Hostname: page-component-78c5997874-t5tsf Total loading time: 0 Render date: 2024-11-05T06:39:29.927Z Has data issue: false hasContentIssue false

9/11-related PTSD among highly exposed populations: a systematic review 15 years after the attack

Published online by Cambridge University Press:  14 August 2017

A. Lowell
Affiliation:
Department of Psychiatry, Columbia University Medical Center, New York, NY, USA New York State Psychiatric Institute, New York, NY, USA
B. Suarez-Jimenez
Affiliation:
Department of Psychiatry, Columbia University Medical Center, New York, NY, USA New York State Psychiatric Institute, New York, NY, USA
L. Helpman
Affiliation:
Department of Psychiatry, Columbia University Medical Center, New York, NY, USA New York State Psychiatric Institute, New York, NY, USA
X. Zhu
Affiliation:
Department of Psychiatry, Columbia University Medical Center, New York, NY, USA New York State Psychiatric Institute, New York, NY, USA
A. Durosky
Affiliation:
New York State Psychiatric Institute, New York, NY, USA
A. Hilburn
Affiliation:
New York State Psychiatric Institute, New York, NY, USA
F. Schneier
Affiliation:
Department of Psychiatry, Columbia University Medical Center, New York, NY, USA New York State Psychiatric Institute, New York, NY, USA
R. Gross
Affiliation:
Department of Epidemiology, Columbia University Medical Center, New York, NY, USA Department of Epidemiology and Preventive Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel Division of Psychiatry, Chaim Sheba Medical Center, Tel Hashomer, Israel
Y. Neria*
Affiliation:
Department of Psychiatry, Columbia University Medical Center, New York, NY, USA New York State Psychiatric Institute, New York, NY, USA Department of Epidemiology, Columbia University Medical Center, New York, NY, USA
*
*Address for correspondence: Y. Neria, Ph.D., Department of Psychiatry, New York State Psychiatric Institute, College of Physicians and Surgeons, Columbia University, Unit #69,1051 Riverside Drive, New York, NY 10032, USA. (Email: [email protected])

Abstract

Background

The 11 September 2001 (9/11) attacks were unprecedented in magnitude and mental health impact. While a large body of research has emerged since the attacks, published reviews are few, and are limited by an emphasis on cross-sectional research, short time frame, and exclusion of treatment studies. Additionally, to date, there has been no systematic review of available longitudinal information as a unique data set. Consequently, knowledge regarding long-term trajectories of 9/11-related post-traumatic stress disorder (PTSD) among highly exposed populations, and whether available treatment approaches effectively address PTSD within the context of mass, man-made disaster, remains limited.

Methods

The present review aimed to address these gaps using a systematic review of peer-reviewed reports from October 2001 to May 2016. Eligible reports were of longitudinal studies of PTSD among highly exposed populations. We identified 20 reports of 9/11-related PTSD, including 13 longitudinal prevalence studies and seven treatment studies.

Results

Findings suggest a substantial burden of 9/11-related PTSD among those highly exposed to the attack, associated with a range of sociodemographic and back-ground factors, and characteristics of peri-event exposure. While most longitudinal studies show declining rates of prevalence of PTSD, studies of rescue/recovery workers have documented an increase over time. Treatment studies were few, and generally limited by methodological shortcomings, but support exposure-based therapies.

Conclusion

Future directions for research, treatment, and healthcare policy are discussed.

