The herbicide 2,4-D has been in commerce and a subject for research since 1944. It is undoubtedly among the most thoroughly researched pesticides in the world. In our society, 2,4-D has played an indispensable role. It is most important in the production of our food and fiber; in the control of noxious weeds causing public health problems such as common ragweed (Ambrosia artemisiifolia L.) and poison-ivy [Toxicodendron radicans (L.) Ktze.] in the maintenance of our utility supply lines and highway and railroad systems; and as a useful tool for creating desirable wildlife habitats and beautifying our parks, golf courses, and the grounds about our homes.
Recently completed toxicological studies support the conclusions of earlier studies that 2,4-D may be used without undue risk to man, wildlife, or the environment. This does not mean, of course, that we should lessen our precautions to avoid exposure to applicators, prevent spray drift from getting on bystanders, or on pets such as dogs and cats, and following general good sanitation practices in its use.
There have been some reports of an association between the use of 2,4-D and NHL. However, in our opinion after considering all the toxicological and epidemiological evidence, it has not been established that the use of 2,4-D causes NHL or any other type of cancer including soft tissue sarcomas and Hodgkin's disease. As cited in this review, most scientific experts who have carefully examined all the data share this opinion.