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Hereditary Factors in Sleepwalking and Night Terrors

Published online by Cambridge University Press:  29 January 2018

Anthony Kales ,
Constantin R. Soldatos ,
Edward O. Bixler ,
Roger L. Ladda ,
Dennis S. Charney ,
Gary Weber  and
Paula K. Schweitzer
Anthony Kales
Affiliation:
Department of Psychiatry, and Director, Sleep Research and Treatment Center, Pennsylvania State University School of Medicine, Hershey, Pennsylvania 17033, USA
Constantin R. Soldatos
Affiliation:
Department of Psychiatry and Sleep Research and Treatment Center, Pennsylvania State University School of Medicine
Edward O. Bixler
Affiliation:
Department of Psychiatry and Sleep Research and Treatment Center, Pennsylvania State University School of Medicine
Roger L. Ladda
Affiliation:
Department of Pediatrics, Pennsylvania State University School of Medicine
Dennis S. Charney
Affiliation:
Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
Gary Weber
Affiliation:
Pennsylvania State University School of Medicine
Paula K. Schweitzer
Affiliation:
Department of Psychiatry, Pennsylvania State University School of Medicine
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Summary

The families of 25 probands with sleepwalking and 27 probands with night terrors were studied. Eighty per cent of the sleepwalking pedigrees and 96 per cent of the night terror pedigrees included one or more individuals, other than the proband, who were affected by sleepwalking, night terrors, or both. Our data appear to fit a ‘two threshold’ multifactorial mode of inheritance. This finding supports the hypothesis that sleepwalking and night terrors share a common genetic predisposition, with sleepwalking being a more prevalent and less severe manifestation of the same substrate that underlies night terrors. Heritable factors predispose an individual to develop sleepwalking and/or night terrors, but expression of the trait may be influenced by environmental factors.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 137 , Issue 2 , August 1980 , pp. 111 - 118
Copyright
Copyright © Royal College of Psychiatrists, 1980 

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References

Abe, K. & Shimakawa, M. (1966) Predisposition to sleepwalking. Psychiatric Neurologic und Medizinsche Psychologic (Basel), 152, 306–12.Google ScholarPubMed
Bakwin, H. (1970) Sleepwalking in twins. The Lancet, ii, 446–7.Google Scholar
Bixler, E. O., Kales, A., Soldatos, C. R., Kales, J. D. & Healey, S. (1979) Prevalence of sleep disorders in the Los Angeles metropolitan area. American Journal of Psychiatry, 136, 1257–62.Google Scholar
Broughton, R. (1968) Sleep disorders: disorders of arousal? Science, 159, 1070–8.CrossRefGoogle ScholarPubMed
Carter, C. O. (1976) Genetics of common single malformations. British Medical Bulletin, 32, 21–6.CrossRefGoogle ScholarPubMed
Cloninger, C. R., Christiansen, K. O., Reich, T. & Gottesman, I. I. (1978) Implications of sex differences in the prevalences of antisocial personality, alcoholism, and criminality for familial transmission. Archives of General Psychiatry, 35, 941–51.Google Scholar
Edwards, J. H. (1969) Familial predisposition in man. British Medical Bulletin, 25, 58–64.Google Scholar
Falconer, D. S. (1965) The inheritance of liability to certain diseases, estimated from the incidence among relatives. Annals of Human Genetics, 29, 51–71.Google Scholar
Fisher, C., Kahn, E., Edwards, A. & Davis, D. (1973) A psychophysiological study of nightmares and night terrors. I. Physiological aspects of the stage 4 night terror. Journal of Nervous and Mental Disease, 157, 75–98.Google Scholar
Fisher, R. A. (1934) The effects of methods of ascertainment upon the estimation of frequencies. Annals of Eugenics (Lond.), 6, 13–25.CrossRefGoogle Scholar
Gastaut, H. & Broughton, R. (1965) A clinical and polygraphic study of episodic phenomena during sleep. Biological Psychiatry, 7, 197–221.Google Scholar
Hallstrom, R. (1972) Night terror in adults through three generations. Acta Psychiatrica Scandinavica, 48, 350–2.Google Scholar
Jacobson, A. & Kales, A. (1967) Somnambulism: All-night EEG and related studies. In Sleep and Altered States of Consciousness, pp 424–455. Baltimore: The Williams and Wilkins Company.Google Scholar
Kales, A., Jacobson, A., Paulson, J., Kales, J. D. & Walter, R. (1966) Somnambulism: psychophysiological correlates. I. All-night EEG studies. Archives of General Psychiatry, 14, 586–94.Google Scholar
Kales, J. D., Davis, R., Russek, E., Martin, E. D., Kuhn, W. & Kales, A. (1978a) Clinical characteristics of patients with night terrors: further studies. Sleep Research, 7, 191.Google Scholar
Kales, J. D., Humphrey, F. J., Martin, E. D., Russek, E., Kuhn, W., Pelicci, L. & Kales, A. (1978b) Clinical characteristics of patients with sleepwalking: further studies. Sleep Research, 7, 192.Google Scholar
Kessler, S., Guilleminault, C. & Dement, W. (1974) A family study of 50 REM narcoleptics. Acta Neurologica Scandinavica, 50, 503–12.Google ScholarPubMed
Kleitman, N. (1963) Sleep and Wakefulness. Chicago: University of Chicago Press.Google Scholar
Leckman, J. F. & Gershon, E. S. (1976) A genetic model of narcolepsy. British Journal of Psychiatry, 128, 276–9.CrossRefGoogle ScholarPubMed
Reich, T., James, J. W., & Morris, C. A. (1972) The use of multiple thresholds in determining the mode of transmission of semi-continuous traits. Annals of Human Genetics (Lond.), 36, 163–84.Google Scholar
Reich, T., Rice, J., Cloninger, C. R., Wette, R. & James, J. (1979) The use of multiple thresholds and segregation analysis in analyzing the phenotypic heterogeneity of multifactorial traits. Annals of Human Genetics (Lond.), 42, 371–90.Google ScholarPubMed
Shirley, A. F. & Kahn, J. P. (1958) Sleep disturbances in children. Pediatric Clinics of North America, 5, 629–43.CrossRefGoogle ScholarPubMed
Thomas, C. & Pederson, L. (1963) Psychobiological studies: Sleep habits of healthy young adults with observations on levels of cholesterol and circulating eosinophils. Journal of Chronic Diseases, 16, 1099–114.Google Scholar
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