Type
Review Article
Copyright
Copyright © Cambridge University Press 2017 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Adams, RE, Boscarino, JA (2006). Predictors of PTSD and delayed PTSD after disaster: the impact of exposure and psychosocial resources. The Journal of Nervous and Mental Disease 194, 485493.Google Scholar
Andrews, B, Brewin, CR, Philpott, R, Stewart, L (2007). Delayed-onset posttraumatic stress disorder: a systematic review of the evidence. American Journal of Psychiatry 164, 13191326.Google Scholar
Berger, W, Coutinho, ESF, Figueira, I, Marques-Portella, C, Luz, MP, Neylan, TC, Marmar, CR, Mendlowicz, MV (2012). Rescuers at risk: a systematic review and meta-regression analysis of the worldwide current prevalence and correlates of PTSD in rescue workers. Social Psychiatry and Psychiatric Epidemiology 47, 10011011.Google Scholar
Berninger, A, Webber, MP, Cohen, HW, Gustave, J, Lee, R, Niles, JK, Chiu, S, Zeig-Owens, R, Soo, J, Kelly, K, Prezant, DJ et al. (2010a). Trends of elevated PTSD risk in firefighters exposed to the World Trade Center disaster: 2001-2005. Public Health Reports 125, 556566.Google Scholar
Berninger, A, Webber, MP, Niles, JK, Gustave, J, Lee, R, Cohen, HW, Kelly, K, Corrigan, M, Prezant, DJ (2010 b). Longitudinal study of probable post-traumatic stress disorder in firefighters exposed to the World Trade Center disaster. American Journal of Industrial Medicine 53, 11771185 (http://www.ncbi.nlm.nih.gov/pubmed/20862700).Google Scholar
Bills, CB, Levy, NAS, Sharma, V, Charney, DS, Herbert, R, Moline, J, Katz, CL (2008). Mental health of workers and volunteers responding to events of 9/11: review of the literature. The Mount Sinai Journal of Medicine 75, 173–115–127.Google Scholar
Blake, DD, Weathers, FW, Nagy, LM, Kaloupek, DG, Gusman, FD, Charney, DS, Keane, TM (1995). The development of a clinician-administered PTSD scale. Journal of Traumatic Stress 8, 7590 (http://www.ncbi.nlm.nih.gov/pubmed/7712061).Google Scholar
Blanchard, EB, Jones-Alexander, J, Buckley, TC, Forneris, CA (1996). Psychometric properties of the PTSD checklist (PCL). Behaviour Research and Therapy 34, 669673.Google Scholar
Bowler, RM, Harris, M, Li, J, Gocheva, V, Stellman, SD, Wilson, K, Alper, H, Schwarzer, R, Cone, JE (2012). Longitudinal mental health impact among police responders to the 9/11 terrorist attack. American Journal of Industrial Medicine 55, 297312.Google Scholar
Brackbill, RM, Hadler, JL, DiGrande, L, Ekenga, CC, Farfel, MR, Friedman, S, Perlman, SE, Stellman, SD, Walker, DJ, Wu, D, Yu, S, Thorpe, LE (2009). Asthma and posttraumatic stress symptoms 5 to 6 years following exposure to the World Trade Center terrorist attack. JAMA 302, 502516.Google Scholar
Brennstuhl, MJ, Tarquinio, C, Montel, S (2015). Chronic pain and PTSD: evolving views on their comorbidity. Perspectives in Psychiatric Care 51, 295304.Google Scholar
Breslau, N, Kessler, RC, Chilcoat, HD, Schultz, LR, Davis, GC, Andreski, P (1998). Trauma and posttraumatic stress disorder in the community: the 1996 Detroit area survey of trauma. Archives of General Psychiatry 55, 626632.Google Scholar
Breslau, N, McNally, RJ (2008). The epidemiology of 9–11: technical advances and conceptual conundrums. In 9/11: Mental Health in the Wake of Terrorist Attacks (ed. Neria, Y., Gross, R., Marshall, R. D.), pp. 521528. Cambridge University Press: Cambridge, UK.Google Scholar
Bromet, EJ, Hobbs, MJ, Clouston, SAP, Gonzalez, A, Kotov, R, Luft, BJ (2016). DSM-IV post-traumatic stress disorder among World Trade Center responders 11–13 years after the disaster of 11 September 2001 (9/11). Psychological Medicine 46, 771783.CrossRefGoogle ScholarPubMed
Caramanica, K, Brackbill, RM, Liao, T, Stellman, SD (2014). Comorbidity of 9/11-related PTSD and depression in the World Trade Center health registry 10–11 years postdisaster. Journal of Traumatic Stress 27, 680688.Google Scholar
