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New processing technologies: an overview

Published online by Cambridge University Press:  28 February 2007

Grahame W. Gould
Grahame W. Gould*
Affiliation:
17 Dove Road, Bedford MK41 7AA, UK
*
Corresponding Author: Professor G. W. Gould, fax +44 1234 222277, email [email protected]
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Abstract

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Most food-preservation techniques act by slowing down or completely inhibiting the growth of micro-organisms. Few techniques act by inactivating them. While heat remains the technique most extensively used for inactivation, there has been increasing interest recently in the development of alternative approaches in response to the desires of consumers for products which are less organoleptically and nutritionally damaged during processing and less reliant on additives than previously. The new approaches, therefore, mostly involve technologies that offer full or partial alternatives to heat for the inactivation of bacteria, yeasts and moulds. They include the application to foods of high hydrostatic pressure, high-voltage electric discharges, high-intensity laser and non-coherent light pulses, ‘manothermosonication’ (the combination of mild heating with ultrasonication and slightly-raised pressure), and high-magnetic-field pulses. In addition, a number of naturally-occurring antimicrobials, including lysozyme and low-molecular-weight products of micro-organisms are finding increasing use. High pressure is being used commercially to non-thermally pasteurize a number of foods, while the other physical procedures are in various stages of development and commercial evaluation. Possible nutritional consequences have so far been given little attention compared with microbiological ones.

Keywords

Food preservationFood processingFood safetyNew food-processing technologies
Type
Symposium on ‘Nutritional effects of new processing technologies’
Information
Proceedings of the Nutrition Society , Volume 60 , Issue 4 , November 2001 , pp. 463 - 474
Copyright
Copyright © The Nutrition Society 2001

References

Ahmed, FIK & Russell, C (1975) Synergism between ultrasonic waves and hydrogen peroxide in the killing of microorganisms. Journal of Applied Bacteriology 39, 31–40.CrossRefGoogle ScholarPubMed
Alliger, H (1975) Ultrasonic disruption. American Laboratory 10, 75–85.Google Scholar
Al-Zoreky, N, Ayres, JW & Sandine, WE (1991) Antimicrobial action of Microgard TM against food spoilage and pathogenic microorganisms. Journal of Dairy Science 74, 748–763.CrossRefGoogle Scholar
Banks, JG, Board, RG & Sparks, NHC (1986) Natural antimicrobial systems and their potential in food preservation of the future. Biotechnology and Applied Biochemistry 8, 103–147.Google ScholarPubMed
Barbosa-Canovas, GV, Pothakamury, UR & Swanson, BG (1995) State of the art technologies for the sterilization of foods by non-thermal processes: physical methods. In Food Preservation by Moisture Control: Fundamentals and Applications, pp. 493–532 [Barbosa-Canovas, GV and Welti-Chanes, J, editors]. Lancaster, PA: Technomic Publishing Co.Google Scholar
Basset, J & Machebouf, MA (1932) Etude sur les effets biologiques des ultrapressions: résistance de bactéries, des diastases et de toxines aux pressions très élevées (Study of the biological effects of ultrapressure: resistance of bacteria, the diastases and toxins to very high pressures). Comptes Rendus Hebdomaire Science Academie des Sciences Paris 196, 1431–1442.Google Scholar
