We establish a conservation law for G/G/1 queues with any work-conserving service discipline using the equilibrium equations, also called the basic equations. We use this conservation law to prove an extremal property of the first-come firstserved (FCFS) service discipline: among all service disciplines that are work-conserving and independent of remaining service requirements for individual customers, the FCFS service discipline minimizes [maximizes] the mean sojourn time in a G/G/1 queue with independent (but not necessarily identical) service times with a common mean and new better [worse] than used (NBUE[NWUE]) distributions. This extends recent results of Halfin and Whitt (1990), Righter et al. (1990) and Yamazaki and Sakasegawa (1987a,b). In addition we use the conservation law to obtain an approximation for the mean queue length in a GI/GI/1 queue under the processor-sharing service discipline with finite degree of multiplicity, called LiPS discipline. Several numerical examples are presented which support the practical usefulness of the proposed approximation.