CATS Consortium (2007). Implementing CBT for traumatized children and adolescents after September 11: lessons learned from the Child and Adolescent Trauma Treatments and Services (CATS) Project. Journal of Clinical Child and Adolescent Psychology: the Official Journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 36, 581592 (http://www.ncbi.nlm.nih.gov/pubmed/18088216).Google Scholar
CATS Consortium (2010). Implementation of CBT for youth affected by the World Trade Center disaster: matching need to treatment intensity and reducing trauma symptoms. Journal of Traumatic Stress 23, 699707 (http://www.mendeley.com/catalog/implementation-cbt-youth-affected-world-trade-center-disaster-matching-need-treatment-intensity-redu/). Accessed 6 January 2016.Google Scholar
Comer, JS, Kendall, PC (2007). Terrorism: the psychological impact on youth. Clinical Psychology: Science and Practice 14, 179212.Google Scholar
Cone, JE, Li, J, Kornblith, E, Gocheva, V, Stellman, SD, Shaikh, A, Schwarzer, R, Bowler, RM, Mph, Ã (2015). Chronic probable PTSD in police responders in the World Trade Center Health Registry ten to eleven years after 9 / 11. American Journal of Industrial Medicine 58, 483493.Google Scholar
Costantino, G, Primavera, LH, Malgady, RG, Costantino, E (2014). Culturally oriented trauma treatments for Latino children post 9/11. Journal of Child and Adolescent Trauma 7, 247255.Google Scholar
Cukor, J, Wyka, K, Mello, B, Olden, M, Jayasinghe, N, Roberts, J (2011). The longitudinal course of PTSD among disaster worker deployed to the World Trade Center following the attacks of September 11th. Journal of Traumatic Stress 24, 506514.Google Scholar
Debchoudhury, I, Welch, AE, Fairclough, MA, Cone, JE, Brackbill, RM, Stellman, SD, Farfel, MR (2011). Comparison of health outcomes among affiliated and lay disaster volunteers enrolled in the World Trade Center Health Registry. Preventive Medicine 53, 359363 (http://dx.doi.org/10.1016/j.ypmed.2011.08.034).Google Scholar
Difede, J, Cukor, J (2009). Evidence-based long-term treatment of mental health consequences of disasters among adults. In Mental Health and Disasters (ed. Neria, Y., Galea, S., Norris, F. H.), pp. 336349. Cambridge University Press: Cambridge (http://ebooks.cambridge.org/ref/id/CBO9780511730030A033). Accessed 23 March 2017.Google Scholar
Difede, J, Cukor, J, Patt, I, Giosan, C, Hoffman, H (2006). The application of virtual reality to the treatment of PTSD following the WTC attack. Annals of the New York Academy of Sciences 1071, 500501 (http://doi.wiley.com/10.1196/annals.1364.052).CrossRefGoogle Scholar
Difede, J, Malta, LS, Best, S, Henn-Haase, C, Metzler, T, Bryant, R, Marmar, C (2007). A randomized controlled clinical treatment trial for World Trade Center attack-related PTSD in disaster workers. The Journal of Nervous and Mental Disease 195, 861865 (http://www.ncbi.nlm.nih.gov/pubmed/18043528).Google Scholar
DiGrande, L, Neria, Y, Brackbill, RM, Pulliam, P, Galea, S (2011). Long-term posttraumatic stress symptoms among 3,271 civilian survivors of the September 11, 2001, terrorist attacks on the World Trade Center. American Journal of Epidemiology 173, 271281 (http://aje.oxfordjournals.org/cgi/doi/10.1093/aje/kwq372).Google Scholar
First, M, Spitzer, R, Gibbon, M, Williams, J (1995). Structured Clinical Interview for DSM-IV, Axis I Disorders, Non-Patient Edition (SCID-N/P, Version 2.0) . New York State Psychiatric Institute, Department of Biometrics Research: New York, NY.Google Scholar
Foa, EB, Cahill, SP, Boscarino, JA, Hobfoll, SE, Lahad, M, Mcnally, RJ, Solomon, Z (2005). Social, psychological, and psychiatric interventions following terrorist attacks: recommendations for practice and research. Neuropsychopharmacology 30, 18061817.Google Scholar
Galea, S, Maxwell, AR (2009). Methodological challenges in studying the mental health consequences of disasters. In Mental Health and Disasters (ed. Neria, Y., Galea, S., Norris, F. H.), pp. 579593. Cambridge University Press: Cambridge (http://ebooks.cambridge.org/ref/id/CBO9780511730030A049). Accessed 13 March 2017.Google Scholar