Beuchat, LR (1994) Antimicrobial properties of spices and their essential oils. In Natural Antimicrobial Systems and Food Preservation, pp. 167–180 [Dillon, VM and Board, RG, editors]. Wallingford, Oxon.: CAB International.Google Scholar
Bjorck, L, Claesson, Q & Schultness, W (1979) The lactoperoxidase/ thiocyanate/hydrogen peroxide system as a temporary preservative for raw milk in developing countries. Milchwissenschaft 34, 726–729.Google Scholar
Board, RG (1995) Natural antimicrobials from animals. In New Methods of Food Preservation, pp. 40–57 [Gould, GW, editor]. Glasgow: Blackie Academic and Professional.CrossRefGoogle Scholar
Boulart, J (1983) Process for protecting a fluid and installations for realization of that process. French Patent no. 2 513 087.Google Scholar
Burgos, J, Ordonez, JA & Sala, FJ (1972) Effect of ultrasonic waves on the heat resistance of Bacillus cereus and Bacillus coagulans spores. Applied Microbiology 24, 497–498.CrossRefGoogle Scholar
Bushnell, AH, Dunn, JE, Clark, RW & Pearlman, JS (1993) High pulsed voltage system for extending the shelf life of pumpable food products. US Patent no. 5 235 905.Google Scholar
Butz, P & Ludwig, H (1986) Pressure inactivation of microorganisms at moderate temperatures. Physica 139–140B, 875–877.Google Scholar
Carini, S & Lodi, R (1982) Inhibition of germination of clostridial spores by lysozyme. Industrie Latte 18, 35–48.Google Scholar
Carlez, A, Cheftel, J-C, Rosec, JP, Richard, N, Saldana, J-L, & Balny, C (1992) Effects of high pressure and bacteriostatic agents on the destruction of Citrobacter freundii in minced beef muscle. In High Pressure and Biotechnology. Colloque INSERM/J, pp. 365–368 [Balny, C, Hayashi, R, Heremans, K and Masson, P, editors]. Montrouge: Libby Eurotech Ltd.Google Scholar
Carminati, D, Nevianti, E & Muchetti, G (1985) Activity of lysozyme on vegetative cells of Clostridium tyrobutyricum. Latte 10, 194–198.Google Scholar
Castro, AI, Barbosa-Canovas, GV & Swanson, BG (1993) Microbial inactivation in foods by pulsed electric fields. Journal of Food Processing and Preservation 17, 47–73.CrossRefGoogle Scholar
Chatzlopou, A, Miles, RJ & Anagnostopoulos, G (1993) Destruction of Gram-negative bacteria. International Patent Application no. WO 93/00822.Google Scholar
Chernomodik, LV, Sukharev, SI, Popov, SV, Patushenko, VF, Sorkirko, AV, Abidor, IG & Chizmadzhev, YA (1987) The electrical breakdown of cell and lipid membranes: the similarity of phenomenologies. Biochimica et Biophysica Acta 972, 360–365.CrossRefGoogle Scholar
Clouston, JG & Wills, PA (1969) Initiation of germination and inactivation of Bacillus pumilus spores by hydrostatic pressure. Journal of Bacteriology 97, 684–690.CrossRefGoogle ScholarPubMed
Clouston, JG & Wills, PA (1970) Kinetics of germination and inactivation of Bacillus pumilus spores by hydrostatic pressure. Journal of Bacteriology 103, 140–143.CrossRefGoogle ScholarPubMed
Cobb, CM, McCawley, TK & Killoy, WJ (1992) A preliminary study on the effects of the Nd:YAG laser on root surfaces and subgingival microflora in vivo. Journal of Periodontology 63, 701–707.CrossRefGoogle Scholar
Costa, JL & Hofmann, GA (1987) Malignancy treatment. US Patent no. 4 665 898.Google Scholar
Deans, SG & Ritchie, G (1987) Antibacterial properties of plant essential oils. International Journal of Food Microbiology 5, 165–180.CrossRefGoogle Scholar
Delves-Broughton, J (1990) Nisin and its uses. Food Technology 44, 100–117.Google Scholar
Delves-Broughton, J & Gasson, MJ (1994) Nisin. In Natural Antimicrobial Systems and Food Preservation, pp. 99–132 [Dillon, VM and Board, RG, editors]. Wallingford, Oxon.: CAB International.Google Scholar
