This chapter describes a motivational enhancement therapy (MET) intervention tailored to reach young people who use cannabis. MET intervention also motivates young people to voluntarily participate in a confidential assessment and evaluation of the impact of cannabis on their lives, and offer support to those who wish to quit or reduce use. A general trend toward increased cannabis use for much of the 1990s was particularly marked among teenagers, possibly due to its ready availability and declining perceptions of risk. Developmental tasks of adolescence include increasing psychological autonomy, expanding social roles, development of the capacity for intimacy, and the formation of value systems and life goals. The Teen Cannabis Check-Up is a two-session assessment and feedback intervention developed to reach cannabis users who are neither self-initiating change nor seeking treatment. The chapter describes the variations of cannabis check-up interventions tailored for adolescents and common issues in implementing the check-up approach.