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Quercetin: Nutritional and beneficial effects in poultry

Published online by Cambridge University Press:  20 April 2017

M. SAEED ,
M. NAVEED ,
M.A. ARAIN ,
M. ARIF ,
M.E. ABD EL-HACK ,
M. ALAGAWANY ,
F.A. SIYAL ,
R.N. SOOMRO  and
C. SUN
M. SAEED
Affiliation:
Department of Animal Nutrition, College of Animal Science and Technology, Northwest A&F University, Yangling Shaanxi 712100, P.R. China Institute of Animal Sciences, University of Agriculture Faisalabad, Pakistan38040
M. NAVEED
Affiliation:
Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu Province, 211198, China Faculty of Pharmacy and Alternative MedicineThe Islamia University of BahawalpurPakistan63100
M.A. ARAIN
Affiliation:
College of Animal Sciences and Technology, Northwest A&F University, Yangling 712100, China Faculty of Veterinary and Animal Sciences, Lasbela University of Agriculture Water and Marine Sciences Uthal, Pakistan, 3800
M. ARIF
Affiliation:
Department of Animal Sciences, College of Agriculture, University of Sargodha, Pakistan
M.E. ABD EL-HACK
Affiliation:
Department of Poultry, Faculty of Agriculture, Zagazig University, Zagazig, 44511, Egypt
M. ALAGAWANY*
Affiliation:
Department of Poultry, Faculty of Agriculture, Zagazig University, Zagazig, 44511, Egypt
F.A. SIYAL
Affiliation:
Department of Animal Nutrition, Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University Tando Jam, Pakistan70060
R.N. SOOMRO
Affiliation:
College of Animal Sciences and Technology, Northwest A&F University, Yangling 712100, China
C. SUN*
Affiliation:
College of Animal Sciences and Technology, Northwest A&F University, Yangling 712100, China
*
Corresponding authors: sunchao2775@163.com; dr.mahmoud.alagwany@gmail.com
Corresponding authors: sunchao2775@163.com; dr.mahmoud.alagwany@gmail.com
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Abstract

Flavonoids are natural compounds derived from fruits, vegetables and medicinal plants. These compounds have been reported to possess various biological actions including anti-inflammatory, antioxidant, growth promoter, antiviral, hepatoprotective, antibacterial, antiallergic, anticarcinogenic, antithrombotic and immunomodulator activities in various animals and poultry species. Quercetin is found in various foods such as vegetables, tea, fruits, wine apples and onions and is known to exert positive effects on poultry production and health. Since, quercetin enhances the immune system by stimulating lymphocytes, macrophages and IgY antibody production and improving natural killer cell activity, lymphoid organs (spleen, thymus and bursa) weights as well as activating the cytokines profile, its supplementation can lead to a state of immune alertness and a lower incidence of infections and diseases. In addition, it affects the dendritic cells (DCs) that play an important role in adaptive and innate immunity. Quercetin revokes the ability of lipopolysaccharide (LPS)-stimulated dendritic cells to induce specific T cell activation and reduce the cytotoxicity in both in vivo and in vitro studies, suggesting quercetin works as an immunosuppressive agent. As immune function is crucial for poultry productivity and prosperity, this review elucidates the potential nutritional effects and health benefits of quercetin on poultry as a replacer for traditional immune boosters and growth promoters. It includes the antiviral activity of quercetin against influenza A virus, rhinovirus (caused common cold), adenovirus (source of necrotic pancreatitis in broilers) and suggests its role in counteracting heavy metal toxicity. However, further studies on molecular basis are required to understand mode of action, beneficial applications as a natural feed additive, growth promoter and immune enhancer, beside the side effects of this compound in poultry.

Keywords

flavonoidsquercetinchemical structurebeneficial aspectshealthpoultry
Type
Reviews
Information
World's Poultry Science Journal , Volume 73 , Issue 2 , June 2017 , pp. 355 - 364
Copyright
Copyright © World's Poultry Science Association 2017 

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