Galea, S, Nandi, A, Vlahov, D (2005). The epidemiology of post-traumatic stress disorder after disasters. Epidemiologic Reviews 27, 7891 (http://epirev.oxfordjournals.org/content/27/1/78.full). Accessed 16 May 2016.Google Scholar
Galea, S, Vlahov, D, Resnick, H, Ahern, J, Susser, E, Gold, J, Bucuvalas, M, Kilpatrick, D (2003). Trends of probable post-traumatic stress disorder in New York City after the September 11 terrorist attacks. American Journal of Epidemiology 158, 514524.Google Scholar
Garcia-Vera, MP, Sanz, J, Gutierrez, S (2016). A systematic review of the literature on posttraumatic stress disorder in victims of terrorist attacks. Psychological Reports 119, 328359 (http://prx.sagepub.com/lookup/doi/10.1177/0033294116658243). Accessed 22 March 2017.Google Scholar
Haugen, PT, Evces, M, Weiss, DS (2012). Treating posttraumatic stress disorder in first responders: a systematic review. Clinical Psychology Review 32, 370380 (http://dx.doi.org/10.1016/j.cpr.2012.04.001).CrossRefGoogle ScholarPubMed
Kessler, RC, Berglund, P, Demler, O, Jin, R, Merikangas, KR, Walters, EE (2005). Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Archives of General Psychiatry 62, 593602 (http://www.ncbi.nlm.nih.gov/pubmed/15939837). Accessed 10 July 2014.Google Scholar
Kessler, RC, Sonnega, A, Bromet, E, Hughes, M, Nelson, C (1995). Posttraumatic stress disorder in the National Comorbidity Survey. Archives of General Psychiatry 52, 10481060 (http://www.ncbi.nlm.nih.gov/pubmed/7492257). Accessed 20 July 2015.Google Scholar
Kunreuther, H, Michel-Kerjan, E, Porter, B (2003). Assessing, Managing, and Financing Extreme Events: Dealing with Terrorism (http://www.nber.org/papers/w10179). Accessed 16 February 2016.Google Scholar
Levitt, JT, Malta, LS, Martin, A, Davis, L, Cloitre, M (2007). The flexible application of a manualized treatment for PTSD symptoms and functional impairment related to the 9/11 World Trade Center attack. Behaviour Research and Therapy 45, 14191433.Google Scholar
Liu, B, Tarigan, LH, Bromet, EJ, Kim, H (2014). World trade center disaster exposure-related probable posttraumatic stress disorder among responders and civilians: a meta-analysis. PLoS ONE 9, e101491 (http://dx.plos.org/10.1371/journal.pone.0101491).Google Scholar
Lopes, AP, Macedo, TF, Coutinho, ESF, Figueira, I, Ventura, PR (2014). Systematic review of the efficacy of cognitive-behavior therapy related treatments for victims of natural disasters: a worldwide problem L. Chao, ed. PLoS ONE 9, e109013 (http://dx.plos.org/10.1371/journal.pone.0109013). Accessed 23 March 2017.Google Scholar
McCaslin, SE, Inslicht, SS, Henn-Haase, C, Chemtob, C, Metzler, TJ, Neylan, TC, Marmar, CR (2009). Uniformed rescue workers responding to disaster. In Mental Health and Disasters (ed. Neria, Y., Galea, S., Norris, F. H.), pp. 302318. Cambridge University Press: Cambridge (http://ebooks.cambridge.org/ref/id/CBO9780511730030A030). Accessed 22 March 2017.CrossRefGoogle Scholar
Neria, Y, DiGrande, L, Adams, BG (2011). Posttraumatic stress disorder following the September 11, 2001, terrorist attacks: a review of the literature among highly exposed populations. American Psychologist 66, 429446 (http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3386850&tool=pmcentrez&rendertype=abstract).Google Scholar
Neria, Y, Nandi, A, Galea, S (2008). Post-traumatic stress disorder following disasters: a systematic review. Psychological Medicine 38, 467480 (http://www.ncbi.nlm.nih.gov/pubmed/17803838). Accessed 17 May 2016.Google Scholar
Neria, Y, Olfson, M, Gameroff, MJ, DiGrande, L, Wickramaratne, P, Gross, R, Pilowsky, DJ, Neugebaur, R, Manetti-Cusa, J, Lewis-Fernandez, R, Lantigua, R, Shea, S, Weissman, MM (2010). Long-term course of probable PTSD after the 9/11 attacks: a study in urban primary care. Journal of Traumatic Stress 23, 474482.Google Scholar
Norris, FH, Friedman, MJ, Watson, PJ, Byrne, CM, Diaz, E, Kaniasty, K (2002). 60,000 disaster victims speak: part I. An empirical review of the empirical literature, 1981–2001. Psychiatry 65, 207239.Google Scholar
