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Hypothyroidism in patients treated with lithium: a review and two case reports

Published online by Cambridge University Press:  09 July 2009

M. J. Crowe ,
G. G. Lloyd ,
S. Bloch  and
R. M. Rosser
M. J. Crowe
Affiliation:
From the Bethlem Royal and Maudsley Hospitals, Denmark Hill, London
G. G. Lloyd
Affiliation:
From the Bethlem Royal and Maudsley Hospitals, Denmark Hill, London
S. Bloch
Affiliation:
From the Bethlem Royal and Maudsley Hospitals, Denmark Hill, London
R. M. Rosser
Affiliation:
From the Bethlem Royal and Maudsley Hospitals, Denmark Hill, London
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Synopsis

Two different types of hypothyroidism can occur during lithium administration, one with evidence of underlying thyroiditis, the other without. Two cases are reported, one of type 1, the other of type 2, and 17 other cases of lithium-induced hypothyroidism in the literature are reviewed. The literature on the occurrence of goitre during lithium treatment, and that on the alteration of thyroid function tests are also reviewed. Possible mechanisms for the disturbance of thyroid function are discussed and recommendations for managing this complication of lithium therapy are made.

Type
Research Article
Information
Psychological Medicine , Volume 3 , Issue 3 , August 1973 , pp. 337 - 342
Copyright
Copyright © Cambridge University Press 1973

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References

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