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Mycoplasmosis in poultry: update on diagnosis and preventive measures

Published online by Cambridge University Press:  21 December 2016

S. UMAR ,
M.T. MUNIR ,
Z. UR-REHMAN ,
S. SUBHAN ,
T. AZAM  and
M.A.A. SHAH
S. UMAR*
Affiliation:
Department of Pathobiology PMAS Arid Agriculture University RawalpindiPakistan
M.T. MUNIR
Affiliation:
Nantes Atlantic National College of Veterinary Medicine, Food Science and Engineering (ONIRIS), Nantes, France
Z. UR-REHMAN
Affiliation:
Department of Poultry Science PMAS Arid Agriculture University RawalpindiPakistan
S. SUBHAN
Affiliation:
University of Veterinary & Animal Sciences LahorePakistan
T. AZAM
Affiliation:
University of Veterinary & Animal Sciences LahorePakistan
M.A.A. SHAH
Affiliation:
Department of Pathobiology PMAS Arid Agriculture University RawalpindiPakistan
*
Corresponding author: [email protected]
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Abstract

Avian mycoplasmas occur in a wide variety of birds including commercial poultry. The most important mycoplasmas in chickens and turkeys are Mycoplasma gallisepticum (MG), M. synoviae (MS), and M. meleagridis. Additionally, M. iowe (MI) is an emerging pathogen in turkeys, but appears to pose little issues for chickens. Pathogenic mechanisms include adherence to host target cells, release of toxins, mediation of apoptosis and immune evasion leading to obstruction of the tracheal lumen, exfoliation of epithelial cells as well as ciliostasis. In addition, mycoplasma by-products, such as hydrogen peroxide and superoxide radicals, along with inflammatory cytokines can exacerbate the disease conditions. Mycoplasmas are transmitted horizontally, from bird to bird, and vertically, from dam to offspring through the egg. The disease is diagnosed by serologic tests, cultures and PCR and is sensitive to antimicrobials whose activity is other than disrupting the bacterial cell wall. Control of pathogenic avian mycoplasmas can consist of one of three general approaches; maintaining flocks free of infection, medication, or vaccination, which are covered in this review.

Keywords

mycoplasmadiagnosispreventionvaccinationpoultry
Type
Reviews
Information
World's Poultry Science Journal , Volume 73 , Issue 1 , March 2017 , pp. 17 - 28
Copyright
Copyright © World's Poultry Science Association 2017 

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