In 2024, we are celebrating the 280th anniversary of Jean-Baptiste Lamarck, whose early theories on inheritance and environmental adaptation have advanced the foundational concepts of Developmental Origins of Health and Disease (DOHaD). This proposal aims to explore how some Lamarckian ideas align with contemporary understandings of how environmental factors in early life can affect health throughout an individual’s lifetime and across generations. This text not only honors an important historical milestone but also reflects on how a DOHaD notion might have been present since the earliest years of biological science. It bridges historical scientific thought with present-day scientific research.