This chapter explores the beginning of the end of the emotional regime of Romantic sensibility and the origins of surgical scientific modernity. It illuminates this crucial period of transition through the juxtaposition of two distinct but conceptually and ideologically intertwined moments in surgical history. These are, firstly, the debates surrounding the practice of anatomical dissection that came to the fore in the 1820s and culminated in the passage of the Anatomy Act in 1832, and, secondly, the introduction and early use of inhalation anaesthesia in the later 1840s. In both instances it highlights the powerful influence of utilitarian thought in divesting the body, both as object and subject, of emotional meaning and agency. In the former instance it demonstrates how an ultra-rationalist understanding of sentiment was set in opposition to popular ‘sentimentalism’ in order to divest the dead bodies of the poor of emotional value. Meanwhile, in the latter, it considers how the emotional subjectivity of the newly anaesthetised patient was swiftly tamed by the operations of a techno-scientific rationale.