The Lomas Entierros archaeological site provides a case study of domestic activities in two socioeconomic sectors. Located in Central Pacific Costa Rica, it was a primary center and important node for the exchange of goods throughout the region. In this article, we characterize and compare the domestic and socioeconomic activities at two structures from different sectors of the site through the analysis of micro-remains, chemical residues (phosphates, carbonates, pH, carbohydrates, protein residues, and fatty acids), and starch grains. Our findings show that differences between the two structures were determined both by their function and the socioeconomic status of their occupants. Structure 13, in the elite sector, presents a richer dataset that suggests the cooking of plants and mollusks in the interior of the dwelling. Structure 44, in the intermediate-status sector, has a lower diversity and density of remains, suggesting very low use that may result from its role as a storage space. This article provides a nuanced methodology for the study of domestic spaces in tropical areas.