Hostname: page-component-586b7cd67f-2brh9 Total loading time: 0 Render date: 2024-11-30T23:48:42.780Z Has data issue: false hasContentIssue false
  • English
  • Français

Campylobacter infections in poultry: update on challenges and potential immune interventions

Published online by Cambridge University Press:  26 April 2016

S. UMAR ,
A.T. MAIYAH  and
A. MUSHTAQ
S. UMAR*
Affiliation:
PMAS Arid Agriculture University, Rawalpindi, Pakistan National Veterinary School, Toulouse, France
A.T. MAIYAH
Affiliation:
University of Lampung, Indonesia
A. MUSHTAQ
Affiliation:
Veterinary Research Institute (VRI), Lahore, Pakistan
*
Corresponding author: [email protected]
Get access

Abstract

Poultry is frequently colonised by and constitutes a natural reservoir for Campylobacter spp., primarily C. jejuni and C. coli. Infection with C. jejuni is a leading cause of food borne gastroenteritis in humans worldwide. Prevalence rates in poultry are variable and can reach as high as 100% on some farms. Campylobacter spp. are commensal organisms that establish persistent infections which produce little or no overt disease in the avian host despite extensive colonisation. Although campylobacteriosis is insignificant for poultry health, contaminated poultry meat is recognised as the main source for human exposure. An alarming recent trend is the rapid emergence of antimicrobial resistant Campylobacter spp. strains all over the world. Colonisation can persist for the lifetime of the animal, consequently leading to carcass contamination at the slaughter facility. Therefore, considerable research efforts have been devoted to the development of interventions to diminish contamination in poultry, with the intention to reduce the burden of food borne illnesses. During the past decade, significant advances have been made in understanding Campylobacter spp. in poultry. This review summarises the currently available information about the infections in poultry. Secondly, it addresses the colonisation, risk factors and current challenges of Campylobacter spp. in poultry. Finally, immune intervention and the future prospects of vaccination for the control of Campylobacter spp. in poultry are discussed.

Keywords

Campylobacterpoultrycolonisationchallengesimmune interventions
Type
Reviews
Information
World's Poultry Science Journal , Volume 72 , Issue 2 , June 2016 , pp. 381 - 390
Copyright
Copyright © World's Poultry Science Association 2016 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