Perrin, MA, Digrande, L, Wheeler, K, Thorpe, L (2007). Differences in PTSD prevalence and associated risk factors among world trade. American Journal of Psychiatry 164, 13851394 (http://www.ncbi.nlm.nih.gov/pubmed/17728424).Google Scholar
Pfeffer, CR, Altemus, M, Heo, M, Jiang, H (2007). Salivary cortisol and psychopathology in children bereaved by the September 11, 2001 terror attacks. Biological Psychiatry 61, 957965.Google Scholar
Pfefferbaum, BJ, Devoe, ER, Stuber, J, Schiff, M, Klein, TP, Fairbrother, G (2004). Psychological impact of terrorism on children and families in the United States. Journal of Aggression, Maltreatment & Trauma 9, 305317 (http://www.tandfonline.com/doi/abs/10.1300/J146v09n03_01).Google Scholar
Pfefferbaum, BJ, Weems, CF, Scott, BG, Nitiéma, P, Noffsinger, MA, Pfefferbaum, RL, Varma, V, Chakraburtty, A (2013). Research methods in child disaster studies: a review of studies generated by the September 11, 2001, terrorist attacks; the 2004 Indian Ocean Tsunami; and Hurricane Katrina. Child & Youth Care Forum 42, 285337 (http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3892998&tool=pmcentrez&rendertype=abstract).Google Scholar
Pietrzak, RH , Feder, A, Singh, R, Schechter, CB, Bromet, EJ, Katz, CL, Reissman, DB, Ozbay, F, Sharma, V, Crane, M, Harrison, D, Herbert, R, Levin, SM, Luft, BJ, Moline, JM, Stellman, JM, Udasin, IG, Landrigan, PJ, Southwick, SM (2014). Trajectories of PTSD risk and resilience in World Trade Center responders: an 8-year prospective cohort study. Psychological Medicine 44, 205219 (http://journals.cambridge.org/action/displayFulltext?type=6&fid=9111650&jid=PSM&volumeId=44&issueId=01&aid=9111649&bodyId=&membershipNumber=&societyETOCSession=&fulltextType=RA&fileId=S0033291713000597).Google Scholar
Schneier, FR, Neria, Y, Pavlicova, M, Hembree, E, Suh, EJ, Amsel, L, Marshall, RD (2012). Combined prolonged exposure therapy and paroxetine for PTSD related to the World Trade Center attack: a randomized controlled trial. American Journal of Psychiatry 169, 8089.Google Scholar
Silver, RC, Holman, EA, McIntosh, DN, Poulin, M, Gil-Rivas, V, Pizarro, J (2005 a). Coping with a national trauma: a nationwide longitudinal study of responses to the terrorist attacks of September 11th. In 9/11: Mental Health in the Wake of Terrorist Attacks, pp. 4570. Trauma of Terrorism: Sharing Knowledge and Shared Care, An International Handbook (ed. Danieli, Y., Brom, D., Sills, J.). The Haworth Maltreatment & Trauma Press, an imprint of The Haworth Press, Inc., 2005Google Scholar
Silver, SM, Rogers, S, Knipe, J, Colelli, G (2005 b). EMDR therapy following the 9/11 terrorist attacks: a community-based intervention project in New York City. International Journal of Stress Management 12, 2942.Google Scholar
Susser, E, Schwartz, S, Morabia, A, Bromet, EJ (2006). Psychiatric Epidemiology, 1st edn. Oxford University Press: New York.Google Scholar
Tapp, LC, Baron, S, Bernard, B, Driscoll, R, Mueller, C, Wallingford, K (2005). Physical and mental health symptoms among NYC transit workers seven and one-half months after the WTC attacks. American Journal of Industrial Medicine 47, 475483.Google Scholar
Wilson, LC (2015). A systematic review of probable posttraumatic stress disorder in first responders following man-made mass violence. Psychiatry Research 229, 2126 (http://linkinghub.elsevier.com/retrieve/pii/S0165178115003637).Google Scholar
Zvolensky, MJ, Kotov, R, Schechter, CB, Gonzalez, A, Vujanovic, A, Pietrzak, RH, Crane, M, Kaplan, J, Moline, J, Southwick, SM, Feder, A, Udasin, I, Reissman, DB, Luft, BJ (2015). Post-disaster stressful life events and WTC-related posttraumatic stress, depressive symptoms, and overall functioning among responders to the World Trade Center disaster. Journal of Psychiatric Research 61, 97105 (http://www.sciencedirect.com/science/article/pii/S0022395614003203).Google Scholar