Book contents
- Androgens in Gynecological Practice
- Androgens in Gynecological Practice
- Copyright page
- Contents
- About the editors
- Dedication
- Contributors
- Preface
- Section 1 Managing the basics
- Section 2 The scientific essentials
- Section 3 Learning from the extremes
- 11 Congenital adrenal hyperplasia in females
- 12 Cushing’s syndrome in females
- 13 Androgen-producing ovarian tumors
- 14 Cognitive and behavioral impact of androgen disorders in females: Learning from complete androgen insensitivity syndrome and congenital adrenal hyperplasia
- 15 Testosterone replacement in the aging male: Lessons learned from the Women’s Health Initiative
- Section 4 The tool kit
- Index
- Plate Section
- References
15 - Testosterone replacement in the aging male: Lessons learned from the Women’s Health Initiative
from Section 3 - Learning from the extremes
Published online by Cambridge University Press: 05 July 2015
Book contents
- Androgens in Gynecological Practice
- Androgens in Gynecological Practice
- Copyright page
- Contents
- About the editors
- Dedication
- Contributors
- Preface
- Section 1 Managing the basics
- Section 2 The scientific essentials
- Section 3 Learning from the extremes
- 11 Congenital adrenal hyperplasia in females
- 12 Cushing’s syndrome in females
- 13 Androgen-producing ovarian tumors
- 14 Cognitive and behavioral impact of androgen disorders in females: Learning from complete androgen insensitivity syndrome and congenital adrenal hyperplasia
- 15 Testosterone replacement in the aging male: Lessons learned from the Women’s Health Initiative
- Section 4 The tool kit
- Index
- Plate Section
- References
Summary
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- Information
- Androgens in Gynecological Practice , pp. 151 - 160Publisher: Cambridge University PressPrint publication year: 2015
References
1.Committee on Assessing the Need for Clinical Trials of Testosterone Replacement Therapy. In: Liverman, CT and Blazer, DG (Eds.) Testosterone and Aging: Clinical Research Directions. Washington, DC: National Academy of Sciences,; 2004.Google Scholar
2.Donatucci, CF. The Institute of Medicine white paper on testosterone: current perspective. In: Helstrom, WJG (Ed.) Androgen Deficiency and Testosterone Replacement. New York: Humana Press; 2013: 1–14.Google Scholar
3.Araujo, AB, Esche, GR, Kupelian, V, et al. Prevalence of symptomatic androgen deficiency in men. J Clin Endocrinol Metab 2007; 92:4241–7.Google Scholar
4.Women’s Health Initiative. www.nhlbi.nih.gov/whi/index.html (accessed February 2015).Google Scholar
5.National Institute of Health, Age page. www.nia.nih.gov/health/publication/menopause (accessed October 2012).Google Scholar
6.Grady, D, Rubin, SM, Petitti, DB, et al. Hormone therapy to prevent disease and prolong life in postmenopausal women. Ann Intern Med 1992;117:1016–37.Google Scholar
7.Krieger, N, Löwy, I, Aronowitz, R, et al. Hormone replacement therapy, cancer, controversies, and women’s health: historical, epidemiological, biological, clinical, and advocacy perspectives. J Epidemiol Community Health 2005;59:740–8.CrossRefGoogle ScholarPubMed
8.Million Women Study Collaborators. Patterns of use of hormone replacement therapy in one million women in Britain, 1996–2000. BJOG 2002; 109:1319–30.Google Scholar
9.Million Women Study Collaborators. Breast cancer and hormone replacement therapy in the Million Women Study. Lancet 2003;362:419–27.Google Scholar
10.Faber, A, Bouvy, ML, Loskamp, L, et al. Dramatic change in prescribing of hormone replacement therapy in The Netherlands after publication of the Million Women Study: a follow-up study. Br J Clin Pharmacol 2005;60;641–7.Google Scholar
11.Nelson, HD, Walker, M, Zakher, B, et al. Menopausal hormone therapy for the primary prevention of chronic conditions: a systematic review to update the U.S. Preventive Services Task Force recommendations. Ann Intern Med 2012;157:104–13.Google Scholar
12.Stuenkel, CA, Gass, ML, Manson, JE, et al. A decade after the Women’s Health Initiative–the experts do agree. Menopause 2012;19:846–7.Google Scholar
13.Harman, SM, Metter, EJ, Tobin, JD, et al. Baltimore Longitudinal Study of Aging. Longitudinal effects of aging on serum total and free testosterone levels in healthy men. J Clin Endocrinol Metab 2001;86:724–31.CrossRefGoogle ScholarPubMed
14.Feldman, HA, Longcope, C, Derby, CA, et al. Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts Male Aging Study. J Clin Endocrinol Metab 2002;87:589–98.Google Scholar
15.Liu, PY, Beilin, J, Meier, C, et al. Age-related changes in serum testosterone and sex hormone binding globulin in Australian men: longitudinal analyses of two geographically separate regional cohorts. J Clin Endocrinol Metab 2007;92:3599–603.Google Scholar
16.Wu, FCW, Tajar, A, Pye, SR, et al. Hypothalamic–pituitary–testicular axis disruptions in older men are differentially linked to age and modifiable risk factors: the European Male Aging Study. J Clin Endocrinol Metab 2008;93:2737–45.Google Scholar