AGUNOS, A., WADDELL, L., LEGER, D. and TABOADA, E. (2014) A systematic review characterising on-farm sources of Campylobacter species for broiler chickens. PLoS One 9:e104905.Google Scholar
AL-ADWANI, S.R., CRESPO, R. and SHAH, D.H. (2013) Production and evaluation of chicken egg-yolk-derived antibodies against Campylobacter jejuni colonisation-associated proteins. Food borne Pathogens Diseases 10: 624-631.Google Scholar
ALLAIN, V., CHEMALY, M., LAISNEY, M.J., ROUXEL, S., QUESNE, S. and LE, B.S. (2014) Prevalence of and risk factors for Campylobacter colonisation in broiler flocks at the end of the rearing period in France. British Poultry Science 55: 452-459.Google Scholar
ALLEN, V.M., RIDLEY, A.M., HARRIS, J.A., NEWELL, D.G. and POWEL, L. (2011) Influence of production system on the rate of onset of Campylobacter colonisation in chicken flocks reared extensively in the United Kingdom. British Poultry Science 52: 30-39.Google Scholar
ANNAMALAI, T., PINA-MIMBELA, R., KUMAR, A., BINJAWADAGI, B., LIU, Z., RENUKARADHYA, G.J. and RAJASHEKARA, G. (2013) Evaluation of nano particle encapsulated outer membrane proteins for the control of Campylobacter jejuni colonisation in chickens. Poultry Science 92: 2201-2211.Google Scholar
AWAD, W.A., SMORODCHENKO, A., HESS, C., ASCHENBACH, J.R., MOLNAR, A., DUBLECZ, K., KHAYAL, B., POHL, E. and HESS, M. (2015) Increased intracellular calcium level and impaired nutrient absorption are important pathogenicity traits in the chicken intestinal epithelium during Campylobacter jejuni colonisation. Applied Microbiology and Biotechnology, doi: 10.1007/s00253-015-6543.Google Scholar
BAHRNDORFF, S., RANGSTRUP-CHRISTENSEN, L., NORDENTOFT, S. and HALD, B. (2013) Food borne disease prevention and broiler chickens with reduced Campylobacter infection. Emerging Infectious Diseases 19: 425-430.Google Scholar
BARRIOS, P.R., REIERSEN, J., LOWMAN, R., BISAILLON, J.R., MICHEL, P., FRIDRIKSDOTTIR, V., GUNNARSSON, E., STERN, N., BERKE, O., MCEWEN, S. and MARTIN, W. (2006) Risk factors for Campylobacter species colonisation in broiler flocks in Iceland. Preventive Veterinary Medicine 74: 264-278.Google Scholar
CAWTHRAW, S.A. and NEWELL, D.G. (2010) Investigation of the presence and protective effects of maternal antibodies against Campylobacter jejuni in chickens. Avian Diseases 54: 86-93.Google Scholar
CHALONER, G., WIGLEY, P., HUMPHREY, S., KEMMETT, K., LACHARME-LORA, L., HUMPHREY, T. and WILLIAMS, N. (2014) Dynamics of dual infection with Campylobacter jejuni strains in chickens reveals distinct strain-to-strain variation in infection ecology. Applied Environmental Microbiology 80: 6366-6372.CrossRefGoogle ScholarPubMed
CLARK, J.D., OAKES, R.D., REDHEAD, K., CROUCH, C.F., FRANCIS, M.J., TOMLEY, F.M. and BLAKE, D.P. (2012) Eimeria species parasites as novel vaccine delivery vectors: Anti-Campylobacter jejuni protective immunity induced by Eimeria tenella-delivered CjaA. Vaccine 30: 2683-2688.Google Scholar
CONNELL, S., MEADE, K.G., ALLAN, B., LLOYD, A.T., KENNY, E., CORMICAN, P., MORRIS, D.W., BRADLEY, D.G. and O'FARRELLY, C. (2012) Avian resistance to Campylobacter jejuni colonisation is associated with an intestinal immunogene expression signature identified by mRNA sequencing. PLoS One 7 (8): e40409.Google Scholar
DE ZOETE, M.R., VAN PUTTEN, J.P. and WAGENAAR, J.A. (2007) Vaccination of chickens against Campylobacter. Vaccine 25: 5548-5557.CrossRefGoogle ScholarPubMed
