Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-cd9895bd7-mkpzs Total loading time: 0 Render date: 2024-12-26T21:43:12.024Z Has data issue: false hasContentIssue false

2.4 - Basic Pharmacology of Specific Neurotransmitter Pathways

from 2 - Neurotransmitters and Receptors

Published online by Cambridge University Press:  08 November 2023

By
Emanuele F. Osimo  and
Stephen M. Stahl
Edited by
Mary-Ellen Lynall ,
Peter B. Jones  and
Stephen M. Stahl
Mary-Ellen Lynall
Affiliation:
University of Cambridge
Peter B. Jones
Affiliation:
University of Cambridge
Stephen M. Stahl
Affiliation:
University of California, San Diego
Get access

Summary

Many substances act as transmitters in the central nervous system. We will focus on those small molecules which have been most implicated in neuropsychiatric conditions, namely serotonin, dopamine, gamma-aminobutyric acid (GABA), noradrenaline, acetylcholine and glutamate; for further reading, see [1] and [2].

Type
Chapter
Information
Cambridge Textbook of Neuroscience for Psychiatrists , pp. 27 - 33
Publisher: Cambridge University Press
Print publication year: 2023

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Kandel, ER, Schwartz, JH, Jessell, TM, Siegelbaum, SA, Hudspeth, AJ. Principles of Neural Science, 5th ed. McGraw-Hill, Health Professions Division, 2013.Google Scholar
Katzung, BG, Masters, SB, Trevor, AJ. Basic and Clinical Pharmacology, 12th ed. McGraw Hill Medical, 2012.Google Scholar
Hariri, AR, Mattay, VS, Tessitore, A et al. Serotonin transporter genetic variation and the response of the human amygdala. Science 2002; 297(5580): 400–403.CrossRefGoogle ScholarPubMed
Lesch, K-P, Bengel, D, Heils, A et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 1996; 274(5292): 1527–1531.CrossRefGoogle ScholarPubMed
Caspi, A, Sugden, K, Moffitt, TE et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 2003; 301(5631): 386–389.CrossRefGoogle ScholarPubMed
Howes, OD, Kapur, S. The dopamine hypothesis of schizophrenia: version III – the final common pathway. Schizophr Bull 2009; 35(3): 549–562.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×