This article provides a retrospective on the formation of the Engaged Humanities Lab at Royal Holloway, University of London. It sets the lab’s development within the broader history of labs in the humanities, setting out how the Engaged Humanities Lab aligns closely with Pawlicka-Deger’s description of “infrastructure of engagement” rather than the physical spaces that characterise science laboratories. We also explain why the sub-category of “engaged” humanities was selected over the broader and more established “public” humanities. The second half of the article provides reflections on the activities and achievements of the Engaged Humanities Lab, focusing on how intra-institution collaboration between an academic school and the Research and Innovation Department supported the formation and governance of the lab, allowing for ongoing dialogue and co-creation between subject area experts and research management professionals with expertise in research funding, policy, and knowledge exchange. This article also illuminates what is needed from university leaders to ensure the success and longevity of infrastructures of engagement like the Engaged Humanities Lab.