This article explores the prevalence of high-level political and bureaucratic corruption in postindependence Uganda, with particular focus on the narrow interests it serves and its impact on development and service delivery. It argues that high-level political corruption endures largely because it is situated within the framework of “neo”-patron-clientelism and skewed power relations. The article shows how institutions have not been able to effectively engage the inner-circle ruling elite due to a skewed power structure that serves narrow political interests. Grand bureaucratic and petty forms of corruption are equally extensive and challenging, though only the former have been affected by “zero tolerance” policies. The article concludes, however, that through its interplay of inclusion and exclusion, political corruption has generated contestations which undermine it and challenge the National Resistance Movement (NRM) regime.