The purpose of this study was to validate the Vocational Rehabilitation-Service-Related Stress Scale (VRSS) with a sample of 429 vocational rehabilitation (VR) service personnel in Japan. Exploratory factor analysis was employed to determine the structure of the VRSS, and confirmatory factor analysis showed that the four-factor model had a good model fit. The internal consistency reliability of the VRSS, as measured by Cronbach's alpha, was .90. Results indicated that the VRSS is a valid and reliable measure that can be used to examine occupational stress in VR personnel. Work-related stress and quality assurance issues that pertain to the delivery of VR services are discussed.