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Published online by Cambridge University Press: 30 May 2024
The standard two-step scheme for modeling extracellular signals is to first compute the neural membrane currents using multicompartment neuron models (step 1) and next use the volume-conductor theory to compute the extracellular potential resulting from these membrane currents (step 2). We here give a brief introduction to the multicompartment modeling of neurons in step 1. The formalism presented, which has become the gold standard within the field, combines a Hodgkin-Huxley-type description of membrane mechanisms with the cable theory description of the membrane potential in dendrites and axons.
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