Control of southern pine species that easily establish from seed, such as loblolly pine and slash pine (wilding pines), has historically been achieved economically through the use of prescribed fire or application of glyphosate or glyphosate and saflufenacil during site preparation. Currently, alternatives to glyphosate are being investigated for wilding pine control because of health and safety concerns over glyphosate reported by some organizations. Two exploratory studies in the Coastal Plain Region of Georgia investigated the potential of several herbicides for wilding pine control with 0.56 to 0.70 kg ha−1 of 0.9-kg ae imazapyr included in all herbicide treatments. Application timings for Study 1 were July and September (n = 8 treatments per timing), whereas Study 2 took place in July and early November (n = 4 treatments per timing). In Study 1, various rates of choline triclopyr, ester triclopyr, fluroxypyr, aminopyralid + florpyrauxifen-benzyl, and aminopyralid + triclopyr were tested, while two treatments contained glyphosate. Study 2 investigated mixtures containing flumioxazin, glufosinate, and triclopyr. Results for Study 1 revealed that the two treatments containing glyphosate had the greatest percent loblolly pine control after 120 d (87.5% and 88.6% control, respectively), while the next best control was offered by a treatment containing imazapyr plus 3.36 kg ha−1 choline triclopyr (52.6% control). July treatments offered better control than September treatments, but the efficacy of September treatments may have been impacted by a severe drought. In Study 2, treatments applied during early November that contained imazapyr and glufosinate or imazapyr, glufosinate, and flumioxazin resulted in 100% control of mixed loblolly and slash pine seedlings and saplings. All November treatments offered better control than July treatments in Study 2. Promising results from Study 2 suggest that glufosinate may warrant additional study for use in forestry site preparation as an alternative to glyphosate to control wilding pines.