ALMA, the Atacama Large Millimeter/submillimeter Array, provides a large collecting area at a location on a high dry site, endowing it with unparalleled potential for sensitive spectral line observations. Its wide frequency coverage, superb receivers and flexible backend will ensure that that potential is met. Although in the Southern Hemisphere, its tropical latitude ensures good coverage of the northern sky. Since the last meeting on astrophysical masers, the ALMA team has substantially enhanced its capability for line observations. Japan's entry into ALMA has provided increased sensitivity with the addition of the 16 antennas of the Atacama Compact Array, equivalent to eight additional 12m telescopes. The first four cartridges for the baseline ALMA receiver packages (to be augmented by three other bands owing to Japanese participation) have been accepted, with performance above the already-challenging specifications. At first light, ALMA will offer nearly complete frequency coverage of the millimeter and submillimeter spectral windows, ensuring coverage of a variety of masering transitions. ALMA's flexibility as a spectrometer has increased with the enhancement of the baseline correlator with tunable filter banks, and with the addition of a separate correlator for the ACA. As an example of the increased flexibility, ALMA is now capable of multi-spectral-region and multi-resolution modes. With the former, one might observe e.g. four separate transitions anywhere within one of four 2 GHz bands with a high resolution bandwidth. With the latter, one might simultaneously observe with low spectral resolution over a wide bandwidth and with high spectral resolution over a narrow bandwidth. Thus, one could simultaneously cover an extremely broad velocity range while providing high spectral resolution of groups of lines within that range. Several science examples will be presented illustrating ALMA's potential for transforming the millimeter and submillimeter study of masers.