A new species of vesicomyid bivalve (Isorropodon nyeggaensis sp. nov.) is described based on shell morphology, from the Nyegga cold methane seep area on the Norwegian continental margin. This is the first description of vesicomyids from the Norwegian Sea and the northernmost record of recent representatives of the family Vesicomyidae. A dispersion of the genus into the Norwegian Sea basin from the north-eastern Atlantic is suggested. A brief description of other macrofauna from methane seep sites at Nyegga is also given.