This article traces the evolution of Italian strategies for imperial expansion from the decades after unification—when many came to believe that imperial conquest would more advantageously position Italy in the liberal capitalist global economy—to the height of the fascist colonial project in the Horn of Africa—when the fascists tried to break with the liberal global economy and construct a new, radical mercantilist and corporatist empire. Taking inspiration from their predecessors, the fascist regime extracted capital, resources, and labor from Africans and Italians to finance its war against the Ethiopian empire and its colonization of the Horn. While the war temporarily stimulated Italian industry, employed hundreds of thousands of work-hungry Italians, and consolidated the regime’s many corporatist institutions, it drained Italy’s reserves and alarmed the Duce’s allies among Italy’s industrial and financial elite. The regime, thus, shifted strategies, focusing on reducing the cost of the empire by exploiting African workers, eliminating inefficient small enterprises, and creating vast concessions for Italian industrialists. Conquering new territories and markets, acquiring a variety of primary resources, and empowering industry, Mussolini and the radical mercantilist-corporatists aimed to resolve Italy’s perceived under-development, by placing Italy at the center of a great fascist Eurafrican empire that could dictate the terms of its engagement with the rest of the world.