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Characteristics of a Japanese Adult Twin Database of High School Graduates

Published online by Cambridge University Press:  21 February 2012

Syuichi Ooki ,
Yuji Okazaki  and
Akio Asaka
Syuichi Ooki*
Affiliation:
Department of Health Science, Ishikawa Prefectural Nursing University, Kahoku, Ishikawa, Japan. [email protected]
Yuji Okazaki
Affiliation:
Department of Psychiatry, School of Medicine, Mie University, Tsu, Mie, Japan.
Akio Asaka
Affiliation:
Joto Hospital, Joto Kofu, Yamanashi, Japan.
*
*Address for correspondence: Syuichi Ooki, Department of Health Science, Ishikawa Prefectural Nursing University, Tsu7-1 Nakanuma, Kahoku, Ishikawa, 929-1212, Japan.

Abstract

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This paper profiles a unique cohort of adult Japanese twins. The database contains more than 700 twin pairs, aged 18 to 66 years, who are all graduates of the secondary school attached to the faculty of education of the University of Tokyo. This school was established in 1948, when the study of twins was burgeoning in Japan, and about 10 to 20 pairs of twins have been admitted there every year to participate in studies on twins in education and in related projects. The zygosity of all twins was determined carefully on the basis of various sources. Data from the perinatal period to adulthood were linkable using ID numbers. Follow-up surveys in the field of medical genetics were performed in 1985, 1989 and 1999. For the third survey, which was sent and received exclusively by mail, the distribution and collection process was also assessed in detail. The response rate was around 40%, which statistically was influenced mainly by previous participation and sex. The limitation of this cohort is its selection bias concerning socioeconomic status and its imbalance in favor of monozygotic pairs.

Type
Articles
Information
Twin Research and Human Genetics , Volume 7 , Issue 5 , 01 October 2004 , pp. 430 - 434
Copyright
Copyright © Cambridge University Press 2004