Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
  1. Home
  2. Search

Refine search

Refine search

Access:
Content type:
Publication date:
Apply   From and To filters
Subject: Show more
Journals Show more
Publishers: Show more
Societies Show more
Series: Show more
Collections: Show more

Actions for selected content:

Select all | Deselect all
  • View selected items
  • Export citations
  • Download PDF (zip)
  • Save to Kindle
  • Save to Dropbox
  • Save to Google Drive

Save Search

You can save your searches here and later view and run them again in "My saved searches".

Please provide a title, maximum of 40 characters.
Cancel
×

4 results

  • The Sensitivity and Specificity of Split-Hand Index Using Muscle Sonography

  • Reuven Avidan, Yaara Fainmesser, Vivian E. Drory, Vera Bril, Alon Abraham
  • Journal:
    Canadian Journal of Neurological Sciences / Volume 50 / Issue 2 / March 2023
    Published online by Cambridge University Press:
    22 February 2022, pp. 228-233
    • Article
      • You have access
      • Open access
    • PDF
    • HTML
    • Export citation
  • Background:

    The split-hand index (SHI) (first dorsal interosseous (FDI) × abductor pollicis brevis (APB)/abductor digiti minimi muscle (ADM)) has been suggested as a useful measure for amyotrophic lateral sclerosis (ALS) diagnosis, using electrophysiological and sonographic indices. In the present study, we aimed to explore the specificity of SHI derived by muscle ultrasound (MUS) for the diagnosis of ALS and spinal muscular atrophy (SMA).

    Methods:

    Healthy controls (n = 65) were prospectively recruited at the Prosserman Family Neuromuscular clinic at Toronto General Hospital, from October to December 2018. In addition, 181 patients with ALS (n = 91), SMA (n = 33), polyneuropathy (n = 35), and myopathy (n = 22) were prospectively recruited at the neuromuscular clinic at Tel Aviv Sourasky Medical Center, from December 2018 to December 2020. All subjects underwent quantitative sonographic evaluation of muscle thickness, including the right APB, FDI, and ADM muscles. Area under curve (AUC), sensitivity, and specificity were determined for differentiating between groups.

    Results:

    Although SHI showed good to excellent accuracy for differentiating each patient subgroup from controls (AUC 0.83–0.92), poorer diagnostic accuracy was shown for differentiating between different patient subgroups (AUC 0.54–0.74).

    Conclusions:

    Sonographic SHI is useful for differentiating patients from healthy controls, but might be not specific for motor neuron disease.

  • Chapter 19 - Brecht’s Ethics

  • from Part II - Brecht’s Work
  • Edited by Stephen Brockmann, Carnegie Mellon University, Pennsylvania
  • Book:
    Bertolt Brecht in Context
    Published online:
    28 May 2021
    Print publication:
    10 June 2021, pp 166-173

  • Summary

    This article develops Brecht’s anti-metaphysical and materialist ethics through a close reading of “The Great Method,” a short text from his Me-ti that, in just three sentences, articulates a code of conduct for the revolutionary struggle. This article tries to show that even though “The Great Method” is based on the dialectics of Hegel, Marx, and Lenin, it also reflects Brecht’s interest in classical Chinese thought, in particular the Taoist notion of a subject’s full immersion in the situation requiring an ethical decision (Zhuangzi) and the assumption of an “efficacy that stems from disposition” (François Jullien), which, for example, underpins Brecht’s insistence on linguistic precision and use of modelbooks. This article also emphasizes the central role of production for Brecht’s ethics: “The Great Method” aims to unleash the human potential for productivity in all its forms, beyond capitalism, but is less interested in the production of things than in the production of change in things.

  • A Yin-Yang Model of Organizational Change: The Case of Chengdu Bus Group

  • Runtian Jing, Andrew H. Van de Ven
  • Journal:
    Management and Organization Review / Volume 10 / Issue 1 / March 2014
    Published online by Cambridge University Press:
    02 February 2015, pp. 29-54

  • The Chinese cultural logics of change offer a rich understanding of organizational change. We address three key aspects of the Chinese yin-yang view of change: context, process, and actions. A case study of Chengdu Bus Group CBG enables us to develop a conceptual model that examines organizational change in a Chinese indigenous context. The model reflects the key functions of shi (situational momentum, 势), the action strategies of ying-shi (leveraging momentum, 应势)and zao-shi (building momentum, 造势), and the dialectics of nonaction (无为). Our findings will help researchers and practitioners better understand organizational change from a unique yin-yang perspective, and will also contribute general knowledge to process theories of organizational change.

  • A short history of health technology assessment in Germany

  • Matthias Perleth, Bernhard Gibis, Britta Göhlen
  • Journal:
    International Journal of Technology Assessment in Health Care / Volume 25 / Issue S1 / July 2009
    Published online by Cambridge University Press:
    01 July 2009, pp. 112-119
    • Article
      • You have access
    • PDF
    • HTML
    • Export citation

  • Objectives: To provide an overview of the development of health technology assessment (HTA) in Germany since the 1990s.

    Methods: Analysis of key documents (e.g. literature, laws, and other official documentation) and personal experiences.

    Results: Health technology assessment (HTA) entered the political agenda in Germany only in the mid-1990s, basically as the result of a top-down approach toward more efficiency in health care, but with a strong impetus of an evidence-based medicine movement. Accordingly, HTA became part of several healthcare reform laws since 1997, which led to the establishment of the Federal Joint Committee (G-BA) and the Institute for Quality and Efficiency in Health Care (IQWiG) in 2004. This tandem construction aims at using evidence in decision-making processes for coverage and other decisions.

    Conclusions: These developments have led to a considerable impact of HTA in Germany. In addition, a broad spectrum of activities at universities and in other organizations, such as the German Institute for Medical Documentation and Information (DIMDI), can be observed that contribute to both teaching and research in HTA. German researchers in the field of HTA are actively involved in international projects, such as EUNetHTA, and contribute to scientific conferences and journals.