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Prospective study of risk factors for suicidal behavior in individuals with anxiety disorders

Published online by Cambridge University Press:  09 November 2012

L. A. Uebelacker ,
R. Weisberg ,
M. Millman ,
S. Yen  and
M. Keller
L. A. Uebelacker*
Affiliation:
Department of Psychiatry and Human Behavior Department of Family Medicine, Warren Alpert Medical School of Brown University, Providence, USA
R. Weisberg
Affiliation:
Department of Psychiatry and Human Behavior Department of Family Medicine, Warren Alpert Medical School of Brown University, Providence, USA
M. Millman
Affiliation:
Department of Psychiatry and Human Behavior Department of Family Medicine, Warren Alpert Medical School of Brown University, Providence, USA
S. Yen
Affiliation:
Department of Psychiatry and Human Behavior Department of Family Medicine, Warren Alpert Medical School of Brown University, Providence, USA
M. Keller
Affiliation:
Department of Psychiatry and Human Behavior Department of Family Medicine, Warren Alpert Medical School of Brown University, Providence, USA
*
*Address for correspondence: L. A. Uebelacker, Ph.D., Assistant Professor (Research), Psychosocial Research Program, Butler Hospital, 345 Blackstone Blvd, Providence, RI 02906, USA. (Email: [email protected])
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Abstract

Background

Anxiety disorders are very common and increase risk for suicide attempts. Little is known about predictors of increased risk specifically among individuals with anxiety disorders. The purpose of this study was to investigate whether specific anxiety disorders and other co-morbid psychiatric disorders, physical health, or work or social functioning increased the future likelihood of a suicide attempts among individuals with anxiety disorders.

Method

In this prospective study, 676 individuals with an anxiety disorder were followed for an average of 12 years.

Results

As hypothesized, we found that post-traumatic stress disorder, major depressive disorder (MDD), intermittent depressive disorder (IDD), epilepsy, pain, and poor work and social functioning all predicted a shorter time to a suicide attempt in univariate analyses. In multivariate analyses, baseline MDD and IDD were independent predictors of time to suicide attempt, even when controlling for a past history of suicide attempt. No specific anxiety disorder was an independent predictor of time to attempt in this anxiety-disordered sample. Adding baseline physical health variables and social functioning did not improve the ability of the model to predict time to suicide attempt.

Conclusions

Mood disorders and past history of suicide attempts are the most powerful predictors of a future suicide attempt in this sample of individuals, all of whom have an anxiety disorder.

Keywords

Anxiety disorderssuicidesuicide attempts
Type
Original Articles
Information
Psychological Medicine , Volume 43 , Issue 7 , July 2013 , pp. 1465 - 1474
Copyright
Copyright © Cambridge University Press 2012 

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