia in primary care: Using a two-item version of the sleep condition indicator. Br J Gen Prac. 2019;69(679):7980.CrossRefGoogle ScholarPubMed
De Zambotti, M., Cellini, N., Goldstone, A., Colrain, I. M. and Baker, F. C., Wearable sleep technology in clinical and research settings. Med Sci Sports Exer. 2019;51(7):1538.CrossRefGoogle ScholarPubMed
Evenson, K. R, Goto, M. M and Furberg, R. D, Systematic review of the validity and reliability of consumer-wearable activity trackers. Int J Behav Nutr Phys Act. 2015;12(1):122.CrossRefGoogle ScholarPubMed
Baron, K. G., Abbott, S., Jao, N., Manalo, N. and Mullen, R., Orthosomnia: Are some patients taking the quantified self too far? J Clin Sleep Med. 2017;13(2):351354.CrossRefGoogle ScholarPubMed
Illingworth, G., Sharman, R, Harvey, C.-J., Foster, R. G. and Espie, C. A., The teensleep study: The effectiveness of a school-based sleep education programme at improving early adolescent sleep. Sleep Med: X. 2020;2:100011.Google Scholar
Rigney, G., Watson, A., Gazmararian, J. and Blunden, S., Update on school-based sleep education programs: How far have we come and what has Australia contributed to the field? Sleep Med. 2021;80:134157.CrossRefGoogle ScholarPubMed
Royal Society for Public Health and University of Oxford, Waking up to the Health Benefits of Sleep United Kingdom. London: Royal Society for Public Health, 2016.Google Scholar
Espie, C. A., Emsley, R., Kyle, S. D., et al., Effect of digital cognitive behavioral therapy for insomnia on health, psychological well-being, and sleep-related quality of life: A randomized clinical trial. JAMA Psychiatry. 2019;76(1):2130.CrossRefGoogle ScholarPubMed
Romiszewski, S., May, F. E. K., Homan, E. J., et al., Medical student education in sleep and its disorders is still meagre 20 years on: A cross‐sectional survey of UK undergraduate medical education. J Sleep Res. 2020;29(6):e12980.Google ScholarPubMed
Williamson, A. A., Min, J., Fay, K., et al., A multi-method evaluation of bed provision and sleep education for young children and their families living in poverty. J Clin Sleep Med. 2023;19(9)1583-1594:jcsm.10614.CrossRefGoogle Scholar
Grandner, M. A., Patel, N. P., Gehrman, P. R, et al., Who gets the best sleep? Ethnic and socioeconomic factors related to sleep complaints. Sleep Med. 2010;11(5):470478.CrossRefGoogle ScholarPubMed
Pabayo, R., Patel, P., Liu, S. Y. and Molnar, B. E., Sleepless in inequality: Findings from the 2018 behavioral risk factor surveillance system, a cross-sectional study. BMC Public Health. 2022;22(1):19.CrossRefGoogle ScholarPubMed

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