Acifluorfen, lactofen, chlorimuron, thifensulfuron, imazethapyr, and imazaquin were evaluated for control of Palmer amaranth, common waterhemp, redroot pigweed, and tumble pigweed at three application timings in field and greenhouse experiments. Results from field studies indicated that most herbicides provided greater than 90% control of common waterhemp, redroot pigweed, and tumble pigweed regardless of time of application. Palmer amaranth was the most difficult species to control, and only thifensulfuron and imazethapyr provided greater than 80% control at all application timings. In the greenhouse experiment, herbicides were applied when pigweeds averaged 10 cm, 20 cm, and 30 cm in height. Results were similar to the field experiment, except that common waterhemp was more difficult to control.