ELLIS-IVERSEN, J., RIDLEY, A., MORRIS, V., SOWA, A., HARRIS, J., ATTERBURY, R., SPARKS, N. and ALLEN, V. (2012) Persistent environmental reservoirs on farms as risk factors for Campylobacter in commercial poultry. Epidemiology and Infection 140: 916-924.Google Scholar
ELVERS, K.T., MORRIS, V.K., NEWELL, D.G. and ALLEN, V.M. (2011) Molecular tracking, through processing, of Campylobacter strains colonising broiler flocks. Applied Environmental Microbiology 77: 5722-5729.CrossRefGoogle ScholarPubMed
EFSA (2011) Scientific opinion on Campylobacter in broiler meat production: control options and performance objectives and/or targets at different stages of the food chain. EFSA Journal 9:2105.Google Scholar
GARCIA, A.B., BAHRNDORFF, B., HALD, B., HOORFAR, J., MADSEN, M. and VIGRE, H. (2012) Design and data analysis of experimental trials to test vaccine candidates against zoonotic pathogens in animals: the case of a clinical trial against Campylobacter in broilers. Expert Review of Vaccines 11: 1179-1188.Google Scholar
GORMLEY, F.J., BAILEY, R.A., WATSON, K.A., MCADAM, J., AVENDANO, S., STANLEY, W.A. and KOERHUIS, A.N. (2014) Campylobacter colonisation and proliferation in the broiler chicken upon natural field challenge is not affected by the bird growth rate or breed. Applied Environmental Microbiology 80: 6733-6738.Google Scholar
GUERIN, M.T., SIR, C., SARGEANT, J.M., WADDELL, L., O'CONNOR, A.M., WILLS, R.W., BAILEY, R.H. and BYRD, J.A. (2010) The change in prevalence of Campylobacter on chicken carcasses during processing: a systematic review. Poultry Science 89: 1070-1084.Google Scholar
HERMANS, D., PASMANS, F., HEYNDRICKX, M., VAN IMMERSEEL, F., VAN DEUN, K. and HAESEBROUCK, F. (2011) A tolerogenic mucosal immune response leads to persistent Campylobacter jejuni colonisation in the chicken gut. Critical Review of Microbiology 38: 17-29.Google Scholar
HERMANS, D., PASMANS, F., MESSENS, W., MARTEL, A., VAN IMMERSEEL, F., RASSCHAERT, G., HEYNDRICKX, M., VAN DEUN, K. and HAESEBROUCK, F. (2012) Poultry as a host for the zoonotic pathogen Campylobacter jejuni. Vector-Borne Zoonotic Diseases 12: 89-98.CrossRefGoogle ScholarPubMed
HERMANS, D., VAN STEENDAM, K., VERBRUGGHE, E., VERLINDEN, M., MARTEL, A., SELIWIORSTOW, T., HEYNDRICKX, M., HAESEBROUCK, F., DE ZUTTER, L., DEFORCE, D. and PASMANS, F. (2014) Passive immunisation to reduce Campylobacter jejuni colonisation and transmission in broiler chickens. Veterinary Research 45: 27.Google Scholar
HU, Y.Q., HUANG, J.L. and JIAO, X.A. (2014) Screening of genes expressed in vivo during interaction between chicken and Campylobacter jejuni. Journal of Microbiology and Biotechnology 24: 217-224.Google Scholar
HUMPHREY, S., CHALONER, G., KEMMETT, K., DAVIDSON, N., WILLIAMS, N., KIPAR, A., HUMPHREY, T. and WIGLEY, P. (2014) Campylobacter jejuni is not merely a commensal in commercial broiler chickens and affects bird welfare. mBio 5: e01364-14.Google Scholar
HUANG, J.L., YIN, Y.X., PAN, Z.M., ZHANG, G., ZHU, A.P., LIU, X.F. and JIAO, X.A. (2010) Intranasal immunisation with chitosan/pCAGGS-flaA nanoparticles inhibits Campylobacter jejuni in a white leghorn model. Journal of Biomedicine and Biotechnology doi: 10.1155/2010/589476.CrossRefGoogle Scholar
JENNINGS, J.L., SAIT, L.C., PERRETT, C.A., FOSTER, C., WILLIAMS, L.K., HUMPHREY, T.J. and COGAN, T.A. (2011) Campylobacter jejuni is associated with, but not sufficient to cause vibrionic hepatitis in chickens. Veterinary Microbiology 149: 193-199.Google Scholar