17.Veldhuis, JD. Aging and hormones of the hypothalamo–pituitary axis: gonadotropic axis in men and somatotropic axes in men and women. Aging Res Rev 2008;7:189–208.CrossRefGoogle ScholarPubMed
18.Kaufman, JM, Vermeulen, A. The decline of androgen levels in elderly men and its clinical and therapeutic implications. Endocr Rev 2005;26:833–76.CrossRefGoogle ScholarPubMed
19.Morales, A, Spevack, M, Emerson, L, et al. Adding to the controversy: pitfalls in the diagnosis of testosterone deficiency syndromes with questionnaires and biochemistry. Aging Male 2007;10:57–65.Google Scholar
20.Mulligan, T, Frick, MF, Zuraw, QC, et al. Prevalence of hypogonadism in males aged at least 45 years: the HIM study. Int J Clin Pract 2006;60:762–9.Google ScholarPubMed
21.Tajar, A, Forti, G, O’Neill, TW, et al. Characteristics of secondary, primary, and compensated hypogonadism in aging men: evidence from the European Male Ageing Study. J Clin Endocrinol Metab 2010;95:1810–18.Google Scholar
22.Huggins, C, Hodges, CV. Studies on prostate cancer. I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. Cancer Res 1941;1:293–7.Google Scholar
23.Bhasin, S, Cunningham, GR, Hayes, FJ, et al. Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2010: 95: 2536–59.Google Scholar
24.Zitzmann, M, Faber, S, Nieschlag, E. Association of specific symptoms and metabolic risks with serum testosterone in older men. J Clin Endocrinol Metab 2006;91:4335–43.Google Scholar
25.Hall, SA, Esche, GR, Araujo, AB, at al. Correlates of low testosterone and symptomatic androgen deficiency in a population-based sample. J Clin Endocrinol Metab 2008;93:3870–7.Google Scholar
26.Shahidi, NT. A review of the chemistry, biological action, and clinical applications of anabolic-androgenic steroids. Clin Ther 2001;23(9):1355–90.CrossRefGoogle ScholarPubMed
27.Buvat, J, Maggi, M, Guay, A, et al. Testosterone deficiency in men: systematic review and standard operating procedures for diagnosis and treatment. J Sex Med 2013;10:245–84.Google Scholar
28.Svartberg, J, Agledahl, I, Figenschau, Y, et al. Testosterone treatment in elderly men with subnormal testosterone levels improves body composition and BMD in the hip. Int J Impot Res 2008;20:378–87.CrossRefGoogle ScholarPubMed
29.Kwan, M, Greenleaf, WJ, Mann, J, et al. The nature of androgen action on male sexuality: a combined laboratory-self-report study on hypogonadal men. J Clin Endocrinol Metab 1983;57:557–62.Google Scholar
30.Bagatell, CJ, Heiman, JR, Rivier, JE, et al. Effects of endogenous testosterone and estradiol on sexual behavior in normal young men. J Clin Endocrinol Metab 1994; 78:711–16.Google Scholar
31.Kelleher, S, Conway, AJ, Handelsman, DJ. Blood testosterone threshold for androgen deficiency symptoms. J Clin Endocrinol Metab 2004;89:3813–17.Google Scholar
32.Ni, X, Muram, D. Symptomatic improvement in hypogonadal men receiving testosterone replacement therapy as a function of testosterone level: an open-label subgroup analysis. Endocr Rev 33, SUN -75, 2012. Manuscript submitted for publication.Google Scholar
33.Lee, KK, Berman, N, Alexander, GM, et al. A simple self-report diary for assessing psychosexual function in hypogonadal men. J Androl 2003;24:688–98.Google Scholar
34.Wang, C, Cunningham, G, Dobs, A, et al. Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone mineral density in hypogonadal men. J Clin Endocrinol Metab 2004;89:2085–98.Google Scholar
35.Hubert, W. Psychotropic effects of testosterone. In: Nieschlag, EB, Behre, HM (Eds.) Testosterone: Action, Deficiency, Substitution. Berlin, Germany: Springer-Verlag; 1990: 51–71.Google Scholar
36.Saad, F, Aversa, A, Isidori, AM, et al. Onset of effects of testosterone treatment and time span until maximum effects are achieved. Eur J Endocrinol 2011;165:675–85.Google Scholar
37.Zitzmann, M, Mattern, A, Hanisch, J, et al. IPASS: a study on the tolerability and effectiveness of injectable testosterone undecanoate for the treatment of male hypogonadism in a worldwide sample of 1,438 men. J Sex Med. 2013; 10:579–88.Google Scholar
38.Buvat, J, Maggi, M, Gooren, L, et al. Endocrine aspects of male sexual dysfunctions. J Sex Med 2010;7:1627–56.Google Scholar
39.Snyder, PJ, Peachey, H, Hannoush, P, et al. Effect of testosterone treatment on body composition and muscle strength in men over 65 years of age. J Clin Endocrinol Metab 1999;84:2647–53.Google Scholar
40.Isidori, AM, Giannetta, E, Greco, EA, et al. Effects of testosterone on body composition, bone metabolism and serum lipid profile in middle-aged men: a meta-analysis. Clin Endocrinol (Oxf) 2005;63:280–93.Google Scholar
41.Isidori, AM, Giannetta, E, Gianfrilli, D, et al. Effects of testosterone on sexual function in men: results of a meta-analysis. Clin Endocrinol 2005;63:381–94.Google Scholar
42.Fernández-Balsells, MM, Murad, MH, Lane, M, et al. Clinical review 1: adverse effects of testosterone therapy in adult men: a systematic review and meta-analysis. J Clin Endocrinol Metab 2010;95:2560–75.CrossRefGoogle Scholar
43.Randomized, Placebo-controlled, Double-blind Study of Five Coordinated Testosterone Treatment Trials in Older Men (ClinicalTrials.gov Identifier: NCT00799617).Google Scholar