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Electrophysiological estimates of visual sensitivity in albino and pigmented mice

Published online by Cambridge University Press:  02 June 2009

Daniel G. Green ,
Pilar Herreros De Tejada  and
Marilyn J. Glover
Daniel G. Green
Affiliation:
Department of Ophthalmology, University of Michigan, Ann Arbor
Pilar Herreros De Tejada
Affiliation:
Departamento de Psicobiologia, Universidad Complutense de Madrid, Madrid, Spain
Marilyn J. Glover
Affiliation:
Department of Ophthalmology, University of Michigan, Ann Arbor
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Abstract

We have estimated the absolute threshold of congenic albino and pigmented mice (C57) using ERG, pupillary light reflex, and VHP. We are unable to detect strain differences using ERGs or VEPs, but pupillary thresholds appear to be different. In addition, as we have previously reported for rats, VEP thresholds are considerably lower than the ERG b−wave thresholds. The VEP thresholds agree with behavioral data from pigmented mice made by others. The mouse VEP thresholds are close to the VEP thresholds in rats and the psychophysical thresholds of two human observers.

Keywords

AlbinoPigmentedMouseElectroretinogramEvoked potentialAbsolute threshold
Type
Research Articles
Information
Visual Neuroscience , Volume 11 , Issue 5 , September 1994 , pp. 919 - 925
Copyright
Copyright © Cambridge University Press 1994

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