Let $\{b_n\}_{n=1}^{\infty }$ be a sequence of integers larger than 1. We will study the harmonic analysis of the equal-weighted Moran measures $\mu _{\{b_n\},\{{\mathcal D}_n\}}$ with ${\mathcal D}_n=\{0,1,2,\ldots ,q_n-1\}$, where $q_n$ divides $b_n$ for all $n\geq 1.$ In this paper, we first characterize all the maximal orthogonal sets of $L^2(\mu _{\{b_n\},\{{\mathcal D}_n\}})$ via a tree mapping. By this characterization, we give some sufficient conditions for the maximal orthogonal set to be an orthonormal basis.

Let $\{R_{k}\}_{k=1}^{\infty }$ be a sequence of expanding integer matrices in $M_{n}(\mathbb {Z})$ , and let $\{D_{k}\}_{k=1}^{\infty }$ be a sequence of finite digit sets with integer vectors in ${\mathbb Z}^{n}$ . In this paper, we prove that under certain conditions in terms of $(R_{k},D_{k})$ for $k\ge 1$ , the Moran measure

$$ \begin{align*} \mu_{\{R_{k}\},\{D_{k}\}}:=\delta_{R_{1}^{-1}D_{1}}\ast\delta_{R_{1}^{-1}R_{2}^{-1}D_{2}}\ast\cdots \end{align*} $$

$(R,D)$