Dodd, HM, Horn, N, Hao, Z & Gasson, MJ (1992) A lactococcal expression system for engineered nisins. Applied and Environmental Microbiology 58, 3683–3693.CrossRefGoogle ScholarPubMed
Doevenspeck, H (1960) Method for food preservation. German Patent no. 1 237 541.Google Scholar
Dring, JG (1976) Some aspects of the effects of hydrostatic pressure on microorganisms. In Inhibition and Inactivation of Microorganisms, pp. 257–277 [Skinner, FA and Hugo, WB, editors]. London: Academic Press.Google Scholar
Dunn, JE, Clark, RW, Asmus, JF, Pearlman, JS, Boyer, K & Parrichaud, F (1988) Method and apparatus for preservation of foodstuffs. International Patent no. WO88/03369.Google Scholar
Dunn, JE & Pearlman, JS (1987) Methods and apparatus for extending the shelf life of fluid food products. US Patent no. 4 695 472.Google Scholar
Earnshaw, RG (1995) High pressure microbial inactivation kinetics. In High Pressure Processing of Foods, pp. 37–46 [Ledward, DA, Johnston, DE, Earnshaw, RG and Hasting, APM, editors]. Nottingham: Nottingham University Press.Google Scholar
EEC (1989). Comprehensive EEC Directive on Food Additives. Document III-3761-Rev. 2. Luxembourg: European Communities.Google Scholar
Ekstrand, B (1994) Lactoperoxidase and lactoferrin. In Natural Antimicrobial Systems and Food Preservation, pp. 15–64 [Dillon, VM and Board, RG, editors]. Wallingford, Oxon.: CAB International.Google Scholar
Eyles, MJ & Richardson, KC (1988) Thermophilic bacteria and food spoilage. CSIRO Food Research Quarterly 48, 19–24.Google Scholar
Eze, MO (1990) Consequences of the lipid bilayer to membrane-associated reactions. Journal of Chemical Education 67, 17–20.CrossRefGoogle Scholar
Farbood, MI, Macneil, JH & Ostovar, K (1976) Effect of rosemary spice extract on growth of microorganisms in meats. Journal of Milk and Food Technology 39, 675–679.CrossRefGoogle Scholar
Farr, D (1990) High pressure technology in the food industry. Trends in Food Science and Technology 1, 14–16.CrossRefGoogle Scholar
Fowler, GG & Gasson, MJ (1991) Antibiotics – nisin. In Food Preservatives, pp. 135–152 [Russell, NJ and Gould, GW, editors]. Glasgow: Blackie Academic and Professional.Google Scholar
Fryer, P (1995) Electrical resistance heating of foods. In New Methods of Food Preservation, pp. 205–235 [Gould, GW, editor]. Glasgow: Blackie Academic & Professional.CrossRefGoogle Scholar
Garcia, ML, Burgos, J, Sanz, B & Ordonez, JA (1989) Effect of heat and ultrasonic waves on the survival of two strains of Bacillus subtilis. Journal of Applied Bacteriology 67, 619–628.Google ScholarPubMed
Glaser, RW, Leikin, SL, Chernomordik, LV, Pastushenko, VF & Sokirko, AV (1988) Reversible electrical breakdown of lipid bilayers: formation and evolution of pores. Biochimica et Biophysica Acta 940, 275–281.CrossRefGoogle ScholarPubMed
Gould, GW & Hitchins, AD (1963) Sensitization of spores to lysozyme and hydrogen peroxide with agents which rupture disulphide bonds. Journal of General Microbiology 33, 413–422.CrossRefGoogle ScholarPubMed
Gould, GW & Sale, AJH (1970) Initiation of germination of bacterial spores by hydrostatic pressure. Journal of General Microbiology 60, 335–346.CrossRefGoogle ScholarPubMed
Grahl, T, Sitzmann, W & Mak, H (1992) Killing of microorganisms in fluid media by high voltage pulses. DECHEMA Biotechnology Conference Series 5B, 675–678.Google Scholar
Grant, S, Patterson, M & Ledward, D (2000) Food processing gets freshly squeezed. Chemistry and Industry 24 January issue, 55–58.Google Scholar
