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Selective serotonin re-uptake inhibitors: use in depression

Published online by Cambridge University Press:  02 January 2018

I. N. Ferrier ,
T. Silverstone  and
D. Eccleston
I. N. Ferrier
Affiliation:
Department of Psychiatry, School of Neuroscience, University of Newcastle upon Tyne NE1 4LP
T. Silverstone
Affiliation:
Department of Psychological Medicine, St Bartholomew's Hospital, London EC1A 7BE
D. Eccleston
Affiliation:
Department of Psychiatry, School of Neuroscience, University of Newcastle upon Tyne NE1 4LP
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This short review outlines the clinical profile of the selective serotonin re-uptake inhibitors (SSRIs). There has been much recent publicity and promotion of this group of drugs and this review attempts to give a balanced account of their current place in the treatment of depression. Although a large number of preclinical and clinical trials have been carried out many questions and problems remain – it is important to proceed carefully and carry out (and replicate) controlled independent clinical trials. The views of general psychiatrists and GPs about these drugs in normal clinical practice will be the acid test – this will be particularly important in view of their cost.

Type
Keynotes
Information
Psychiatric Bulletin , Volume 16 , Issue 12 , December 1992 , pp. 737 - 739
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
Copyright © Royal College of Psychiatrists 1992

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