LANIEWSKI, P., KUCZKOWSKI, M., CHRZASTEK, K., WOZNIAK, A., WYSZYNSKA, A., WIELICZKO, A. and JAGUSZTYN-KRYNICKA, E.K. (2014) .Evaluation of the immunogenicity of Campylobacter jejuni CjaA protein delivered by Salmonella enteric sv. Typhimurium strain with regulated delayed attenuation in chickens. World Journal of Microbiology and Biotechnology 30: 281-292.Google Scholar
LIN, J. (2009) Novel approaches for Campylobacter control in poultry. Food borne Pathogens and Disease 6: 755-765.Google Scholar
PAUL, N.C., AL-ADWANI, S., CRESPO, R. and SHAH, D.H. (2014) Evaluation of passive immunotherapeutic efficacy of hyperimmunised egg yolk powder against intestinal colonisation of C. jejuni in chickens. Poultry Science 93: 2779-2787.Google Scholar
RIAZI, A., STRONG, P.C.R., COLEMAN, R., CHEN, W., HIRAMA, T., VAN FAASSEN, H., HENRY, M., LOGAN, S.M., SZYMANSKI, C.M., MACKENZIE, R. and GHAHROUDI, M.A. (2013) Pentavalent single-domain antibodies reduce Campylobacter jejuni motility and colonisation in chickens. PLoS One 8: e83928.CrossRefGoogle ScholarPubMed
RIDLEY, A., MORRIS, V., GITTINS, J., CAWTHRAW, S., HARRIS, J., EDGE, S. and ALLEN, V. (2011) Potential sources of Campylobacter infection on chicken farms: contamination and control of broiler-harvesting equipment, vehicles and personnel. Journal of Applied Microbiology 111: 233-244.Google Scholar
SAHIN, O., KOBALKA, P. and ZHANG, Q. (2003) Detection and survival of Campylobacter in chicken eggs. Journal of Applied Microbiology 95: 1070-1079.Google Scholar
SAHIN, O., KASSEM, I.I., SHEN, Z., LIN, J., RAJASHEKARA, G. and ZHAN, Q. (2015) Campylobacter in Poultry: Ecology and Potential Interventions. Avian Diseases 59: 185-200.Google Scholar
SCALLAN, E., HOEKSTRA, R.M., ANGULO, F.J., TAUXE, R.V., WIDDOWSON, M.A., ROY, S.L., JONES, J.L. and GRIFFIN, P.M. (2011) Food borne illness acquired in the United States major pathogens. Emerging Infectious Diseases 17: 7-15.Google Scholar
THEORET, J.R., COOPER, K.K., ZEKARIAS, B., ROLAND, K.L., LAW, B.F., CURTISS, R. and JOENS, L.A. (2012) The Campylobacter jejuni Dps homologue is important for in vitro biofilm formation and caecal colonisation of poultry and may serve as a protective antigen for vaccination. Clinical and Vaccine Immunology 19: 1426-1431.Google Scholar
UMARAW, P., PRAJAPATI, A., VERMA, A.K., VERMA, K., V. PATHAK, V. and SINGH, V.P. (2015) Control of Campylobacter in Poultry Industry from Farm to Poultry Processing Unit: A Review. Critical Reviews in Food Science and Nutrition DOI: 10.1080/10408398.2014.935847.Google Scholar
WEI, B., CHA, S.Y., KANG, M., ROH, J.H., SEO, H.S., YOON, R.H. and JANG, H.K. (2014) Antimicrobial susceptibility profiles and molecular typing of Campylobacter jejuni and Campylobacter coli isolated from ducks in South Korea. Applied Environmental Microbiology doi: 10.1128/AEM.02469-14.Google Scholar
WIGLEY, P. (2013) Immunity to bacterial infection in the chicken. Developmental Comparative Immunology 41: 413-417.Google Scholar
WILLIAMS, L.K., SAIT, L.C., TRANTHAM, E.K., COGAN, T.A. and HUMPHREY, T.J. (2013) Campylobacter infection has different outcomes in fast- and slow-growing broiler chickens. Avian Diseases 57: 238-241.Google Scholar
YEH, H.Y., HIETT, K.L., LINE, J.E. and SEAL, B.S. (2014) Characterisation and reactivity of broiler chicken sera to selected recombinant Campylobacter jejuni chemotactic proteins. Achieves of Microbiology 196: 375-383.Google Scholar
ZHANG, Q., SAHIN, O., SWAYNE, D.E., GLISSON, J.R., MCDOUGALD, L.R., NOLAN, L.K., SUAREZ, D.L. and NAIR, V.L. (2013) Campylobacteriosis, in: Diseases of poultry, 13th ed., pp. 737-750 (John Wiley & Sons, Inc., Ames, IA).Google Scholar