Hamilton, WA & Sale, AJH (1967) Effects of high electric fields on microorganisms 11. Mechanism of action of the lethal effect. Biochimica et Biophysica Acta 148, 789–795.CrossRefGoogle Scholar
Harnulv, BG & Kandusamy, C (1982) Increasing the keeping quality of raw milk by activation of the lactoperoxidase system. Results for Sri Lanka. Milchwissenschaft 37, 454–457.Google Scholar
Harvey, E & Loomis, A (1929) The destruction of luminous bacteria by high frequency sound waves. Journal of Bacteriology 17, 373–379.CrossRefGoogle ScholarPubMed
Hayakawa, I, Kanno, T, Tomita, M & Figio, Y (1994) Application of high pressure for spore inactivation and protein denaturation. Journal of Food Science 59, 159–163.CrossRefGoogle Scholar
Heremans, K (1995) High pressure effects on biomolecules. In High Pressure Processing of Foods, pp. 81–97 [Ledward, DA, Johnston, DE, Earnshaw, RG and Hasting, APM, editors]. Nottingham: Nottingham University Press.Google Scholar
Hill, C (1995) Bacteriocins: natural antimicrobials from microorganisms. In New Methods of Food Preservation, pp. 22–39 [Gould, GW, editor]. Glasgow: Blackie Academic and Professional.CrossRefGoogle Scholar
Hite, BH (1899) The effect of pressure in the preservation of milk. Bulletin of the West Virginia Experiment Station no. 58, pp. 15–35.Morgantown, VA: University of West Virginia.Google Scholar
Hite, BH, Giddings, NJ & Weakley, CW (1914) The effect of pressure on certain microorganisms encountered in the preservation of fruits and vegetables. Bulletin of the West Virginia Experiment Station no. 146, pp. 3–67.Morgantown, VA: University of West Virginia.Google Scholar
Hoffman, GA (1985) Inactivation of microorganisms by an oscillating magnetic field. US Patent no. 4 524 079 and International Patent no. WO85/02094.Google Scholar
Hoffman, GA & Evans, EG (1986) Electronic, genetic, physical and biological aspects of electromanipulation. IEEE Medical Biology Magazine 5, 6–25.CrossRefGoogle Scholar
Hoover, DG (1993) Pressure effects on biological systems. Food Technology 47, 150–155.Google Scholar
Hoover, DG, Metrick, K, Papineau, AM, Farkas, DF & Knorr, D (1989) Biological effects of high hydrostatic pressure on food microorganisms. Food Technology 43, 99–107.Google Scholar
Horie, Y, Kimura, K, Ida, M,. Yosida, Y & Ohki, K (1991) Jam preservation by pressure pasteurization. Nippon Nogeiku Kaichi 65, 975–980.CrossRefGoogle Scholar
Hulsheger, H & Niemann, EG (1980) Lethal effect of high voltage pulses on E. coli K12, Radiation and Environmental Biophysics 18, 281–288.CrossRefGoogle ScholarPubMed
Hulsheger, H, Potel, J & Neimann, EG (1981) Killing of bacteria with electric pulses of high field strength. Radiation and Environmental Biophysics 20, 53–61.CrossRefGoogle ScholarPubMed
Hulsheger, H, Potel, J & Neimann, EG (1983) Electric field effects on bacteria and yeast cells. Radiation and Environmental Biophysics 22, 149–156.CrossRefGoogle ScholarPubMed
Isaacs, NS, Chilton, P & Mackey, B (1995) Studies on the inactivation by high pressure of microorganisms. In High Pressure Processing of Foods, pp. 65–79 [Ledward, DA, Johnston, DE, Earnshaw, RG and APM, Hasting, editors]. Nottingham: Nottingham University Press.Google Scholar
Jayaram, S, Castle, GSP & Margaritis, A (1992) Kinetics of sterilization of Lactobacillus brevis by the application of high voltage pulses. Biotechnology and Bioengineering 40, 1412–1420.CrossRefGoogle ScholarPubMed
Johnson, EA (1989) The potential application of antimicrobial proteins in food preservation. Journal of Dairy Science 72, 123–124.Google Scholar
