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daz family

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1 results

Identification and expression analysis of Dazl homologue in Cynops cyanurus
Yinjiao Zhao, Ya Du, Qinglan Ge, Fang Yan, Shu Wei
Journal:

Zygote / Volume 30 / Issue 2 / April 2022

Published online by Cambridge University Press:

28 July 2021, pp. 221-226
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The Dazl (deleted in azoospermia-like) gene encodes an RNA-binding protein containing an RNA recognition motif (RRM) and a DAZ motif. Dazl is essential for gametogenesis in vertebrates. In this study, we report the cloning of Dazl cDNA from Cynops cyanurus. Ccdazl mRNA showed a germline-specific expression pattern as expected. Ccdazl expression gradually decreased during oogenesis, suggesting that it may be involved in oocyte development. Phylogenetic analysis revealed that the Ccdazl protein shares conserved motifs/domains with Dazl proteins from other species. Cloning of Ccdazl provides a new tool to carry out comparative studies of germ cell development in amphibians.