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Management of Twin–Twin Transfusion Syndrome: Laying the Foundation for Future Interventional Studies

Published online by Cambridge University Press:  21 February 2012

Anthony O. Odibo*
Affiliation:
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Pennsylvania Health System, Philadelphia, USA. [email protected]
George A. Macones
Affiliation:
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Pennsylvania Health System, Philadelphia, USA.
*
*Address for correspondence: Anthony Odibo, Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Pennsylvania Health System 2000 Courtyard, 3400 Spruce Street, Philadelphia PA 19104, USA.

Abstract

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Twin–twin transfusion syndrome is the most common complication of monochorionic pregnancies affecting between 5 and 15% of such pregnancies and accounts for 15–77% of perinatal mortality in twins. The management of twin–twin transfusion syndrome is complex and various treatment modalities have been tried. This review critically evaluates the different management options available for the syndrome and recommends some guidelines for future interventional studies.

Type
Articles
Copyright
Copyright © Cambridge University Press 2002