Kabara, J (1991) Phenols and chelators. In Food Preservatives, pp. 200–214 [Russell, NJ and Gould, GW, editors]. Glasgow: Blackie Academic and Professional.Google Scholar
Kalchayanand, N, Sikes, T, Dunne, CP & Ray, B (1994) Hydrostatic pressure and electroporation have increased bactericidal efficiency in combination with bacteriocins. Applied and Environmental Microbiology 60, 4174–4177.CrossRefGoogle ScholarPubMed
Kimugasa, H, Takao, T, Fukumoto, K & Ishihara, M (1992) Changes in tea components during processing and preservation of tea extracts by hydrostatic pressure sterilization. Nippon Nogeiku Kaichi 66, 707–712.CrossRefGoogle Scholar
Kliss, WS (1960) Effectiveness of pimaricin as an alternative to sorbate for the inhibition of yeasts and moulds in foods. Food Technology 13, 124–132.Google Scholar
Knorr, D (1995) Hydrostatic pressure treatment of food: microbiology. In New Methods of Food Preservation, pp. 159–175 [Gould, GW, editor]. Glasgow: Blackie Academic and Professional.CrossRefGoogle Scholar
Kobayashi, S, Tomita, M, Kawase, K, Takase, M, Miyakawa, H, Yamauchi, K, Saito, H, Abe, H & Shimamura, S (1990) Lactoferrin hydrolysate for use as an antibacterial agent and as a tyrosinase inhibition agent. European Patent Application no. 90125035.7.Google Scholar
Kowalski, E, Ludwig, H & Tausche, B (1992) Hydrostatic pressure to sterilize foods 1. Application to pepper (Piper nigrum L). Deutsche Lebensmittel Rundschau 88, 74–75.Google Scholar
Kuipers, OP, Rollema, HS, Yap, WMG, Boot, HJ, Siezen, RJ & De Vos, WM (1992) Engineering dehydrated amino acid residues in the antimicrobial peptide nisin. Journal of Biological Chemistry 267, 2430–2434.CrossRefGoogle ScholarPubMed
Larson, WP, Hartzel, TB & Diehl, HS (1918) The effect of high pressure on bacteria. Journal of Infectious Diseases 22, 271–279.CrossRefGoogle Scholar
Lattanzio, V, de Cicco, V, Di Venere, D, Lima, G & Salermo, M (1994) Antifungal activity of phenolics against fungi commonly encountered during storage. Italian Journal of Food Science 6, 23–30.Google Scholar
Leistner, L (1995) Principles and applications of hurdle technology. In New Methods of Food Preservation, pp. 1–21 [Gould, GW, editor]. Glasgow: Blackie Academic and Professional.Google Scholar
Lopez, P, Sala, FJ, Fuente, JL, Condon, S, Raso, J & Burgos, J (1994) Inactivation of peroxidase, lipoxygenase and polyphenoloxidase by manothermosonication. Journal of Agricultural and Food Chemistry 42, 552–556.CrossRefGoogle Scholar
Ludwig, H, Bieler, C, Hallbauer, K & Scigalla, W (1992) Inactivation of microorganisms by hydrostatic pressure. In High Pressure Biotechnology. Colloque INSERM/J, pp. 25–32 [Balny, C, Hayashi, R, Heremans, K and Masson, P, editors]. Montrouge: Libby Eurotext Ltd.Google Scholar
Mertens, B (1995) Hydrostatic pressure treatment of food: equipment and processing. In New Methods of Food Preservation, pp. 135–158 [Gould, GW, editor]. Glasgow: Blackie Academic and Professional.CrossRefGoogle Scholar
Mertens, B & Knorr, D (1992) Development of nonthermal processes for food preservation. Food Technology 46, 124–133.Google Scholar
Metrick, C, Hoover, DG & Farkas, DF (1989) Effects of high hydrostatic pressure on heat-sensitive strains of Salmonella. Journal of Food Science 54, 1547–1564.CrossRefGoogle Scholar
Mizuno, A & Hori, Y (1988) Destruction of living cells by pulsed high voltage applications. IEEE Transactions on Industrial Applications 24, 387–395.CrossRefGoogle Scholar
Monticello, DJ (1989) Control of microbial growth with nisin/ lysozyme formulations. European Patent Application no. 89123445.2.Google Scholar
