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2 results

  • Chapter 11 - Bioinformatics

  • from Part 3 - The Methodology of Gene Manipulation
  • Desmond S. T. Nicholl
  • Book:
    An Introduction to Genetic Engineering
    Published online:
    10 February 2023
    Print publication:
    02 March 2023, pp 230-247

  • Summary

    Bioinformatics is discussed in Chapter 11. The complex nature of the subject and its interaction with other disciplines are outlined, and the inter-dependence of bioinformatics, the development of computer hardware and the internet is stressed. The nature and range of biological databases are outlined, from the inception of nucleic acid databases in the 1970s to the present breadth of primary and secondary databases that are repositories for information on nucleic acid and protein sequences, interactions between cellular components, biochemical pathways, pharmacological targets and many other data sets derived from existing information. Genome sequence databases are used to illustrate the tools needed to assemble, collate, annotate and interrogate the data, and the impact of bioinformatics in enabling experiments and protocols to to be conducted in silico is discussed.

  • Every Single Word: A New Data Set Including All Parliamentary Materials Published in Germany

  • Tobias Remschel, Corinna Kroeber
  • Journal:
    Government and Opposition / Volume 57 / Issue 2 / April 2022
    Published online by Cambridge University Press:
    22 December 2020, pp. 276-295
    Print publication:
    April 2022
    • Article
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      • Open access
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  • In this article, we introduce a unique data set containing all written communication published by the German Bundestag between 1949 and 2017. Increasing numbers of scholars make use of protocols of parliamentary speeches, parliamentary questions or the texts of legislative drafts in various fields of comparative politics including representation, responsiveness, professionalization and political careers or parliamentary agenda studies. Since preparing parliamentary documents is rather resource intensive, these studies remain limited to single points in time, types of documents and/or policy areas. The long time horizon and various types of documents covered by our new comprehensive data set will enable scholars interested in parliaments, parties and representatives to answer various innovative research questions related to legislative studies.