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The effect of sarcopenic obesity on cardiovascular disease and all-cause mortality in older people

Published online by Cambridge University Press:  29 April 2015

Janice L Atkins  and
S Goya Wannamethee
Janice L Atkins*
Affiliation:
Department of Primary Care and Population Health, University College London, London, UK
S Goya Wannamethee
Affiliation:
Department of Primary Care and Population Health, University College London, London, UK
*
Address for correspondence: Mrs JL Atkins, Department of Primary Care and Population Health, University College London Medical School, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK. Email: [email protected]
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Summary

Obesity is a major public health problem with increasing prevalence worldwide. It is well recognized as a risk factor for cardiovascular morbidity and mortality in adult populations. Obesity prevalence is also increasing with age, and this may be particularly important in an ageing population. Ageing is associated with an increase in visceral fat and a progressive loss of muscle mass. Sarcopenia has been defined as the age-associated loss of skeletal muscle mass and has been associated with metabolic impairment, cardiovascular disease (CVD) risk factors, physical disability and mortality. Sarcopenia is often associated with obesity. Sarcopenic obesity is a new category of obesity in older adults who have high adiposity coupled with low muscle mass. Thus sarcopenia with obesity may synergistically increase their effect on metabolic disorders, CVD and mortality. This review focuses on the effects of sarcopenic obesity on the risk of cardiovascular disease and mortality in older adults.

Keywords

obesitymusclesarcopeniacardiovascular diseasemortalityolder adults
Type
Review Article
Information
Reviews in Clinical Gerontology , Volume 25 , Issue 2 , May 2015 , pp. 86 - 97
Copyright
Copyright © Cambridge University Press 2015 

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