Moreau, C (1995) Semicontinuous high pressure cell for liquid processing. In High Pressure Processing of Foods, pp. 181–197 [Ledward, DA, Johnston, DE, Earnshaw, RG and Hasting, APM, editors]. Nottingham: Nottingham University Press.Google Scholar
Mullin, J (1995) Microwave processing. In New Methods of Food Preservation, pp. 112–134 [Gould, GW, editor]. Glasgow: Blackie Academic and Professional.CrossRefGoogle Scholar
Murrell, WG & Wills, PA (1977) Initiation of Bacillus spore germination by hydrostatic pressure: effect of temperature. Journal of Bacteriology 129, 1272–1280.CrossRefGoogle ScholarPubMed
Nakamura, R, Kato, A & Kobayashi, K (1990) Novel bifunctional lysozyme-dextran conjugate that acts on both Gram-negative and Gram-positive bacteria. Agricultural and Biological Chemisry 54, 3057–3059.Google Scholar
Neumann, E, Sowers, AE & Jordan, CA (editors) (1989). Electroporation and Electrofusion in Cell Biology. New York: Plenum Press.CrossRefGoogle Scholar
Nychas, GJE (1995) Natural antimicrobials from plants. In New Methods of Food Preservation, pp. 58–89 [Gould, GW, editor]. Glasgow: Blackie Academic and Professional.CrossRefGoogle Scholar
Ordonez, JA, Aguilera, MA, Garcia, ML & Sanz, B (1987) Effects of combined ultrasonic and heat treatment (thermosonication) on the survival of a strain of Staphylococcus aureus. Journal of Dairy Research 54, 61–67.CrossRefGoogle Scholar
Ordonez, JA, Sanz, B, Hernandez, PE & Lopez-Lorenzo, P (1984) A note on the effect of combined ultrasonic and heat treatments on the survival of thermoduric streptococci. Journal of Applied Bacteriology 56, 175–177.CrossRefGoogle ScholarPubMed
Oxen, P & Knorr, D (1993) Baroprotective effects of high solute concentrations against inactivation of Rhodotorula rubra. Lebensmittel Wissenschaft Technologie 26, 220–223.CrossRefGoogle Scholar
Palaniappan, S (1996) High isostatic pressure processing of foods. In New Processing Technologies Yearbook, pp. 51–66 [Chandarana, PI, editor]. Washington, DC: National Food Processors Association.Google Scholar
Patterson, MF & Loaharanu, P (2000) Irradiation. In The Microbiological Safety and Quality of Food, pp. 65–100 [Lund, BM, Baird-Parker, AC and Gould, GW, editors]. Gaithersburg, MD: Aspen Publishers Inc.Google Scholar
Patterson, MF, Quinn, M, Simpson, R & Gilmour, A (1995 a) Effects of high pressure on vegetative pathogens. In High Pressure Processing of Foods, pp. 47–63 [Ledward, DA, Johnston, DE, Earnshaw, RG and Hasting, APM, editors]. Nottingham: Nottingham University Press.Google ScholarPubMed
Patterson, MF, Quinn, M, Simpson, R & Gilmour, A (1995 b) Sensitivity of vegetative pathogens to high hydrostatic pressure treatment in phosphate-buffered saline and foods. Journal of Food Protection 58, 524–529.CrossRefGoogle ScholarPubMed
Pothakamury, UR, Monsalve-Gonzalea, A, Barbosa-Canovas, GV & Swanson, BG (1993) Magnetic-field inactivation of microorganisms and generation of biological changes. Food Technology 47, 85–92.Google Scholar
Powell, GL & Wisenart, B (1991) Comparison of three lasers for dental instrument sterilization. Lasers in Surgery and Medicine 11, 69–71.CrossRefGoogle ScholarPubMed
Pruitt, KM & Reiter, B (1985) Biochemistry of the peroxidase system: antimicrobial effects. In The Lactoperoxidase System, pp. 143–442 [Pruitt, K and Tenovuo, JO, editors]. New York: Marcel Dekker.Google Scholar
Qin, B, Zhang, Q, Barbosa-Canovas, GV, Swanson, BG & Pedrow, PD (1994) Inactivation of microorganisms by pulsed electric fields with different voltage wave forms. IEEE Transactions on Electrical Insulation 1, 1047–1057.Google Scholar
Qin, B, Zhang, Q, Barbosa-Canovas, GV, Swanson, BG & Pedrow, PD (1995) Pulsed electric field chamber design using field element method. Transactions of the American Society of Agricultural Engineers 38, 557–565.CrossRefGoogle Scholar
Ray, B & Daeschel, MA (1994) Bacteriocins of starter cultures. In Natural Antimicrobial Systems and Food Preservation, pp. 133–166 [Dillon, VM and Board, RG, editors]. Wallingford, Oxon: CAB International.Google Scholar
Ray, B, Johnson, C & Wanismail, B (1984) Factors influencing lysis of frozen. Escherichia coli cells by lysozyme. Cryo Letters 5, 183–190.Google Scholar
Reiter, B, Fulford, RJ, Marshall, VM, Yarrow, N, Ducker, MJ & Knutsson, M (1981) An evaluation of the growth promoting effect of the lactoperoxidase system in newborn calves. Animal Production 32, 297–306.Google Scholar
Reiter, B & Harnulv, G (1984) Lactoperoxidase natural antimicrobial system: natural occurrence, biological functions and practical applications. Journal of Food Protection 47, 724–732.CrossRefGoogle Scholar
Roberts, CM & Hoover, DG (1996) Sensitivity of Bacillus coagulans spores to combinations of high hydrostatic pressure, heat, acidity and nisin. Journal of Applied Bacteriology 81, 363–368.CrossRefGoogle Scholar
Rooney, J, Midda, M & Leeming, J (1994) A laboratory investigation of the bactericidal effect of a Nd:Yag laser. British Dental Journal 176, 61–64.CrossRefGoogle Scholar
Saito, H, Miyakawa, H, Tamura, Y, Shinamura, Y & Tomita, M (1991) Potent bactericidal activity of bovine lactoferrin hydrolysate produced by heat treatment at acidic pH. Journal of Dairy Science 74, 3724–3730.CrossRefGoogle ScholarPubMed
Sala, FJ, Burgos, J, Condon, S, Lopez, P & Raso, J (1995) Effect of heat and ultrasound on microorganisms and enzymes. In New Methods of Food Preservation, pp. 176–204 [Gould, GW, editor]. Glasgow: Blackie Academic and Professional.CrossRefGoogle Scholar
Sale, AJH, Gould, GW & Hamilton, WA (1970) Inactivation of bacterial spores by hydrostatic pressure. Journal of General Microbiology 60, 323–334.CrossRefGoogle ScholarPubMed
Sale, AJH & Hamilton, WA (1967) Effects of high electric fields on microorganisms I: killing of bacteria and yeasts. Biochimica et Biophysica Acta 148, 781–788.CrossRefGoogle Scholar
Sale, AJH & Hamilton, WA (1968) Effects of high electric fields on microorganisms II: lysis of erythrocytes and protoplasts. Biochimica et Biophysica Acta 163, 37–45.CrossRefGoogle Scholar
Samuelson, KJ, Rupnow, JH & Froning, GW (1985) The effect of lysozyme and ethylenediaminetetraacetic acid on Salmonella on broiler parts. Poultry Science 64, 1488–1490.CrossRefGoogle ScholarPubMed
Sanz, B, Palacios, P, Lopez, P & Ordonez, JA (1985) Effect of ultrasonic waves on the heat resistance of Bacillus stearothermophilus spores. In Fundamental and Applied Aspects of Bacterial Spores, pp. 215–259 [Dring, GJ, Ellar, DJ and Gould, GW, editors]. London: Academic Press.Google Scholar
Sato, M & Kawata, H (1991) Pasteurization method for liquid foodstuffs. Japanese Patent no. 398 565.Google Scholar
Scherba, G, Weizel, RM & O'Brien, JR (1991) Quantitative assessment of the germicidal efficacy of ultrasonic energy. Applied and Environmental Microbiology 57, 2079–2084.CrossRefGoogle ScholarPubMed
Scott, D, Hammer, FE & Szalkucki, TJ (1987) Bioconversions: enzyme technology. In Food Biotechnology, pp. 413–442 [Knorr, D, editor]. New York: Marcel Dekker.Google Scholar
Selman, J (1992) New technologies for the food industry. Food Science and Technology Today 6, 205–209.Google Scholar
Seyerderholm, I & Knorr, D (1992) Reduction of Bacillus stearothermophilus spores by combined high pressure and temperature treatments. Journal of Food Industry 43, 17–20.Google Scholar
Shelef, LA (1983) Antimicrobial effects of spices. Journal of Food Safety 6, 29–44.CrossRefGoogle Scholar
Shigahisa, T, Ohmori, T, Saito, A, Tuj, S & Hayashi, R (1991) Effects of high pressure on the characteristics of pork slurries and inactivation of microorganisms associated with meat and meat products. International Journal of Food Microbiology 12, 207–216.CrossRefGoogle Scholar
Sitzmann, W (1995) High voltage pulse techniques for food preservation. In New Methods of Food Preservation, pp. 236–252 [Gould, GW, editor]. Glasgow: Blackie Academic and Professional.CrossRefGoogle Scholar
Sommers, EB & Taylor, SL (1987) Antibotulinal effectiveness of nisin in pasteurized processed cheese spreads. Journal of Food Protection 50, 842–848.CrossRefGoogle Scholar
Styles, MF, Hoover, DG & Farkas, DF (1991) Response of Listeria monocytogenes and Vibrio parahaemolyticus to high hydrostatic pressure. Journal of Food Science 56, 1404–1407.CrossRefGoogle Scholar
Takahashi, K, Ishi, H & Ishikawa, H (1991) Sterilization of microorganisms by hydrostatic pressure at low temperature. In High Pressure Science of Food, pp. 225–232 [Hayashi, R, editor]. Kyoto: San-Ei Publishing Co.Google Scholar
Thomas, EL, Pera, KA, Smith, KW & Chwang, AK (1983) Inhibition of Streptococcus mutans by the lactoperoxidase antimicrobial system. Infection and Immunity 39, 767–778.CrossRefGoogle ScholarPubMed
Timson, WJ & Short, AJ (1965) Resistance of microorganisms to hydrostatic pressure. Biotechnology and Bioengineering 7, 139–159.CrossRefGoogle Scholar
Tomita, M, Bellamy, W, Takase, M, Yamauchi, K, Wakabayashi, H & Kawase, K (1991) Potent antibacterial peptides generated by pepsin digestion of bovine lactoferrin. Journal of Dairy Science 74, 4137–4142.CrossRefGoogle ScholarPubMed
Tranter, HS (1994) Lysozyme, ovotransferrin and avidin. In Natural Antimicrobial Systems and Food Preservation, pp. 65–98 [Dillon, VM and Board, RG, editors]. Wallingford, Oxon.: CAB International.Google Scholar
Tranter, HS & Board, RG (1982) Review: the antimicrobial defense of avian eggs: biological perspective and chemical basis. Journal of Applied Biochemistry 4, 295–338.Google Scholar
Tsong, TY (1991) Minireview: electroporation of cell membranes. Biophysical Journal 60, 297–316.CrossRefGoogle Scholar
Wasserfall, F, Voss, E & Prokopek, D (1976) Experiments on cheese ripening: the use of lysozyme instead of nitrite to inhibit late blowing of cheese. Kiel Milchwirtschaft Forschungsberung 28, 3–16.Google Scholar
Wilkins, KM & Board, RG (1989) Natural antimicrobial systems. In Mechanisms of Action of Food Preservation Procedures, pp. 285–362 [Gould, GW, editor]. London: Elsevier Applied Science.Google Scholar
Wills, PA (1974) Effects of hydrostatic pressure and ionizing radiation on bacterial spores. Atomic Energy Australia 17, 2–10.Google Scholar
World Health Organization (1999). High-dose Irradiation: Wholesomeness of Food Irradiated with Doses Above 10 kGy. WHO Technical Report Series no. 890. Geneva: WHO.Google Scholar
Zhang, Q, Barbosa-Canovas, GV & Swanson, BG (1994) Engineering aspects of pulsed electric field pasteurization. Journal of Food Engineering 25, 261–268.CrossRefGoogle Scholar
Zhang, Q, Qin, BL, Barbosa-Canovas, GV & Swanson, BG (1995) Inactivation of E. coli for food pasteurization by high strength pulsed electric fields. Journal of Food Processing and Preservation 19, 103–118.CrossRefGoogle Scholar